Androstenedione Test

dhea adrenal

Last Updated December 20th, 2021

What is Androstenedione?

Androstenedione is a hormone belonging to the androgen group which is one of the most integral male sex hormones.  Even though it is a male hormone, it is also found in females especially the premenopausal women.

Androstenedione is a precursor androgen which is converted by the body into a more potent or active form like testosterone in males and estrogen in females. The production of the Androstenedione happens in the ovaries in females and in the testes for the males.

The production of the Adestenedione in the ovaries and testes is regulated by the pituitary hormone called LH(Luteinizing Hormone). The ACTH(AdrenoCorticotropic Hormone) is responsible for the regulation of the secretion of the Androstenedione by the adrenal glands.

What is the Androstenedione test?

Androstenedione test is used to measure and monitor the levels of the Androstenedione in the blood. The levels of the Androstenedione is variable diurnally as well as during the menstrual cycle of a woman.

Why did my doctor recommend me the Androstenedione test?

The Androstenedione test can be used for the diagnosis of various conditions. If your doctor has recommended you to undergo the Androstenedione test, for the following reasons as listed below.

– Since the Androstenedione hormone is produced by the adrenal gland, the test of the levels of the Androstenedione helps in the evaluation of the functioning of the adrenal gland. Your doctor might suggest you undergo the Androstenedione test for assessing the functioning of the adrenal glands.

– The Androstenedione acts as the tumor marker for the adrenal gland. Your doctor might recommend the Androstenedione test if he wants to diagnose any malignancy in the adrenal glands.

– If your doctor wants to diagnose the reasons for the early puberty, he might suggest you undergo the Androstenedione test.

– The reasons for the development of the male characteristics in females(virilization) like facial hair etc are also diagnosed using the Androstenedione test. Your doctor might recommend the Androstenedione test for the same.

– Your healthcare practitioner might need to evaluate the functioning of your testes and ovaries. Hence, you have been recommended to undergo the Androstenedione test.

– To diagnose the Congenital Adrenal Hyperplasia(CAH) or to evaluate if your body is responding to the CAH treatment, your doctor can suggest you undergo the Androstenedione test.

When should I go for the Androstenedione test?

There are various symptoms related to the abnormal levels of the Androstenedione. If you have been experiencing such symptoms, it is always suggested to undergo the Androstenedione test. Some of the common symptoms are as follows:

– Excessive body hair and facial hair growth in females(Hirsutism).
– Missing menstrual periods every month(Amenorrhea).
– Getting lesser than 6-8 menstrual cycle per year (Oligomenorrhea).
– Infertility
– Early or late puberty in both males and females.

If you are experiencing various symptoms of CAH(Congenital Adrenal Hyperplasia), it is significant to undergo the Adrenostenedione test. The common symptoms of the CAH are:

– Dehydration
– A sudden shift of appetite
-Diarrhea
-Frequent vomiting and nausea
-An irregular rhythm of the heartbeat
-Low blood pressure
– Very low blood sodium levels
– Having very low blood glucose levels.
-Acid toxicity in the blood (metabolic acidosis)
– Abrupt weight loss
– Difficulty in concentration
 

What are the preparations required for the Androstenedione test?

There are no specific preparations required for the Androstenedione test.

– Fasting is not required.
– No new medications are included.
– All the old medications can be continued. Consult with your doctor and tell him about all the medicines that you had been taking. He might suggest you stop certain hormonal medications which can affect the results.
– The specimen is collected generally in the morning.
– In the case of menstruating women, the specimen of blood is collected 1 week before or after the menstrual cycle.

What is the procedure of the Androstenedione test?

The  Androstenedione test is conducted by the blood sample collection. The blood sample is collected by the procedure of venipuncture. The process of venipuncture is done by the following ways elaborated in the steps below:

– A tourniquet or a tight elastic band is wrapped around the upper arm of an individual. This makes the veins more prominent making it easier to locate the vein to withdraw the blood sample from.

– A syringe or a needle is injected into the vein from which the blood sample is withdrawn.

– The blood sample is collected in the tube of the syringe. The tourniquet is unwrapped and an antiseptic is applied on the spot of the puncture. The spot of the puncture is dabbed with a cotton swab or a bandage is put. This helps in stopping any further bleeding.

– The collected blood sample is then sent to the laboratory for the Androstenedione test.
 

Is the Androstenedione test painful?

The Androstenedione test is conducted by the collection of the blood sample. The blood sample collection is done in the safest way called venipuncture. This procedure of the blood collection might involve a pinpricking sensation when the needle gets injected. This feeling fades away in a few hours or a day maximum.
 

