Vitamin K2: 8 reasons why you need this bone-building & cancer-fighting nutrient


Vitamin K2: What is it?

Chickens on a low-fat diet ended up with internal bleeding. From the study of the lipid profiles of their diets, it was observed that a particular vitamin was missing. This vitamin was found to be a coagulant, and would have helped with the clotting. Since the German word for coagulant is “Koagulant”, this particular vitamin was named vitamin K. That is how vitamin K got its name.

Vitamin K is a fat-soluble vitamin. There are two species of vitamin K, vitamin K1 and vitamin K2. Vitamin K1 is also known as phylloquinone. Vitamin K2 is a group of compounds called menaquinones. Menaquinones are present in various animal-based foods such as meat and cheese. They are also present in fermented plant-based products such as fermented cabbage.

The fermentation of soybeans with bacillus natto produces Natto, a Japanese dish that has the highest content of vitamin K2. Bacteria in the human gut can also produce menaquinones (vitamin K2). The bacteria convert vitamin K1 into vitamin K2. However, the K2 produced in the intestine remains embedded within a membrane and may not be fully available to the body. Therefore, there is a need to eat vitamin K2-rich foods as well.

Initially, it was thought that vitamin K1 and vitamin K2 are two forms of the same vitamin with identical physiological functions. Recent research has proven that this is not true. In fact, though vitamin K1 plays a main role in blood clotting, the role of vitamin K2 extends far beyond blood clotting. It is also present throughout the body more than vitamin K1.

Benefits of vitamin K2

Management of Osteoporosis

Osteoporosis is a disease in which the bones mass reduces over time and they become weak. It happens when old bone mass removal is not compensated by new bone mass addition. In other words, it is when the body makes less bone mass or loses bone mass, or both. T-cells help keep the human immune system functioning well. T-cell activation actually is a major cause of osteoporosis.

It has been observed that women with post-menopausal osteoporosis have a greater number of activated T-cells circulating in their bodies. A study was conducted to determine whether vitamin K2 helps suppress T-cell proliferation. Vitamin K2 indeed suppresses T-cell proliferation, which in turn reduces the risk of osteoporosis in such cases.

It was also observed that vitamin K2 promotes the differentiation of osteoblasts, which are key to formation of bone mass. In this way also, it reduces the risk of osteoporosis.

Reduces vascular calcification

Cardiovascular disease is a leading cause of death worldwide. There were 17.92 million deaths due to cardiovascular disease in 2015. It has been forecasted to increase to as high as 23.3 million by 2030. The situation is dire.

Scientists have been investigating the usefulness of vitamin K2 in battling vascular calcification, especially in hemodialysis patients, where it is a problem. Vascular calcification is the deposition of minerals on the walls of the arteries and nerves in your body. These minerals stick to the fatty deposits that are already present on the walls of the blood vessels in your body. Matrix GLA protein has been found to be a potent inhibitor of vascular calcification. It has been found in cartilage, soft tissue, and bones. It has also been found on the walls of blood vessels, where it is secreted by vascular muscle cells.

However, Matrix GLA protein is highly dependent on vitamin K2 to achieve this purpose. This is where supplementation of vitamin K2 helps. In a study conducted, it was further reported that vitamin K2 not only reduced vascular calcification but also helped prevent the stiffening of arteries.

The calcification of veins has also been shown to be a reason for varicose veins. This means that vitamin

Reduces the risk of colon cancer

Colon (or colorectal) cancer is a complex digestive disease that affects a great number of people worldwide and is the third-largest cause of mortality from cancer. Studies have proven that vitamin K2 can reduce intestinal tumorigenesis in mice. The mice were subjected to chemically –induced tumors.

However, vitamin K2 administration led to substantial reduction in the size of the tumors. This was achieved by vitamin K2 through a modulation of the gut bacteria which are involved in the development of colon cancer.

