Androstenedione Test

dhea adrenal

Last Updated December 20th, 2021

What is Androstenedione?

Androstenedione is a hormone belonging to the androgen group which is one of the most integral male sex hormones.  Even though it is a male hormone, it is also found in females especially the premenopausal women.

Androstenedione is a precursor androgen which is converted by the body into a more potent or active form like testosterone in males and estrogen in females. The production of the Androstenedione happens in the ovaries in females and in the testes for the males.

The production of the Adestenedione in the ovaries and testes is regulated by the pituitary hormone called LH(Luteinizing Hormone). The ACTH(AdrenoCorticotropic Hormone) is responsible for the regulation of the secretion of the Androstenedione by the adrenal glands.

What is the Androstenedione test?

Androstenedione test is used to measure and monitor the levels of the Androstenedione in the blood. The levels of the Androstenedione is variable diurnally as well as during the menstrual cycle of a woman.

Why did my doctor recommend me the Androstenedione test?

The Androstenedione test can be used for the diagnosis of various conditions. If your doctor has recommended you to undergo the Androstenedione test, for the following reasons as listed below.

– Since the Androstenedione hormone is produced by the adrenal gland, the test of the levels of the Androstenedione helps in the evaluation of the functioning of the adrenal gland. Your doctor might suggest you undergo the Androstenedione test for assessing the functioning of the adrenal glands.

– The Androstenedione acts as the tumor marker for the adrenal gland. Your doctor might recommend the Androstenedione test if he wants to diagnose any malignancy in the adrenal glands.

– If your doctor wants to diagnose the reasons for the early puberty, he might suggest you undergo the Androstenedione test.

– The reasons for the development of the male characteristics in females(virilization) like facial hair etc are also diagnosed using the Androstenedione test. Your doctor might recommend the Androstenedione test for the same.

– Your healthcare practitioner might need to evaluate the functioning of your testes and ovaries. Hence, you have been recommended to undergo the Androstenedione test.

– To diagnose the Congenital Adrenal Hyperplasia(CAH) or to evaluate if your body is responding to the CAH treatment, your doctor can suggest you undergo the Androstenedione test.

When should I go for the Androstenedione test?

There are various symptoms related to the abnormal levels of the Androstenedione. If you have been experiencing such symptoms, it is always suggested to undergo the Androstenedione test. Some of the common symptoms are as follows:

– Excessive body hair and facial hair growth in females(Hirsutism).
– Missing menstrual periods every month(Amenorrhea).
– Getting lesser than 6-8 menstrual cycle per year (Oligomenorrhea).
– Infertility
– Early or late puberty in both males and females.

If you are experiencing various symptoms of CAH(Congenital Adrenal Hyperplasia), it is significant to undergo the Adrenostenedione test. The common symptoms of the CAH are:

– Dehydration
– A sudden shift of appetite
-Diarrhea
-Frequent vomiting and nausea
-An irregular rhythm of the heartbeat
-Low blood pressure
– Very low blood sodium levels
– Having very low blood glucose levels.
-Acid toxicity in the blood (metabolic acidosis)
– Abrupt weight loss
– Difficulty in concentration
 

What are the preparations required for the Androstenedione test?

There are no specific preparations required for the Androstenedione test.

– Fasting is not required.
– No new medications are included.
– All the old medications can be continued. Consult with your doctor and tell him about all the medicines that you had been taking. He might suggest you stop certain hormonal medications which can affect the results.
– The specimen is collected generally in the morning.
– In the case of menstruating women, the specimen of blood is collected 1 week before or after the menstrual cycle.

What is the procedure of the Androstenedione test?

The  Androstenedione test is conducted by the blood sample collection. The blood sample is collected by the procedure of venipuncture. The process of venipuncture is done by the following ways elaborated in the steps below:

– A tourniquet or a tight elastic band is wrapped around the upper arm of an individual. This makes the veins more prominent making it easier to locate the vein to withdraw the blood sample from.

– A syringe or a needle is injected into the vein from which the blood sample is withdrawn.

– The blood sample is collected in the tube of the syringe. The tourniquet is unwrapped and an antiseptic is applied on the spot of the puncture. The spot of the puncture is dabbed with a cotton swab or a bandage is put. This helps in stopping any further bleeding.

– The collected blood sample is then sent to the laboratory for the Androstenedione test.
 

Is the Androstenedione test painful?

