Urinary Tract Infections

Urinary Tract Infections test

Last Updated December 20th, 2021

Overview

Kidney disorders, renal dysfunctions, and associated urinary ailments give rise to numerous pathological complications within the human body. A common disease of this category that is more prevalent in women after a certain age is “Urinary Tract Infections”. Numerous cases of urinary tract infections are reported each year especially in the low and middle-income countries which lack proper hygiene conditions and healthy dietary habits. According to epidemiological findings by the National Kidney Foundation, nearly 20% of women having a history of urinary tract infection are likely to develop a recurrent infection in future. Urologists worldwide are concerned about the global health burden due to a steadily increasing rate of urinary tract infections cases.

 

What are urinary tract infections?

Urinary Tract InfectionsUrinary tract infections refer to the series of symptoms which are manifested due to mild to severe infections of the urinary tract (especially in females) and the reproductive system.

These are mediated mainly by bacteria, although fungal and viral pathogens might have some role as well.

In most cases, bacterial species that enter the urinary tract are immediately removed by the body.

But in people having a weak immune capacity, these bacteria continue residing and propagating within the urinary tract and cause infections of severe nature. According to survey reports by the American Urological Association, nearly 50-60% of adult women experience urinary tract infections at some point in time.

 

Causes of urinary tract infections

The main causative agent behind urinary tract infection is the Escherichia coli bacteria. But these infections are also caused by multiple physiological, environmental and other factors which are discussed below-

  • Bacterial infections in the inner lining of the urinary tract (caused by coli)
  • Microbial infections of the urethra and reproductive system (mediated by Chlamydia and Mycoplasma species)
  • Obstruction of urinary tract due to the accumulation of protein and calcium wastes, the presence of stones (in kidney), or enlarged prostate gland in men
  • Obstruction caused by Indwelling Urinary Catheter (IDC)
  • Unprotected sexual interaction with an infected partner
  • Sanitary napkins in young females and nappies in babies
  • Accumulation of excess urine in the bladder due to Neurogenic bladder retention
  • Diabetes mellitus
  • Past occurrence of urinary tract infections
  • The structural defect of the urinary tract
  • Cysts or scars in kidney
  • Sickle cell diseases
  • Excess intake of sodium or purine in regular diet
  • Living in unhygienic conditions
  • Improper wiping or cleaning after a bowel movement (causes germs to invade the urethra)
  • Excessive and improper use of birth control pills, diaphragm or spermicides
  • Hormonal changes during pregnancy and menopause (fluctuation of estrogen level)
  • Presence of bladder or kidney tumors ( observed in people above 40)
  • Glomerular diseases or Polycystic kidney diseases
  • Malignancy of any kind especially within the urinary tract
  • Excessive intake of tobacco, alcohol, caffeine, and narcotics
  • Surgeries in the past
  • Menstrual cycle
  • Heredity of urinary tract infections
  • Dehydration due to an insufficient fluid intake

 

Symptoms of urinary tract infections

Urinary Tract Infections feverHalf of the urinary tract infections become chronic due to negligence and inadequate knowledge of the symptoms in the early stages. The following symptoms should be identified and diagnosed-

  • Frequent need for urination, especially at night
  • Passing a very weak stream of urine despite an excessive urge to urinate
  • Painful burning sensation in the bladder and urethra after passing urine
  • Feeling of a fullness of bladder even after passing urine
  • Persistent pain and feeling of pressure in the lower abdomen, pelvic region, and lower back
  • Brownish or reddish discoloration of urine (due to the presence of blood)
  • The frothy appearance of urine due to the presence of bubbles (Proteinuria)
  • Obnoxious odor and cloudy appearance of urine
  • Pain in the lower abdomen which may radiate to the pelvic region and lower extremities
  • Swollen legs, hands, feet, and face
  • Fever, nausea, and vomiting
  • Muscle cramps, body pain, and general weakness
  • Dehydrated feeling

 

Types of urinary tract infections

A broad classification of urinary tract infections is done based on the location of the infection. This is discussed below-

  • Asymptomatic urinary tract infection: It is characterized by the presence of huge amounts of bacteria in urine (greater than 1,00,000 / mL of urine). Severe and specific symptoms of urinary tract infection might not be present.
  • Symptomatic urinary tract infection: The symptoms are more severe in this case. It is further subdivided into the following types –
  • Acute cystitis: It is characterized by extreme bacterial infection (bacteriuria) wherein damage to the mucosal lining of the urinary bladder occurs. Few major symptoms of cystitis are dysuria (painful urination), nocturia (frequent urination at night), hematuria (blood in urine) and suprapubic pain.
  • Pyelonephritis: It is characterized by more than 1,00,000 bacteria in a standard sample of urine. The common complications are – inflammation of renal parenchyma, calyces, and pelvis due to systemic illnesses and failures. Pain in the flanks, pyrexia, intermittent chills, nausea and vomiting take place in this condition.