Hyperplasia is another condition associated with cancer. In hyperplasia, the organ or tissue is enlarged during the initial stages of a cancer. The administration of vitamin K2 also helped to reduce hyperplasia and inflammation in the organs of the mice.

Reduces the recurrence of hepatocellular carcinoma

Hepatocellular carcinoma is the most common form of primary liver cancer. It is found largely in those who are affected by chronic liver disease such as hepatitis-induced cirrhosis. Surgery or a transplant can cure Hepatocellular carcinoma in its initial stages. However, in later stages, it cannot be cured though the patient’s life may be extended by better treatment and care.

Even in cases where the patient has been cured and the cancer has been removed, the risk of recurrence is still quite high. It was observed that the administration of vitamin K2 helped reduce the risk of recurrence of hepatocellular carcinoma.

In a recent study, a combination of vitamin K2 and a compound called an angiotensin-converting enzyme inhibitor (ACE-I) was used. These were administered over a period of 36-48 months. A positive result was obtained, with an inhibition of the recurrence of the cancer.

Reduces the risk of type 2 diabetes

Osteocalcin is a protein that is vitamin K2-dependent. The activation of some proteins helps increase the insulin sensitivity of the body. This is how vitamin K2 may be able to reduce the risk of type 2 diabetes.

In a recent study to investigate the effects of vitamin E on the risk of diabetes mellitus, about 300 µg of vitamin K1 and about 38 µg of vitamin K2 were administered to the patients daily. It was concluded that both vitamin K1 as well as vitamin K2 reduced the risk of type 2 diabetes.

Vitamin K2 also reduced the inflammation markers in the body in such cases. Reducing inflammation in the body also reduces the risk of type 2 diabetes. The blood lipid profile was also improved.

It was also postulated that vitamin K2 could reduce insulin resistance and the risk of type 2 diabetes. This might happen because of its effect on calcium metabolism. However, adjusting for vitamin D or calcium did not affect the associations.

Reduces the risk of kidney stones

Excess calcium and vitamin D in the body can lead to the formation of kidney stones. The problem is that vitamin D also creates a need for vitamin K2. This means that supplementation with vitamin K2 may be able to reduce the recurrence of kidney stones in patients recovering from it.

Reduces the risk of neurodegenerative diseases

Oxidative stress is caused by the presence of free radicals in the body produced as a result of metabolism. Free radicals have an unpaired electron and therefore are chemically very active as they are always seeking an excess electron. This makes them reduce the DNA, lipids, etc. in the body to obtain the electron. Antioxidants, on the other hand, can prevent this by donating an electron without becoming unstable. Antioxidants are therefore a solution to oxidative stress.

Oxidative stress has harmful effects on the human body, and is perhaps the most lethal thing within your body right now. Neurological disorders such as ischemia, Alzheimer’s disease, and Parkinson’s disease result from the oxidative damage to neurons in the body. The prevention of oxidative stress might therefore help prevent the risk of neurodegenerative diseases, as proven by several animal models.

Glutathione is an antioxidant that is produced by your body. Glutathione supplements are also available. Studies have shown that oxidative injury to neurons resulting from glutathione depletion can be remedied by the administration of both vitamin K1 and vitamin K2.

Reduces wrinkles and other signs of aging

Elastin is a protein that helps with maintaining the skin’s firmness and tightness. Elastin is responsible for the flexibility of the skin. It helps the skin return to its original shape. With age, the calcification of elastin happens, which leads to the loosening of the skin and formation of wrinkles. This is said to happen due to a build-up of vitamin D and calcium and a deficiency of vitamin K2. The deficiency of vitamin K2 prevents the activation of matrix GLA protein, which in turn leads to the calcification of elastin. Vitamin K2 can help stop the calcification of elastin and reverse the signs of aging to bring your youthfulness back! Just think about it. A few supplements of vitamin K2 might just do the trick.

What are the foods that are rich in K2?