What are the risks associated with the Androstenedione test?

There are no risks associated with the Androstenedione test. The procedure of the blood collection involves some minute risks.

– One can experience pain due to so many punctures. This pain wears off in some time.

– Some people might feel lightheaded and dizzy after the collection of the blood sample.

– There’s a chance of Haematoma(clotting of blood under the skin forming lumps).

– Bruising and bleeding are the most common risks associated with the Venipuncture procedure.
 

What is the price of the Androstenedione test?

The price range of the Androstenedione test in India starts from Rs 1800 It might vary depending on the location of the diagnostic center i.e. the city or the state the diagnostic center is located in.
 

When will I get my results for the Androstenedione test?

You will get your results for the Androstenedione within 24 hours to 36 hours of the test.

How to understand my results for the Androstenedione test?

Age (male) Clinical reference(in nmol/L)
18 – 30 years 175-768
31 – 50 years 140-663 
51 – 60 years 175-768


Menstrual Stages (females) Clinical reference(in nmol/L)
Follicular  122-873
Mid-cycle  209-995
Luteal  105-820
Postmenopausal 70-262


Age (children) Clinical reference(in nmol/L)
1-12 months 21-272
1-4 years 17-178
5-9 years 21-401 
10-13 years  42-771
14-17 years  77-785

What does it mean if I have higher levels of the Androstenedione?

If you  are a female and you have a higher level of Androstenedione in your blood, it indicates the following conditions:

– Excess growth of body hair (hirsutism)
– An abnormal pattern of menstrual periods or irregular menstrual periods.
– Early puberty
– PCOS(PolyCystic Ovarian Syndrome)
– Virilization(development of  male characteristics)
– Amenorrhea(missing out monthly periods or getting lesser than 4-6 menstrual periods throughout the year) 
– Adrenal tumors 
– CAH(Congenital Adrenal hyperplasia)

If you are a male, the signs and symptoms of the increased level of the Androstenedione are not noticeable. The most common things indicated by the higher levels of the Androstenedione in males are:
– Adrenal tumors 
– Adrenal glands failing to work properly
– CAH(Congenital Adrenal Hyperplasia)

What does it mean if I have lower levels of the Androstenedione?

If you are a female with the levels of Androstenedione lower than the clinical range according to your age and phase, it can indicate the following conditions:

– The incapability of the adrenal glands to work the way that it should.
– Previous surgical removal of the ovaries in a female.
– Hypopituitarism(the condition in which the pituitary gland does not produce the hormones required in the correct amount).
– Early menopause
 
If you are a male with the levels of the Androstenedione lower than that of the clinical range according to the age, it indicates the following conditions:

– Addison’s disease or primary adrenal insufficiency in which the adrenal glands stop functioning the way it is required to work.
– In the case of late puberty, the levels of the Androstenedione is very low.
– CAH(Congenital Adrenal Hyperplasia)
– Dysfunction of the pituitary gland because of the tumors.
– Kallman syndrome (this condition signifies the abnormal development of the hypothalamus which is a hormone controlling gland in the brain).
– The incapability of testes to produce enough Androstenedione.
 

Is the Androstenedione test recommended during pregnancy?

Androgens play a very pivotal role during the gestational period. The abnormal levels of the Androgens have adverse health effects on the fetus. Hence, it is very important for pregnant women to undergo the tests for androgens. You need to undergo the test for the Androstenedione which is a type of androgen hormone along with the other androgen tests if your doctor recommends it according to your other health conditions.   

Is the Androstenedione test recommended for my newborn?

There are various effects of the abnormal levels of the Androstenedione on the kid. It is highly recommended for your newborn to undergo the Androstenedione test if a condition of ambiguous external genitalia is noticed. Under this condition, the higher levels of the androstenedione and other androgens lead to the newborn to have sex organs which not clearly male or female.

When should I take my kid for the Androstenedione test?

If your kid is experiencing early or late puberty, it’s highly recommended for your kid to undergo the Androstenedione test. 
In the case of experiencing the symptoms of CAH(Congenital Adrenal Hyperplasia), your kid is suggested to take the Androstenedione test. Some of the common symptoms of the CAH(Congenital Adrenal Hyperplasia) are listed below-

In the case of a female child, the common symptoms of CAH might be as follows:

– A deep and husky voice like males
– Excess growth of hair on the face and body
– Missing out monthly menstrual periods or irregular periods
– Changes related to early puberty such as hair in the armpits and pubic area
– Severe acne and pimples problem.
– Male-pattern baldness (loss of hair near the temples)
 