A very general classification of urinary tract infections is done based on complexity and origin of the disease-

  • Lower Urinary Tract Infection: It includes cystitis, urethritis (infection of the urethra) and prostatitis (inflammation of prostate gland).
  • Upper Urinary Tract Infection: It includes pyelonephritis, intra-renal abscess, and perinephric abscess.
  • Uncomplicated Urinary Tract infections: Minor localized cystitis may be observed which lasts for a very short duration (1-5 days).
  • Complicated Urinary Tract Infections: Infections due to structural and functional anomalies of the urinary tract. Few examples are – the presence of renal calculi and intrusion of indwelling catheters.

Few associated urinary tract infections are also observed, which are elaborated below-

  • Papillary necrosis: It is common in Diabetes patients and is marked by infection of renal pyramids. The common symptoms in this condition are- hematuria, flank pains, body chills, pyrexia and acute renal failure.
  • Perinephric and renal abscess: It arises from existing bacterial pyelonephritis and is observed in immunodeficient people. It causes partial blockage of urine flow.

 

Vulnerable groups

Urinary Tract Infections testUrinary infections usually occur after a certain age and are more common in females. But there are other vulnerable groups as well which are listed below-

  • Patients of spinal cord injuries and nerve damages around the bladder (since they experience difficulty emptying their bladders completely)
  • People having kidney stones or renal tumors
  • Males having enlarged prostate gland (reduced gland secretion leads to increased bacterial growth)
  • Patients with bladder cancer, kidney dysfunctions or any other form of malignancy
  • Patients who have undergone kidney transplants
  • Type 2 Diabetes patients
  • Immunodeficient people

 

Diagnosis

Accurate diagnosis and thorough analysis of urinary tract infections are necessary to determine the underlying causes. The following diagnostic techniques are recommended-

  • Ultrasonography (to examine abnormalities in the functioning of bladder and kidney)
  • Voiding cystourethrogram (to detect abnormalities in urethra and bladder)
  • Computerized Tomography (CT) scan
  • Magnetic Resonance Imaging (MRI)
  • Radionuclide scan (to obtain information about the kidney functions)
  • Urodynamics ( testing kidney function)
  • Cystoscopy (to detect swelling, inflammation or other signs of infection)

 

Treatment and prevention

Treatment 

  • Simple UTIs are treated with a course of antibiotics that need to be administered for 3-5 days.
  • Pain relievers are given with the antibiotics to ease the burning sensation while urinating.
  • In case the UTI is at a severe level and may have affected the kidney, a heavier dosage of antibiotics will be prescribed.
  • In case of frequent UTIs, doctors may prescribe a low-dose long-term antibiotic treatment.
  • Antibiotics post sexual intercourse will be administered in case the UTI is caused due to sexual intercourse.
  • In cases of postmenopausal UTIs vaginal estrogen therapy will be recommended.

Prevention 

  • Drink plenty of water.
  • Discuss the side effects of birth control pills with your doctor before starting the course.
  • Do not use scented feminine hygiene products.
  • Wipe from front to back when using a toilet paper.
  • Consume 1 glass of cranberry juice per day and cranberry supplements.
  • Do not hold back the urge to urinate.
  • Drink water before sexual intercourse.
  • Go to the washroom after sexual intercourse.

Facts

  • 1 in 5 women will have a urinary tract infection at least once in her life. 80% of them will have recurrent UTIs.
  • Women tend to have a higher chance of getting UTIs than men. Since their urethra is shorter it is easier for the bacteria to enter the bladder.

Facts

  • Pregnant women who have UTI have a higher chance of giving birth to premature babies or babies that are underweight at birth.
  • Wearing pantyhose or tight trousers tend to increase the chances of developing UTI. This is because they may irritate skin, trap heat, and may contribute to bacterial growth.

Facts

  • If UTIs are treated early and properly, it reduces the chances of kidney diseases and infections.
  • The risk of UTIs is higher in diabetics and in men with enlarged prostate.

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Dos and Don'ts

Dos
  • Consume a lot of water, this helps in flushing out any infections or bacteria that may be present in the body.
  • Go to the washroom when you have the feeling to urinate, holding it in can increase the chances of getting an infection.
  • Consume probiotics; they help in fighting off infections.
Don'ts
  • Indulge in sexual contact, if you have been diagnosed with a UTI; it can make the symptoms worse.
  • Consume alcohol, it can irritate the bladder.
  • Consume caffeine, as it irritates the bladder worsens the infection.