Menaquinones are generally found in foods that are fermented by microbes. These include hard cheeses, curds, and even fermented cabbage (sauerkraut). They are also found in animal livers. They are also found in meats in generally and in fatty fish like salmon. Egg yolks are another dietary source for vitamin K2.

Side effects of Vitamin K2 intake

Both of the forms of vitamin K, vitamin K1 and vitamin K2 were found to not lead to any kind of mortality, caused by either cancer or another disease. However, other side effects were observed:

  • It can affect insulin sensitivity at higher doses.
  • If taken with anticoagulants like warfarin, it can reduce the efficacy of the drug itself owing to its coagulant nature.
  • It can interact with certain weight loss drugs.

What is the daily dose of Vitamin K2 for adults?

The daily dose of vitamin D for a healthy adult depends on the general health of the person and the medical condition. In people who were at risk of osteoporosis, it was 45 µg/day. This is the recommended daily intake for vitamin K2.

Whereas, in the case of diabetes, a 30 µg/day supplementation of vitamin K2 helped improve insulin sensitivity and reduce inflammation. Doses as high as 180 µg of Vitamin K2 have been administered to those with cardiovascular diseases. No adverse side effects were reported.

Should you be taking vitamin K2 to boost your health?

Based on the studies, the answer is a resounding yes. You definitely need this vitamin. As discussed earlier, though the gut bacteria synthesize this, it is not available completely to the body. Most of the vitamin K2 that the body needs comes from our foods. A diet that is rich in the vitamin K2 foods mentioned in this article should really help your overall health. If you feel you need to take vitamin K2 supplements, please consult a doctor. A doctor would also be able to give you a better idea of how much vitamin K2 you must take.

Want to live a healthy lifestyle?

Subscribe to free FactDr newsletters.

REVAMP YOUR

If you're enjoying our website, we promise you'll absolutely love our new posts. Be the first one to get a copy!

Get factually correct, actionable tips delivered straight to your inbox once a week.

I want the latest scoop on :

We hate spam too. We will never share your email address with anyone. If you change your mind later, you can unsubscribe with just one click

By clicking Subscribe, I agree to the FactDr Terms & Conditions & Privacy Policy and understand that I may opt out of FactDr subscriptions at any time.

 

 

 