The Androstenedione test is conducted by the collection of the blood sample. The blood sample collection is done in the safest way called venipuncture. This procedure of the blood collection might involve a pinpricking sensation when the needle gets injected. This feeling fades away in a few hours or a day maximum.
 

What are the risks associated with the Androstenedione test?

There are no risks associated with the Androstenedione test. The procedure of the blood collection involves some minute risks.

– One can experience pain due to so many punctures. This pain wears off in some time.

– Some people might feel lightheaded and dizzy after the collection of the blood sample.

– There’s a chance of Haematoma(clotting of blood under the skin forming lumps).

– Bruising and bleeding are the most common risks associated with the Venipuncture procedure.
 

What is the price of the Androstenedione test?

The price range of the Androstenedione test in India starts from Rs 1800 It might vary depending on the location of the diagnostic center i.e. the city or the state the diagnostic center is located in.
 

When will I get my results for the Androstenedione test?

You will get your results for the Androstenedione within 24 hours to 36 hours of the test.

How to understand my results for the Androstenedione test?

Age (male) Clinical reference(in nmol/L)
18 – 30 years 175-768
31 – 50 years 140-663 
51 – 60 years 175-768


Menstrual Stages (females) Clinical reference(in nmol/L)
Follicular  122-873
Mid-cycle  209-995
Luteal  105-820
Postmenopausal 70-262


Age (children) Clinical reference(in nmol/L)
1-12 months 21-272
1-4 years 17-178
5-9 years 21-401 
10-13 years  42-771
14-17 years  77-785

What does it mean if I have higher levels of the Androstenedione?

If you  are a female and you have a higher level of Androstenedione in your blood, it indicates the following conditions:

– Excess growth of body hair (hirsutism)
– An abnormal pattern of menstrual periods or irregular menstrual periods.
– Early puberty
– PCOS(PolyCystic Ovarian Syndrome)
– Virilization(development of  male characteristics)
– Amenorrhea(missing out monthly periods or getting lesser than 4-6 menstrual periods throughout the year) 
– Adrenal tumors 
– CAH(Congenital Adrenal hyperplasia)

If you are a male, the signs and symptoms of the increased level of the Androstenedione are not noticeable. The most common things indicated by the higher levels of the Androstenedione in males are:
– Adrenal tumors 
– Adrenal glands failing to work properly
– CAH(Congenital Adrenal Hyperplasia)

What does it mean if I have lower levels of the Androstenedione?

If you are a female with the levels of Androstenedione lower than the clinical range according to your age and phase, it can indicate the following conditions:

– The incapability of the adrenal glands to work the way that it should.
– Previous surgical removal of the ovaries in a female.
– Hypopituitarism(the condition in which the pituitary gland does not produce the hormones required in the correct amount).
– Early menopause
 
If you are a male with the levels of the Androstenedione lower than that of the clinical range according to the age, it indicates the following conditions:

– Addison’s disease or primary adrenal insufficiency in which the adrenal glands stop functioning the way it is required to work.
– In the case of late puberty, the levels of the Androstenedione is very low.
– CAH(Congenital Adrenal Hyperplasia)
– Dysfunction of the pituitary gland because of the tumors.
– Kallman syndrome (this condition signifies the abnormal development of the hypothalamus which is a hormone controlling gland in the brain).
– The incapability of testes to produce enough Androstenedione.
 

Is the Androstenedione test recommended during pregnancy?

Androgens play a very pivotal role during the gestational period. The abnormal levels of the Androgens have adverse health effects on the fetus. Hence, it is very important for pregnant women to undergo the tests for androgens. You need to undergo the test for the Androstenedione which is a type of androgen hormone along with the other androgen tests if your doctor recommends it according to your other health conditions.   

Is the Androstenedione test recommended for my newborn?

There are various effects of the abnormal levels of the Androstenedione on the kid. It is highly recommended for your newborn to undergo the Androstenedione test if a condition of ambiguous external genitalia is noticed. Under this condition, the higher levels of the androstenedione and other androgens lead to the newborn to have sex organs which not clearly male or female.

When should I take my kid for the Androstenedione test?

