Children Nutrition and Toxicity Profile

Vaccines child

Last Updated December 20th, 2021

What is Children nutrition and toxicity?

The nutrients which are the dietary requirement of healthy children aged 2 – 11 years old are the children nutrients. These are nutrients are very essential for the growth and development of children. The content of the heavy metals in the body of the children more than the essential amount causes heavy metal toxicity in children. It is very essential to keep a check on the nutrition and the toxicity level in children. If the abnormalities in the levels of nutrients and toxins are not monitored correctly, it can lead to worse health conditions.

What is the Children nutrition and Toxicity Profile?

The Children Nutrition and Toxicity Profile is a series of tests in the blood and the urine which helps in determining the healthy and proper functioning of various organs of the body in a child. The Children Nutrition and Toxicity Profile help in measuring and monitoring the levels of the nutrients and the heavy metals in the body of children and thus provides for the evaluation of any abnormalities in the functioning of many organs like  Kidney, Liver, Heart etc.
There are various tests which are grouped under the following categories:

Complete hemogram(28 tests)
– G6PD(1 test)
– Iron Deficiency(3 tests)
– Lipid tests(8 tests)
– Liver tests(11 tests)
– Renal tests(5 tests)
– Thalassemia tests(5 tests)
– Toxic Elements(9 tests)
– Vitamins tests(3 tests)

Why did the doctor recommend the Childen Nutrition and Toxicity Profile to my kid?

If your kid is experiencing various symptoms related to the abnormalities in the levels of the various nutrients or heavy metals in the body, the health practitioner might suggest the Children Nutrition and Toxicity Profile. 

In the case of stunted growth in children, or late growth and development in your child, the doctor might recommend the Children Nutrition and Toxicity Profile in order to specifically determine the cause of the same. The Children Nutrition and Toxicity Profile help in evaluating if the abnormal levels of the nutrients or the heavy metals are the cause of the formerly mentioned problems.

The  Children Nutrition and Toxicity Profile are compulsorily done when your kid is already undergoing the treatment for various diseases and disorders caused due to the abnormalities in the levels of various nutrients and the required amount of the heavy metals.
Obese and overweight children are recommended the Children Nutrition and Toxicity Profile tests. This test helps in determining the specific problem that’s causing obesity.

If your kid is experiencing diseases and disorders regarding various organs like kidney, liver, heart, lungs or various vitamin deficiency syndromes and disorders, the Children Nutrition and Toxicity Profile tests are highly recommended.

What are the tests which come under the Children Nutrition and Toxicity Profile?

There are several tests which come under the Children Nutrition and Toxicity Profiles. The categories with the tests under them are elaborated below:

Categories of the tests  Tests under the categories 
Complete hemogram LYMPHOCYTES – ABSOLUTE COUNT
MONOCYTES – ABSOLUTE COUNT
NEUTROPHILS – ABSOLUTE COUNT
BASOPHILS – ABSOLUTE COUNT
EOSINOPHILS – ABSOLUTE COUNT
TOTAL LEUCOCYTES COUNT
LYMPHOCYTE PERCENTAGE
MEAN CORPUSCULAR HEMOGLOBIN(MCH)
MEAN CORP.HEMO.CONC(MCHC)
MEAN CORPUSCULAR VOLUME(MCV)
MONOCYTES
MEAN PLATELET VOLUME(MPV)
NEUTROPHILS
NUCLEATED RED BLOOD CELLS
NUCLEATED RED BLOOD CELLS %
PLATELETCRIT(PCT)
HEMATOCRIT(PCV)
PLATELET DISTRIBUTION WIDTH(PDW)
PLATELET TO LARGE CELL RATIO(PLCR)
PLATELET COUNT
TOTAL RBC
RED CELL DISTRIBUTION WIDTH (RDW-CV)
RED CELL DISTRIBUTION WIDTH – SD(RDW-SD)
IMMATURE GRANULOCYTES(IG)
IMMATURE GRANULOCYTE PERCENTAGE(IG%)
HAEMOGLOBIN
BASOPHILS
EOSINOPHILS
G6PD GLUCOSE-6-PHOSPHATE DEHYDROGENASE
Iron Deficiency % TRANSFERRIN SATURATION
IRON
TOTAL IRON BINDING CAPACITY (TIBC)
Lipid tests LDL CHOLESTEROL – DIRECT
LDL / HDL RATIO
NON-HDL CHOLESTEROL
TRIGLYCERIDES
TC/ HDL CHOLESTEROL RATIO
VLDL CHOLESTEROL
HDL CHOLESTEROL – DIRECT
TOTAL CHOLESTEROL
Liver tests  GAMMA GLUTAMYL TRANSFERASE (GGT)
PROTEIN – TOTAL
ALBUMIN – SERUM
SERUM GLOBULIN
ASPARTATE AMINOTRANSFERASE (SGOT )
ALANINE TRANSAMINASE (SGPT)
SERUM ALB/GLOBULIN RATIO
ALKALINE PHOSPHATASE
BILIRUBIN -DIRECT
BILIRUBIN (INDIRECT)
BILIRUBIN – TOTAL
Renal tests CREATININE – SERUM
URI. ALBUMIN/CREATININE RATIO (UA/C)
URINARY MICROALBUMIN
CREATININE – URINE
BUN / Sr.CREATININE RATIO
BLOOD UREA NITROGEN (BUN)
CALCIUM
URIC ACID
Thalassemia tests HAEMOGLOBIN A2
HAEMOGLOBIN C
HAEMOGLOBIN D
HAEMOGLOBIN F
HAEMOGLOBIN S
Toxic elements tests  ARENIC 
BARIUM
COBALT
CHROMIUM
CADMIUM
CAESIUM
MERCURY
LEAD
SELENIUM
Vitamins tests VITAMIN B-12
25-OH VITAMIN D (TOTAL)
FOLATE