In the case of a male child, the symptoms of the CAH might be as follows:

– Development of muscles at an early age
– Early puberty with the early growth of armpit hair and pubic hair.
– Enlargement of the penis during childhood
– Deepening of the voice earlier than the age of normal puberty
– Early growth of beard
– Smaller testicles than normal
– Severe acne and pimples

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Water Chestnuts: The tastiest ways to include this healthy tuber in your diet Water chestnut is not a nut after all. It is a tuber (much like the…
dance health benefits
5 unbelievable effects of dance on your overall health! You enjoy dancing, but did you know what else it does to your body? Dancing…
Eustachian Tube : Functions and top home remedies to prevent its infection Pressure equalization, mucus drainage and protecting the middle ear from bacteria and viruses are the…
Love tea, hate tannins? Rooibos tea is just what you need The market is brimming with a multitude of herbal teas. But what makes rooibos tea…
The right way to prepare Alfalfa sprouts at home Alfalfa or lusan ghas is not just a nutritious animal fodder. This flavonoid-rich herb has…
woman with abdominal pain holding ovulation calendar
Ovulation – facts to know about ovulation Learn how and when ovulation occurs, demystify common misconceptions, identify symptoms, methods of detection and…
low fodmap plan
Troubled with IBS? Here’s a complete roadmap to the low FODMAP diet Leaky & inflammatory gut troubling you? No medicine bringing you relief from the pain? Why…
Urologist: When should you visit one and why? A urologist can treat not only genitourinary problems of both men and women but also…
Pumpkin Seeds: Why pumpkins are more than just for pies! Pumpkins have been long associated with Halloween carvings and delicious pies. But did you know…
IGE test
IgE test – Immunoglobulin E IgE or immunoglobulin E test is a test that measures the level of IgE in…
Okra: How can this nutrient-dense vegetable help you fight diabetes? Okra is a food which is rich in nutrients and minerals which are extremely essential…
Barium-enema
Barium Enema Barium enema is also known as colon x-ray. Here, the patient is asked to consume…
improve digestion weight loss
Power up your gut: 8 proven steps on how to improve your digestion Did you know you have a colony of bacteria in your gut that help you…
PROGESTERONE_test
Progesterone test The progesterone test is a blood test used to determine the level of hormone progesterone…
complement c4 test
Anemia Profile Anemia Profile test (Basic) is a blood screening test that measures the levels of important…
Rhubarb: The secret nutrients hidden in these deep red stems Rhubarb is a deep red colored stem that is often cooked with sugar to make…
APL IgM Test
Antiphospholipid Antibody(APL)-IgM test The antiphospholipid antibodies are specific protein in the body directed against the phospholipids. It is…
What is the right way to take a pregnancy test? A pregnancy test is undertaken to determine if you have conceived. A home pregnancy test…
fitness routine fun
10 fantastic ways to make your fitness routine more fun! Are you too bored to exercise? Do you avoid gym cause it's too monotonous? Looking…
dandelion health benefits
Dandelion: Little parachutes of health and wellness for your whole body Dandelions are not just bright looking blossoms that cheer your mind. These are powerpacked with…
hYdroxycut pills
Hydroxycut: How safe are these so-called weight loss supplements? Hydroxycut is a blend of several different ingredients formulated to promote weight loss; powered by…
canola oil cooking
Canola oil: How safe is it to consume this popular cooking oil? Extracted from rapeseeds, Canola oil derives its name from Canadian Oil. Did you know that…
Did you know drinking alkaline water could be the healthier choice for you? Ever wondered how safe is your drinking water in terms of pH? Recent studies have…
angiography
Angiography Angiography is a diagnostic tool used to determine the narrowing or blockage in the arteries…
Krill Oil: Does the solution to human illnesses really lie at the depths of the ocean? The word "krill" means “small fry of fish” in Norwegian. They are usually the primary…
Sushi: health benefits and recipes Sushi is a traditional Japanese dish prepared with vinegared rice served with fish (often raw),…
estrogen-patch-HRT
Hormone Replacement Therapy-Symptoms, Benefits, Types, Side Effects, Lifestyle Changes Read how you can relieve symptoms of perimenopause and menopause through hormonal replacement therapy. Weigh…
Rhodiola Rosea: Hoist yourself to high stamina and a stress-free brain Rhodiola rosea, also known as golden root, is a wonder herbal extract that can rev…
Screening_BETATHALASSEMIA
Beta-Thalassemia Screening Beta-thalassemia screening procedures involve both prenatal and post natal diagnostic methods to determine if a…
Doppler Ultrasound Doppler ultrasound can detect the nature of blood flow and can spot places where blood…
