Acute Cholecystitis

acute cholecystitis liver

Last Updated December 20th, 2021

Overview

The liver produces a greenish-yellow alkaline fluid called bile that serves as a digestive juice. The organ secretes nearly one liter of the substance every day. Bile is also known as gall. It aids in the digestion and absorption of fats and also plays a part in the elimination of certain wastes from the body. Excess bile produced by the liver is stored between mealtimes in a small pouch-like organ called the gallbladder. Bile flows into and out of the gallbladder by means of the cystic duct which feeds into the common bile duct that also carries bile directly from the liver. When food enters the small intestine during digestion, the gallbladder receives a series of impulses that cause it to contract and release bile so that it can enter the small intestine where it will participate in the digestive process.

 

What Is Acute Cholecystitis?

Acute cholecystitis painInflammation of the gallbladder is known in medical terms as cholecystitis. Often this condition is linked with gallbladder stones, although there can be other causes as well. The gallbladder stones can end up obstructing the cystic duct, blocking the flow of bile through the duct. As a result, the gallbladder becomes swollen. This condition can be quite painful and such pain is known as biliary colic. This pain may be one of the earliest signs of cholecystitis or inflammation in the gallbladder.

In acute cases, this pain sets in suddenly and without warning. It can be quite severe. A patient suffering from acute cholecystitis risks developing infections that can make matters worse. Acute cholecystitis generally develops as a complication of gallbladder stones. Having gallbladder stones is, in fact, the most common disorder of the gallbladder.

 

What Are The Causes Of Cholecystitis?

There are a number of risk factors associated with cholecystitis. Having one or more of the following risk factors does not indicate that the person will definitely develop cholecystitis. Instead, it indicates that, in comparison with someone who does not have these risk factors, the person who has them is more likely to develop inflammation in the gallbladder.

  • Having a close family member who is suffering from cholecystitis.
  • Being female is considered a risk factor as well since, on average women are significantly more likely to develop gallbladder stones than men.
  • Having a family history of gallbladder stones is associated with a higher risk.
  • Being pregnant.
  • The risk increases with age.
  • Sickle cell disease.
  • Metabolic syndrome.
  • Crohn’s disease.
  • Liver cirrhosis.
  • Prolonged fasting.
  • Long-term intravenous feeding.
  • Being obese or overweight.
  • Chronic illness.
  • Certain medications.
  • Taking oral contraceptives.
  • The condition is more common in certain ethnic groups than others.
  • Diabetes mellitus.
  • Tumors.
  • Having gallbladder stones.
  • Scarring of the bile duct.
  • Severe trauma.
  • Receiving chemotherapy.
  • Hormone replacement therapy.

 

What Are The Symptoms Of This Condition?

One of the earliest symptoms of gallbladder inflammation is abdominal pain. This is also known as biliary colic. This pain can also radiate to other parts of the body such as the back. More symptoms are listed below:

 

Are There Many Different Types Of Acute Cholecystitis?

Acute cholecystitis gallbladderThere are two main manifestations of acute cholecystitis, as discussed below in brief:

  • Calculous: This type arises as a result of physical obstruction of the cystic duct either by gallbladder stones or by biliary sludge. This is by far the more common type, accounting for an estimated 90% of all cases of acute cholecystitis. This type is less severe and is more easily treated.
  • Acalculous: Typically, this includes instances of acute cholecystitis that are not linked with gallbladder stones. This type is more severe and can worsen rapidly and even be fatal. It is often treated by means of surgical removal of the gallbladder. Causes range from physical trauma to chemotherapy. This type is also more common in individuals suffering from chronic diseases such as diabetes or HIV infection. The acalculous form of cholecystitis is less common and only accounts for about 10% of cases.

 

What Are Some Complications That Could Arise?

In 20% of cases, the inflammation becomes compounded by infection, usually of bacterial origin. Common pathogens responsible for gallbladder infections include Escherichia coli, Streptococcus and Clostridium, among others. The enlarged gallbladder is also at risk of becoming ruptured. Another possibility is that the enlarged organ may not receive enough blood supply, causing tissue to die and gangrene to set in.

 

Diagnosis, Treatment, & Prevention

acute cholecystitis liverEarly diagnosis is associated with a better overall outcome. If the disease is allowed to progress, the patient can develop severe complications that may result in irreversible organ damage. Diagnosis may involve the following procedures:

  • Physical examination. Sometimes the inflamed and swollen gallbladder is large enough to be felt upon palpation of the abdomen.
  • Medical history.
  • Blood tests.
  • Liver function tests.
  • Ultrasound imaging.
  • Computerised tomography (CT) or magnetic resonance imaging (MRI) tests.