What are the preparations required for the Children Nutrition and Toxicity Profile tests?

– Fasting for 10 hours – 12 hours prior to the test is compulsory.

– No new medications are recommended before the test.

– Consult with the doctor about all the medications that your kid had been taking. If your kid is undergoing any treatment already, mention it to the doctor. The doctor might suggest stopping some of the medications or treatments which can affect the results of the Children Nutrition and Toxicity Profile tests.

What is the procedure of the Blood Test for the Children Nutrition and Toxicity Profile?

The blood sample is collected first before the blood test conducted. The blood is collected by the process of venipuncture. The venipuncture  procedure is carried out by the following steps:

– The tourniquet or an elastic band is wrapped around the upper arm. The veins become clearer and more prominent. This is very helpful for locating the vein from which blood will be drawn.

 – A syringe or needle is used for the collection of the blood. The needle or the syringe is injected into the vein for collecting the sample of the blood.

– The blood is drawn from the vein and collected into the tube of the syringe. The elastic band or the tourniquet is removed.

– After unwrapping the tourniquet, the area around the puncture is cleaned with an antiseptic. Applying antiseptic helps in preventing any further infection in the future.

– A cotton swab is dabbed or a bandage is put on the spot of the puncture for preventing bleeding. The collected sample of the blood is then sent for the Children Nutrition and Toxicity Profile.

– In the case of infants, the blood sample is collected by a pinprick on the heels of the baby.

What is the procedure of the urine test for the Children Nutrition and Toxicity Profile?

For the urine test, a sample of the urine of your kid has to be collected. The procedure is very simple. You will be provided with a container for the collection of the urine of your kid by the diagnostic centre or the laboratory. You will be provided with all the guidelines and the instructions for the storage of the sample of the urine. The collection of the urine is done by the following steps:

– Flush out the urine after excretion right in the morning. After emptying your bladder, the urine sample is collected for the time period of the next 24 hours.

– The urine passed by your kid over the period of the next 24 hours should be collected in the container provided. The collected urine sample is then stored in a cool place or in the refrigerator.

– The sample is later sent to the laboratory or the diagnostic centre for the Children Nutrition and Toxicity Profile tests.

What are the risks associated with the Children Nutrients and Toxicity Profile tests?

The tests which come under the Children Nutrition and Toxicity Profile are completely painless. There are no risks as well which are associated with tests. Some of the most common risks are related to the procedure of the collection of the blood by the venipuncture process. These most common risks are as follows:

– The condition of Haematoma which is characterized by the lump formation under the skin due to the clotting of blood is one of the most common risks which occurs during the venipuncture procedure.
Bruising and wounding can also occur during the procedure of the venipuncture.

– If the health practitioner has made too many punctures for finding the vein from where the blood sample will be collected for the tests, your kid might experience a little pain associated with that. This pain doesn’t persist. It wears off in a few hours or a day maximum. The feeling of lightheadedness and dizziness is very common among certain kids after the collection of the blood sample is done.

What is the price of the Children Nutrition and Toxicity Profile tests in India?

The price range of the Children Nutrition and Toxicity Profile tests starts from 300INR. The prices vary across the country. The prices of the tests are different depending on the location i.e. the city or the state the diagnostic centre or the laboratory is located.
 

  When will I get the results for the Children Nutrition and Toxicity Profile?

You will get your results for the Children Nutrition and Toxicity Profile tests within the next 24 hours – 36 hours after the tests are conducted.

How will I understand the result for the Children Nutrition and Toxicity Profile?