Related Posts

Trending Topics

anal sex
Anal Sex : Tips from experts on how to be kinky yet safe Whether it irks you or stokes your fantasies, anal sex has always been an intriguing…
diverticulitis diet
Diverticulitis diet: The right way to eat if you suffer from the disease Are you suffering from diverticultis but clueless about your diet ? Read this complete plan…
Penis pump: Pump your way out of erectile dysfunction One of the options to treat erectile dysfunction is by the use of a penis…
Maltitol: Things you must know about this artificial sweetener Sugar alcohols are produced by fruits and vegetables. Maltitol is an artificially produced sugar alcohol…
passion fruit juice
Passion fruit: How one exotic fruit can help you fight infections and cancer! Passion fruit: Why does this exotic fruit have such an enticing name? And how can…
Top natural diuretics: The instant benefits you can get from nature’s water pills Since diuretic drugs are known to cause side effects, it is better to choose a…
Jicama: A fiber-rich tuber for your weight loss goals Pronouced as HEE-kah-ma, Jicama is the "new kid on the block" that has taken the…
hidden benefits walking
9 benefits of walking we bet you didn’t know! Did you know walking can be the miracle pill for eternal youth? Everyone knows walking…
TBHQ: A carcinogen lingering in your child’s favorite snacks TBHQ - Why you should shun the practice of eating instant noodles or microwave popcorn…
eating disorder anorexia
Eating Disorders: Lifestyle choice or a psychological condition? Is eating disorder just a harmless bad habit? Or does it represent grim psychological disorders?…
dance health benefits
5 unbelievable effects of dance on your overall health! You enjoy dancing, but did you know what else it does to your body? Dancing…
yoga health benefits
How to practice yoga for astounding health benefits Can a 5000-year-old system be the ultimate body healer? Did you know yoga can make…
liver detox facts
7 liver detox facts and why ignoring these could kill you! Are you taking care of this organ that handles over 500 different vital functions in…
occupational hazards types
Occupational Hazards: How to vouch for your health at your workplace Occupational hazards affect millions worldwide. Chemical spills, faulty wires, deadly pathogen, and work-stress can happen…
Latest findings on Kombucha; a teacup full of yeast and bacteria How can a tea consisting of a live culture of bacteria & fungi be healthy?…
about mediterranean diet
Why you should be adopting a Mediterranean style of diet today Ever wondered why the Mediterranean diet is so healthy? One simple solution to lowering risk…
Juice Plus: Can you really replace actual fruits with pills?  Juice Plus supplements intend to fill nutritional gaps present in our daily diet. But how…
How can Kegels help you overcome weak pelvic muscles & incontinence? Kegel exercises are pelvic floor strengthening exercises that can help you overcome incontinence issues that…
Coconut oil woman
Coconut Oil: How one oil dominates the kitchen and the medicine kit too Coconut oil has been a favorite in many Asian kitchens. But more than a cooking…
Benefits of exercise: Top reasons why you should be sweating it out more in the gym Are you leading a sedentary life and still not motivated enough to get up from…
low fodmap plan
Troubled with IBS? Here’s a complete roadmap to the low FODMAP diet Leaky & inflammatory gut troubling you? No medicine bringing you relief from the pain? Why…
Melatonin: Fascinating facts on the hormone that brings you the Zzzs Did you know, melatonin - the chemical that puts you to sleep every night is…
The science behind daith piercing: Can it really cure migraine? Since the ear has several pressure points, it is believed that daith piercing activates the…
TRX: Why is this total resistance workout the best choice for your body? TRX or total resistance exercise is a form of exercise where suspension belts are used…
social media adddiction
Your health in the age of Social Media: Why is digital detox a necessity? Did you know that more than 400 million people are dangerously addicted to social media?…
lifestyle diseases
The Big 5 lifestyle diseases: How your everyday living might be killing you You'd be shocked to know how unhealthy and potentially fatal your everyday routine could be.…
eating myths debunked
8 ‘healthy eating’ myths you believed until now Is a zero-carb diet really healthy for you? Are organic products worth their cost? Did…
paleo keto diet
Paleo vs. Keto: Which diet plan is best suited for your body goals? Is eating like a caveman the right way to go? Can you really eat fats…
Improve sex life
9 best tips from around the world for better sex life How can the pungent-smelling garlic pack in a punch to your libido? How could something…
Salt dangers
Sodium chloride: The wonders and dangers of the simple table salt Sodium chloride is a salt containing sodium and chlorine ions at a 1:1 ratio. It…