 

 

 

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Strep throat pain
Anti-Streptolysin-O Test The ASO or Anti-Streptolysin-O is a blood test designed to check for the presence of streptococcus bacterial infection…
fructosamine test
Fructosamine Test A fructosamine test measures blood sugar glucose content. Fructosamine level can indicate blood sugar level in past 2-3…
vdrl test syphilis
VDRL Test The VDRL test is a blood test that is used to diagnose sexually transmitted or venereal diseases, primarily…
HSV-1_IGG
Herpes Simplex Virus I (HSV)-IgG Test Herpes simplex virus I(HSV)-IgG is an Immunoglobulin protein that acts as an antibody & stays in the blood…
woman with abdominal pain holding ovulation calendar
Ovulation – facts to know about ovulation Learn how and when ovulation occurs, demystify common misconceptions, identify symptoms, methods of detection and right period for…
Optavia diet
The features of an Optavia diet The Optavia diet endorses pre-packaged meals and snacks called "fuelings" that are tasty, low in calorie, and incorporates…
GM Diet: The fastest way to lose weight or yet another hoax diet? General Motors started this trend of extreme dieting for 7 straight days to ensure its employees were able…
Kava: Is it the healthy substitute for alcohol you have been waiting for? Native to the beautiful South Pacific islands, Kava is a famous beverage rooted in the local culture. It…
Love tea, hate tannins? Rooibos tea is just what you need The market is brimming with a multitude of herbal teas. But what makes rooibos tea (or red bush)…
How seitan proved to be a blessing in disguise for vegans worldwide Can only meat-eaters enjoy delicious juicy steaks and burgers? With seitan, the best meat substitute available today,even vegans…
How can berberine supplements help you live longer and healthier? Berberine is a turmeric look-alike herbal extract that is credited with numerous health benefits ranging from diabetes cure…
How accurate is the hair follicle drug test? Hair follicle drug test is one of the best ways to identify drug use in professional circles. But…
Bubble Tea: Bubbling with nutrition or a hidden sugar mine? The tapioca pearls present in the tea looks like bubbles and hence the name bubble tea became popular.…
Balneotherapy jacuzzi
5 things you didn’t know about balneotherapy and how you can do it at home Sauna baths have been popular since a long time. But how much more beneficial can balneotherapy be as…
CT-scan-machine
CT – Computed Tomography Scan CT scan or computed tomography scan is an diagnostic imaging technique where cross-sectional images of body are obtained…
blood elements analysis
Blood Element Analysis Test A blood element analysis is a blood test performed to measure the level of toxic elements such as…
antihepatitis core antigent
Anti-Hepatitis B Core Antigen (AHBc) Total Anti-hepatitis B core antigen (AHBC ) is a blood examination and the only serological marker of infectious blood…
antiHEV IgM test
Anti hepatitis E virus (Anti HEV) IgM Test Anti HEV IgM test determines the level of the IgM antibodies in the blood, The disease is often…
complement c4 test
Anemia Profile Anemia Profile test (Basic) is a blood screening test that measures the levels of important components of the…
Squid-ink-spaghetti
Squid Ink: A unique food coloring and flavoring agent Want to add a unique black color to your pasta, noodles and ice-creams? How can you use squid…
Squid-ink-spaghetti
Squid Ink: A unique food coloring and flavoring agent Want to add a unique black color to your pasta, noodles and ice-creams? How can you use squid…
Squid-ink-spaghetti
Squid Ink: A unique food coloring and flavoring agent Want to add a unique black color to your pasta, noodles and ice-creams? How can you use squid…
acne removal tips
Anatomy of acne: 7 instant steps to kiss those zits goodbye Blackheads, whiteheads, or pimples-call them what you may. Acne is never good news.Did you know some of the…
improve digestion weight loss
Power up your gut: 8 proven steps on how to improve your digestion Did you know you have a colony of bacteria in your gut that help you in digesting food?…
Horny Goat Weed: Can it improve libido in human beings too? This plant got its name as Horny Goat Weed when one of the goats feeding on the plant…
Rick Simpson’s Oil: The truths and controversies of this cannabis product Rick Simpson's Oil is an extract from the much-controversial plant, Cannabis. What is the actual truth behind the…
Erythritol: A healthy sugar substitute or yet another marketing ploy? Erythritol is a popular choice of a healthy alternative sweetening agent in foods. But how healthy can a…
Oxalates: How healthy greens can sometimes be bad news for your kidneys Oxalates are compounds present in a majority of healthy foods. However, at times an overconsumption of these could…
sodium blood test
Blood Sodium Test A blood sodium test measures the amount of sodium (an important electrolyte) in your body. It is also…
pilonidal sinus
Pilonidal sinus Pilonidal sinus is more common in young men than women. Learn about treatment options, surgical management, risks, and…
hidden benefits walking
9 benefits of walking we bet you didn’t know! Did you know walking can be the miracle pill for eternal youth? Everyone knows walking is good for…
aspartame or sugar
Aspartame – Hidden truths about this storm in a teacup Aspartame, the artificial sweetener, has gone under the scanner on several occasions for allegedly doing more harm than…
gallbladder diet tomato
Gallbladder surgery :Tips on post-operative care and diet What to eat post a gallbladder surgery? What are the key things to avoid if you had a…