Complete Hemogram components Clinical References
LYMPHOCYTES – ABSOLUTE COUNT 1,000 and 4,800 lymphocytes in 1 microliter (µL) of blood in adults. The normal range is between 3,000 and 9,500 lymphocytes in 1 µL of blood, in children.
MONOCYTES – ABSOLUTE COUNT 100-700 per mm3
BASOPHILS – ABSOLUTE COUNT 0 to 3 basophils in each microliter of blood
EOSINOPHILS – ABSOLUTE COUNT 30 and 350 per microliter of blood
TOTAL LEUCOCYTES COUNT < or = 11 x 109/L
LYMPHOCYTE PERCENTAGE 20% to 40%
MEAN CORPUSCULAR HEMOGLOBIN(MCH) 27 to 31 picograms/cell
MEAN CORP.HEMO.CONC(MCHC) 33.4–35.5 grams per deciliter (g/dL)
MEAN CORPUSCULAR VOLUME(MCV)
 
80 to 100 fL(femtolitre)
MONOCYTES800 per microliter
 
MEAN PLATELET VOLUME(MPV) 9.4–12.3 fL( equivalent to spheres 2.65 to 2.9 µm in diameter)
NEUTROPHILS 1.5 to 8.0 (1,500 to 8,000/mm3)
NUCLEATED RED BLOOD CELLS 500 nRBCs/mm3
NUCLEATED RED BLOOD CELLS % below 1.5%
PLATELETCRIT(PCT) 0.22 – 0.24 %
TOTAL RBC 4.7 to 6.1 million cells per microliter (mcL), in men.
4.2 to 5.4 million mcL(in women)
4.0 to 5.5 million mcL(in children
HAEMOGLOBIN Male: 14-18 g/dL
Female: 12-16 g/dL
Pregnant female: >11 g/dL
Newborn: 14-24 g/d
Children: 9.5-14 g/dL 
BASOPHILS   <1% of your circulating white blood cells
EOSINOPHILS 0.0 to 6.0 percent of your blood(30 and 350 eosinophils/mm3)


Other tests Clinical Range
GLUCOSE-6-PHOSPHATE DEHYDROGENASE
 
10.15–14.71 U/g
% TRANSFERRIN SATURATION 5%-15%
IRON 16.3mg/day 
TOTAL IRON BINDING CAPACITY (TIBC) 50-120 mcg/dL
LDL CHOLESTEROL – DIRECT <110 mg/dL
NON-HDL CHOLESTEROL
 
<120 milligrams per deciliter (mg/dL) 
 
TRIGLYCERIDES
 
< 150 milligrams per deciliter (mg/dL)
VLDL CHOLESTEROL 2 to 30 mg/dL (0.1 to 1.7 mmol/l)
HDL CHOLESTEROL – DIRECT >45mg/dL
TOTAL CHOLESTEROL 100 – 129 mg/dL


Liver Enzyme Normal reference range
ALT 3 – 40 iu/l
AST 3 – 30 iu/l
ALP 30 – 100 umol/l
GGT 8 – 60 u/l
LDH 140-280 u/L
Bilirubin 3 – 17 umol/l
Total protein6 – 8.3 g/dL
Albumin 35 – 50 g/l
PT 10-14 s/ 1


Renal/ Kidney Clinical range 
CREATININE – SERUM 0.6 to 1.2 milligrams (mg) per deciliter (dL)
0.5 to 1.1 milligrams per deciliter in adult females
URI. ALBUMIN/CREATININE RATIO (UA/C) The ratio depends on the levels of the urine albumin and creatinine 
URINARY MICROALBUMIN Less than 30 mg is normal
CREATININE – URINE 955 to 2,936 milligrams (mg) per 24 hours for males.  601 to 1,689 mg per 24 hours for females
BUN / Sr.CREATININE RATIO The ratio depends on the levels of the Blood Urea Nitrogen and serum Creatinine 

BLOOD UREA NITROGEN (BUN)
7 to 20 mg/dL (2.5 to 7.1 mmol/L) 
CALCIUM  
8.5 to 10.5 mg/dl (4.3 to 5.3 mEq/L or 2.2 to 2.7 mmol/L)
URIC ACID 2.4-6.0 mg/dL (female)
3.4-7.0 mg/dL (male)


Metal name Blood reference rangeUrine Reference range
Aluminum less than 10 µg/L 5.6 to 15.6 μg/g
Arsenic  Less than 50 mcg/L ≤ 50 mcg/L
Barium  1.0–7.0 mg/L 1.5 µg/L(approx.)
Cadmium  0.03–0.12 μg/dl 0.185 µg/L
Caesium  1-300ng/g-NA-
Mercury  10-20μg/L 10 mcg of mercury/24-hour
Lead  0-60 Fg/dL 0-60 Fg/dL
Tin  10-20μg/L Lesser than 100 μg/L
Bismuth  4 to 30 ng/mL 60 – 600 ng/l
Beryllium  <1.0 ng/m 0.28–1 μg/L
Antimony  Lesser than 10 µg/L  0.120–0.364 micrograms/gram
Strontium  1.2 μg/L 0.3 μg/L
Thallium less than 10 μg/mL  less than 10 μg every 24 hours
Uranium 5 ng/L 0.005–0.010 µg/L

What does it mean if my kid has abnormal levels of the components which are tested in the Children Nutrition and Toxicity Profile?

The abnormal levels of the various components indicate various range of problems. In the case of abnormal levels of the components which are tested under the Children Nutrition and Toxicity Profile, you should consult the health practitioner of your kid. He can suggest you the further steps to be taken for specific determination of the problems and the causes of the same. The doctor might recommend more tests.

 

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