Lectin: The common link of proteins between peas and people Lectins are a type of protein that are found majorly in legumes. Most people are…
Kava: Is it the healthy substitute for alcohol you have been waiting for? Native to the beautiful South Pacific islands, Kava is a famous beverage rooted in the…
Hemp Seeds: The actual science behind this controversial crop Inspite of being credited as a superfood, hemp seeds are still shrouded with layers of…
PiYo (Pilates + Yoga): Bringing you the best of both the worlds PiYo exercise routine was formulated for people who find it tedious and grueling exercise regimens…
Dragon Fruit – Blessing from Nature’s Basket The dragon fruit is packed with nutrients and yet low on calories and is the…
Creatine: Is this the right peak athletic-performance supplement for you? Creatine is the amino acid that boosts our energy. Did you know creatine supplements can…
erectile dysfunction treatment
Erectile Dysfunction: Effective tips to help you get back on charge Erectile dysfunction is a common male sexual dysfunction. Don't stress out. Just follow these amazing…
Vitamin B12: The unknown repercussions of this nutrient deficiency Vitamin B12 is also known as cobalamine; involved in the development of red blood cells…
The real reason why you shouldn’t be eating ramen noodles Instant ramen noodles might be your go-to snack for your hunger pangs. But with each…
Lauric Acid: 8 health benefits you can derive from coconuts Appropriate use of saturated fats containing lauric acid can provide you numerous health benefits. This…
Cranberry: Top reasons why you should grow this “superfruit” in your own backyard Cranberry is a favorite among foodies and health enthusiasts alike. Read more on how it…
cancer facts
8 hard-hitting truths no one tells you about cancer Did you know that 1.5 million new cases of cancer are reported every year? Can…
carrageenan seaweed
Carrageenan: How a simple seaweed extract could better your gut health & immunity Eat more ice cream to prevent cold and flu? –With carrageenan you get one simple…
acne removal tips
Anatomy of acne: 7 instant steps to kiss those zits goodbye Blackheads, whiteheads, or pimples-call them what you may. Acne is never good news.Did you know…
improve digestion weight loss
Power up your gut: 8 proven steps on how to improve your digestion Did you know you have a colony of bacteria in your gut that help you…
Milk Thistle skin
Milk Thistle: Find possible cures for fatal diseases in these purple blooms Milk thistle is well-known for treating liver conditions. However, did you know that it comes…
Jackfruit: Slice your way into higher immunity, better digestion, & more… Native to the South East Asia, the jackfruit is a fruit brimming with thousands of…
waterchestnut
Water Chestnuts: The tastiest ways to include this healthy tuber in your diet Water chestnut is not a nut after all. It is a tuber (much like the…
Female Masturbation: Tips on how to turn up the heat during a solo mission As a female, do you find yourself constantly wondering as to what is the best…
Burpees: World’s most challenging fitness routine now made simple for you The majority of the fitness regimens mainly concentrate on a particular muscle group whereas Burpees…
Surgery or home-remedy; what is the right way to treat a burn The treatment of a burn injury depends on its severity. You can save a life…
autoimmune diseases facts
Autoimmune Diseases: Find out if your body is attacking you right now Did you know your body can harm itself? What are autoimmune diseases and why does…
Trisodium Phosphate: How a paint thinner made its way into your breakfast Ever thought how toxic chemicals find their way into our foods? How can they harm…
What is the right way to take a pregnancy test? A pregnancy test is undertaken to determine if you have conceived. A home pregnancy test…
Fibromyalgia fatigue
HCG Diet: The dangers of using this diet to lose weight HCG is a natural hormone produced by both men and women that corresponds to fertility.…
What is the average penis size and why should you care? Scientifically speaking, the average size of the penis depends on numerous factors such as genes,…
sleep deprivation
Don’t let your sleep deficit grow into memory loss or heart attack Why is sleep important for us? How could sleep deprivation harm you? We bet you…
Keto diet healthy
Keto Diet: Did you know you could eat fats to burn fats? Keto diet - A wonder diet that lets you eat fats and lose weight too!…
collagen benefits skin
Collagen: Get age-defying skin and faster hair growth with this miracle protein Collagen – Wrinkle-free skin, stronger nails, and thicker locks – now you have more reasons…
Isagenix diet
Isagenix Diet: Do you really need liquid meal replacements to lose weight? Isagenix Diet - What are liquid meal replacements and why is the world going ga-ga…
maltodextrin sugar
Maltodextrin: What are the hidden health benefits of this food additive? Maltodextrin is one of the few food additives that has been relatively deemed safe. Many…