If your kid is experiencing early or late puberty, it’s highly recommended for your kid to undergo the Androstenedione test. 
In the case of experiencing the symptoms of CAH(Congenital Adrenal Hyperplasia), your kid is suggested to take the Androstenedione test. Some of the common symptoms of the CAH(Congenital Adrenal Hyperplasia) are listed below-

In the case of a female child, the common symptoms of CAH might be as follows:

– A deep and husky voice like males
– Excess growth of hair on the face and body
– Missing out monthly menstrual periods or irregular periods
– Changes related to early puberty such as hair in the armpits and pubic area
– Severe acne and pimples problem.
– Male-pattern baldness (loss of hair near the temples)
 
In the case of a male child, the symptoms of the CAH might be as follows:

– Development of muscles at an early age
– Early puberty with the early growth of armpit hair and pubic hair.
– Enlargement of the penis during childhood
– Deepening of the voice earlier than the age of normal puberty
– Early growth of beard
– Smaller testicles than normal
– Severe acne and pimples

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11 unbelievable health benefits of thyme you didn’t know! Thyme is a herb that has been used in alternative medicine.It is a well known…
Exercises or diet? Find out the healthiest way to gain weight Tired of being called skinny all the time? Looking for healthy ways to beef up?…
Isagenix diet weight loss
How are BMI and BMR different and what do these numbers mean? BMI and BMR are two important metrics that provide a clear picture of your body's…
hsv igg test
Herpes Simplex Virus I (HSV)-IgG Test Herpes Simplex Virus I (HSV)-IgG is used to detect the presence of the herpes virus…
reflexology massage
Top reasons why you should go for a reflexology massage today Reflexology involves the application of pressure to your feet and hands to encourage self-healing. Could…
cytomegalovirus igm test
Cytomegalo Virus (CMV) – IgM Test The CMV antibodies include both IgM and IgG antibodies which are the immune system's response…
Eustachian Tube : Functions and top home remedies to prevent its infection Pressure equalization, mucus drainage and protecting the middle ear from bacteria and viruses are the…
Love tea, hate tannins? Rooibos tea is just what you need The market is brimming with a multitude of herbal teas. But what makes rooibos tea…
cardiolipin antibody igm
Cardiolipin Antibody (ACL) –IgM Test This particular test measures the level of IgM type antibodies in the blood by using…
Bubble Tea: Bubbling with nutrition or a hidden sugar mine? The tapioca pearls present in the tea looks like bubbles and hence the name bubble…
healthy habits
10 healthy habits: Have a hearty kick-start to the New Year! Do you set goals that are too difficult for you to maintain? Are to struggling…
maltodextrin sugar
Maltodextrin: What are the hidden health benefits of this food additive? Maltodextrin is one of the few food additives that has been relatively deemed safe. Many…
Vagus nerve: 7 health benefits of stimulating the “gut-brain” connection As a matter of fact, there are two vagus nerves namely the left and the…
lipase test
Lipase Test A lipase test is a blood test performed to quantitatively measure the level of the…
complement c4 test
Anemia Profile Anemia Profile test (Basic) is a blood screening test that measures the levels of important…
diagnosis of lipoma
Lipoma Click to know all about lipoma, its causes, types, risks, diagnosis , and treatment of…
diagnosis of lipoma
Lipoma Click to know all about lipoma, its causes, types, risks, diagnosis , and treatment of…
beta alanine energy powder
Beta-alanine: A powerhouse of proteins to charge up your workout How can a simple amino acid be a crucial health supplement for champion athletes? Find…
GGt test
GGT – Gamma-Glutamyl Transferase Test GGT or gammaglutamyl transferase test is a liver function test that is used to detect…
The Cabbage Soup Diet: The healthiest way to instant weight loss Cabbage soup diet rapid weight loss diet for those who want to shed those extra…
green poop causes
Green poop : What are the reasons and how can you correct it Ever sneak a peek down the toilet only to shockingly find green poop? Why does…
apolipoprotein a1 test
Apolipoprotein -A1 (APO-A1) Test Apolipoprotein A-I (Apo-A1) constitutes 70% of protein content in high-density lipoprotein (HDL) and helps in…
hYdroxycut pills
Hydroxycut: How safe are these so-called weight loss supplements? Hydroxycut is a blend of several different ingredients formulated to promote weight loss; powered by…
geriatric health aging
Geriatric health: Do you still think age is just a number? Aging is an inevitable part of life. But don't let these common geriatric ailments affect…
Beware of these common foods that cause high bodily inflammation! Maybe its the long list of inflammatory foods in your diet that is making you…
thyroid_scan