Top natural diuretics: The instant benefits you can get from nature’s water pills Since diuretic drugs are known to cause side effects, it is better to choose a…
calorie counter weight loss
Guaranteed ways to lose weight fast and shed those extra pounds! Read more to find a guaranteed step-by-step method to lose weight permanently. Losing weight was…
babyled weaning
What is Baby Led Weaning and how does it compare to traditional weaning? Baby led weaning is where the infant is allowed to gradually get into the habit…
Easy steps on how to do the plank for the perfect abs The plank exercise helps in several ways like strengthening your abs, shoulders, back and glutes.…
TRX: Why is this total resistance workout the best choice for your body? TRX or total resistance exercise is a form of exercise where suspension belts are used…
Thyroid disorders
T3 Test T3 is an important thyroid hormone. It's level is detected with the help of the…
knee prosthesis
Revision Total Knee Replacement surgery A revision total knee replacement surgery is a procedure to remove original prosthesis and replace…
BULIMIA NERVOSA vomiting
Can you get addicted to food? Learn everything about food addiction What is food addiction? How can people get addicted to eating? Is it an unhealthy…
Sharpen your brain with these top brain-friendly foods! Did you know your diet could decide how razor sharp your memory is? Or that…
50 common health conditions
What are the top 50 deadly and widespread diseases? A complete list of the top 50 most common and deadly diseases that plague humanity.…
diabetic foot ulcer remedy
Diabetic foot ulcer Read to know everything about diabetic foot ulcer,causes,symptoms,diagnosis,treatment prevention and outcome for patients
Beets: Top reasons why these nutrient-dense roots should be a staple Beets:These crunchy pink roots are brimming with healthy goodness. Blend these for an instant-energy smoothie…
Milk Thistle skin
Milk Thistle: Find possible cures for fatal diseases in these purple blooms Milk thistle is well-known for treating liver conditions. However, did you know that it comes…
HELICOBACTER_PYLORI---IgG
Helicobacter Pylori – IgG Test Helicobacter pylori IgG test is a blood, saliva, and urine test performed to determine if…
Amniocentesis test
Amniocentesis Amniocentesis is a diagnostic procedure for pregnant women to assess and detect the presence of…
social media adddiction
Your health in the age of Social Media: Why is digital detox a necessity? Did you know that more than 400 million people are dangerously addicted to social media?…
Medical conditions yoga can help with Yoga practitioners have outlined several health benefits of yoga and a daily yoga regimen can…
Medical conditions yoga can help with Yoga practitioners have outlined several health benefits of yoga and a daily yoga regimen can…
rosacea-treatment--before-_-after
The best and safest ways to treat rosacea Rosacea is a skin disease that is characterized by reddish hives and rashes on the…
How can berberine supplements help you live longer and healthier? Berberine is a turmeric look-alike herbal extract that is credited with numerous health benefits ranging…
ANTI-MICROSOMAL-ANTIBODY-(AMA)
Anti-Microsomal Antibody AMA Test AMA or anti-microsomal antibody test is a blood test that measures the activity of AMA…
Pulmonary Function Tests Pulmonary function tests (PFT’s) are non-invasive breathing tests employed for diagnosing and monitoring lung diseases…
chloride test
Chloride Test A chloride test of the blood checks the level of chloride in body, an important…
myelogram
Myelography Myelography is an important diagnostic tool that is used to investigate and identify abnormalities in…
cytomegalovirus igm test
Cytomegalo Virus (CMV) – IgM Test The CMV antibodies include both IgM and IgG antibodies which are the immune system's response…
Coconut sugar: What is it and is it healthier than table sugar? In the long list of things that the wonderful coconut gives us, coconut sugar is…
dandelion weight loss
Caralluma Fimbriata: How to eat this cactus to lose weight Caralluma fimbriata is a miracle cactus that can be safely consumed by most for losing…
Experts reveal the safest ways to perform an enema at home The idea of pushing some up your rectal area might make you queasy but an…
iron food shellfish
Iron-Rich Foods: Eat these foods to keep fatigue and anemia away! How to ensure a muscles as strong as iron? Eat iron rich foods ! Iron…
cystoscopy
Cystoscopy Cystoscopy is a procedure to check the health of the urethra and the bladder. The…
Silicon Dioxide: How can a component of sand be essential to your wellbeing? Silicon is one of the most abundant elements in the nature. Find out how silicon…
knee-replacement-3
Minimally Invasive Total Knee Replacement Unlike traditional knee replacement, a minimally invasive total knee replacement uses a shorter incision to…

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