Anhedonia: Does the chronic inability to feel joy affect you too? How often do you feel dragged down by an invisible force? Do you feel an…
Anticholinergics: The diverse range of diseases a single drug can easily treat What started as a novel treatment for Parkinson' disease has now become an all-encompassing drug.…
Erythritol: A healthy sugar substitute or yet another marketing ploy? Erythritol is a popular choice of a healthy alternative sweetening agent in foods. But how…
GERD heartburn
Heartburn: What are the exact symptoms and the best home remedies? There are easy home remedies for heartburn, which not only acts as a first aid…
11 unbelievable health benefits of thyme you didn’t know! Thyme is a herb that has been used in alternative medicine.It is a well known…
Orgasms: How to perfect the art of achieving intense bursts of pleasure (every time!) Orgasms are dependent not just on the sexual activity but on your partner as well.…
stress depressed anxiety
Are you depressed or just stressed? Know when to see a doctor Why are some people more anxious than others? Is being depressed the same as feeling…
fitness routine fun
10 fantastic ways to make your fitness routine more fun! Are you too bored to exercise? Do you avoid gym cause it's too monotonous? Looking…
alcohol toxic
7 startling facts that will make you quit alcohol today Does drinking really make you friendly and happy? How many calories does a can of…
sugar toxic health
Sugar: 7 new shocking truths revealed about the sweet poison Can drinking soda bring you closer to death? Is sugar slowly poisoning you and your…
antibiotic resistance
Antibiotic Resistance: How common diseases become deadly Can a cold kill you? How important is to get a flu shot? Why do…
nutritional yeast bread
Nutritional Yeast : How can a fungi culture be good for your body? Nutritional yeast: How a simple culture of fungi can transform your skin, digestion, immunity ,…
castor oil hair
Castor oil : A vitamin-rich oil for shiny locks and healthy bowels Castor oil bestows unlimited benefits, whether you use it for your hair or skin. But…
glutamine workout
Glutamine: Why is this the right choice for muscle-gain supplement? Glutamine can help you gain muscles and build higher immunity. Read more to find out…
iron food shellfish
Iron-Rich Foods: Eat these foods to keep fatigue and anemia away! How to ensure a muscles as strong as iron? Eat iron rich foods ! Iron…
black seed oil benefits
Black Seed Oil: What secret benefits could it bestow on your health? Black seeds or nigella seeds are tiny packets of health brimming with amazing benefits. Find…
Bromelain: 11 reasons why you should start adding pineapple to your pizza! If you didn't love pineapples already, here are some of the top health benefits that…
calorie counter
Calorie Counter: Count your calories before they flab Is calorie counting good? Are calories always bad for you? How do you if you…
gout diet purines
Gout Diet : Get relief from painful joints by eating these foods Are you a victim of this painful condition? Are medications providing only short relief? Find…
Cordyceps: How the Caterpillar fungus works as a proven cancer-shield Strange as it may sound, but cordyceps or "caterpillar fungus", a fungus variety native to…
L-arginine: Your search for the ultimate fitness booster ends here L-arginine is an amino acid necessary for the body to perform various functions.  It is…
Love tea, hate tannins? Rooibos tea is just what you need The market is brimming with a multitude of herbal teas. But what makes rooibos tea…
CLA: A breakthrough weight loss supplement with minimal side effects Tried every weight loss supplement in the market with no substantial gain? Why not try…
Oxalates: How healthy greens can sometimes be bad news for your kidneys Oxalates are compounds present in a majority of healthy foods. However, at times an overconsumption…
The Vegan Diet: The benevolent way of eating that wins hearts (and tummies) The vegan diet involves fauna-friendly outlook towards food. Could the diet that hopes to balance…
The complete fitness guide on how to perform Tabata This fitness routine is called Tabata workouts, which is named after Dr. Izumi Tabata who…
Burn those years of stubborn fat-deposits with a few minutes of HIIT! HIIT or high-intensity interval training seems to be the right type of fitness training that…

Related Posts

Want to live a healthy lifestyle?

Subscribe to free FactDr newsletters.

REVAMP YOUR

If you're enjoying our website, we promise you'll absolutely love our new posts. Be the first one to get a copy!

Get factually correct, actionable tips delivered straight to your inbox once a week.

I want the latest scoop on :

We hate spam too. We will never share your email address with anyone. If you change your mind later, you can unsubscribe with just one click

By clicking Subscribe, I agree to the FactDr Terms & Conditions & Privacy Policy and understand that I may opt out of FactDr subscriptions at any time.