Thyroid Scan Thyroid scan is a diagnostic procedure that aims to view the thyroid gland and detect…
adenosine deaminase
Adenosine Deaminase Test Adenosine Deaminase is a protein that is produced by most cells of the body that…
Pelvic_ultrasound
Pelvic Ultrasound Pelvic ultrasound is a process where sound waves are used to create image of your…
boost immunity tips
Step up your defence: 15 proven tips on how to boost your immunity Want to naturally build up a stronger immunity? Tired of frequent colds and runny nose?You…
Vitamin K2: 8 reasons why you need this bone-building & cancer-fighting nutrient Vitamin K2 is claimed to be essential for your bone health, for reducing the risk…
Grass-fed meat
Facts about grass-fed meat Grass-fed meat has a rich source of vitamins, minerals, and are low in fat and…
c peptide test
C-Peptide test C-peptide is a blood or urine test which is used to monitor and assess the…
waking up tired
10 reasons why you might be waking up tired Do you feel you are not getting enough sleep? Sleep-deprived and frustrated? Read on discover…
Infertility man
Infertility profile (men) The group of tests that for a part of the infertility profile testing for men…
How can Kegels help you overcome weak pelvic muscles & incontinence? Kegel exercises are pelvic floor strengthening exercises that can help you overcome incontinence issues that…
malarial antigen test
Malaria Antigen Test A malaria antigen test is a rapid diagnostic test (RDT) that can detect malarial antigens…
Proteinuria and blood pressure
Hypertension Profile Hypertension profile is a panel of blood tests done to analyse the cause of hypertension…
Dunning kruger effect
Medical Mythbusters : How many of these myths did you think were true? Do vaccines cause autism? Does sugar really make kids hyperactive? Don't fall prey to these…
Women with biltong slices
A few details about Biltong How can you prepare the perfect Biltong? How's it different from jerky?What are its uses,…
liver biopsy procedure
Liver Biopsy Liver biopsy or hepatic biopsy is a diagnostic tool that collects a sample of live…
Moringa drink
Moringa: This could be the most nutrient-dense food known to us! Moringa is a lush green tree brimming with over 90 essential nutrients required for a…
Tart Cherry: The healthiest excuse for taking that second serving of pie Tart cherry has been traditionally used in delectable desserts such as pies. Recent studies have…
top 5 deadliest cancers
A sneak peek into the top 5 deadliest cancers and the true nature of their origins Did you know that cancer is the 2nd leading cause of deaths globally? Among the…
turmeric skin
We bet you didn’t know that turmeric could be this beneficial! Did you know that turmeric, a humble ingredient found in most Indian kitchens could cure…
L-theanine attention
L-Theanine: Better sleep, higher focus, and many other benefits Did you know that L-theanine found in green tea can make you sleep better and…
PiYo (Pilates + Yoga): Bringing you the best of both the worlds PiYo exercise routine was formulated for people who find it tedious and grueling exercise regimens…
Bromelain: 11 reasons why you should start adding pineapple to your pizza! If you didn't love pineapples already, here are some of the top health benefits that…
Nootropics: How safe are these drugs that make you smarter? Nootropics is a group of cognition-enhancing substances that facilitate better learning, memory, and other executive…
The tell-tale signs of pregnancy you should know A missed period is considered the first sign of pregnancy. Learn what are the other…
complement c3 test
Complement 3 (C3) Test The complement 3 test measures the level of C3 protein in the blood, a vital…
Nitric oxide: Why is this heart-healthy supplement every sportsman’s first choice? Once considered a vastly toxic substance, nitric oxide is now deemed to be a great…
Neurologist: How can the specialist help you avert fatal diseases A medical doctor who specializes in the field of neurology is called the neurologist. Find…
Omega 3: Now you know why fats are healthy for you What do egg yolks, fatty fish, and avocados have in common? In addition to being…
Sore Throat: How to treat this throat infection at home? Do frequent cold and cough hamper your daily life? Are these followed by a pain…
Cranberry: Top reasons why you should grow this “superfruit” in your own backyard Cranberry is a favorite among foodies and health enthusiasts alike. Read more on how it…
autoimmune diseases facts
Autoimmune Diseases: Find out if your body is attacking you right now Did you know your body can harm itself? What are autoimmune diseases and why does…
anti-thyroglobulin antibody
Anti-Thyroglobulin Antibody test Anti-thyrogloubin antibody test measures the level of antibodies that attack the thyroid gland cells and…
Poop chart: Top things you didn’t you your poop could reveal about you Bristol poop chart was designed during the 1990s in order to help doctors identify various…

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