In general, cholecystitis usually demands a hospital stay in order to control the inflammation of the gallbladder. In some cases, surgery might be required.

The treatment plan at the hospital might include the following:

  • Fasting– In order to reduce the stress on the gallbladder, drinking and eating might not be allowed initially (depending on the case).
  • Intravenous fluids– In order to keep you from dehydration, fluids are infused intravenously (through a vein in the arm).
  • Antibiotic course– In case of infection of the gallbladder, an antibiotic course is administered.
  • Pain reliever medications– These can help in controlling the pain and inflammation.
  • Endoscopic Retrograde Cholangiopancreatography (ERCP): This procedure is performed to remove the stones blocking the cystic duct or the bile duct.

The symptoms subside within 3 to 4 days. However, the inflammation might return. In such cases, gallbladder removal is advised.

  • Cholecystectomy– It is the procedure to remove the gallbladder. It is can be executed in two different ways. A minimally invasive procedure involves few small incisions in the abdomen. This procedure is known as laparoscopic cholecystectomy.  On the other hand, in the open procedure, a long incision is made. The flow of bile is directly from the liver to the small intestine once the gallbladder is removed.

Prevention of cholecystitis is mainly by sticking to a healthy diet and maintaining a healthy body weight and optimum cholesterol levels.

 

 

Facts

  • In the United Kingdom, gallstones affect around 1 in every 10 adults.
  • Females are more prone to acute cholecystitis as compared to males as the incidence of gallstones is more in females.

Facts

  • You can survive without a gallbladder.
  • In a day, the liver produces around 500 to 1000 ml of bile; the gallbladder can concentrate it up to tenfold and store 30 to 50 ml of the denser bile.

Facts

  • Gallstones are made up of cholesterol or bilirubin.

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Dos and Don'ts

Dos
  • Follow a healthy and balanced diet. It helps in preventing obesity. Obesity makes you prone to gallstones. A diet low in fiber and high in fats can also increase the risk of gallstones.
  • Exercise regularly to keep obesity at bay.
Don'ts
  • Go for crash diets for weight loss. Rapid loss of weight can augment the risk of having gallstones. Around 1 to 2 pounds a week is considered as a healthy weight loss.
  • Ignore symptoms such as abdominal pain, nausea, abdominal bloating, fever etc.
  • Indulge in smoking. Smoking can make your gallbladder prone to infections.

 

 

 

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Isagenix diet weight loss
How are BMI and BMR different and what do these numbers mean? BMI and BMR are two important metrics that provide a clear picture of your body's metabolism and also…
Optavia diet
The features of an Optavia diet The Optavia diet endorses pre-packaged meals and snacks called "fuelings" that are tasty, low in calorie, and incorporates…
dance health benefits
5 unbelievable effects of dance on your overall health! You enjoy dancing, but did you know what else it does to your body? Dancing is not only…
nutritional yeast bread
Nutritional Yeast : How can a fungi culture be good for your body? Nutritional yeast: How a simple culture of fungi can transform your skin, digestion, immunity , and much more.…
green poop causes
Green poop : What are the reasons and how can you correct it Ever sneak a peek down the toilet only to shockingly find green poop? Why does our poop turn…
What to eat, what not to eat in the South Beach Diet? The South Beach Diet is one among the most popular weight loss programs that have been the talk…
Mood swings
The real reasons for your mood swings and how to overcome them Are you prone to heated moods frequently? Do you also feel bouts of depressive feeling creeping up on…
Ear pain model
Easy and safe tips for ear wax removal you can do at home Cerumen impaction generally occurs when an external object like cotton swabs are used to remove the ear wax.…
CBC blood test
CBC (Hemogram 6-part diff) blood test CBC (Hemogram 6-part diff) blood test refers to the test that measures the number of RBCs, WBCs, etc…
BoneMarrow-Biopsy
Bone Marrow Biopsy Bone marrow biopsy is a diagnostic procedure where a small amount of bone marrow is extracted from hip…
beta hcg test
Beta hCG Test A Beta hCG test measures the level of human gonadotropin hormones present in the blood that is primarliy…
vdrl test syphilis
VDRL Test The VDRL test is a blood test that is used to diagnose sexually transmitted or venereal diseases, primarily…
blood ketone test
Blood Ketone (D3HB) Test The Blood Ketone Test measures and monitors the levels of ketone in the blood which is usually performed…
piles,fistula,fissures
Difference between piles, fissures, and fistula Click to know the difference between piles, fistula and fissure and the best ways to get effective treatment…
L-theanine attention
L-Theanine: Better sleep, higher focus, and many other benefits Did you know that L-theanine found in green tea can make you sleep better and be focused at…
Is it possible to achieve full body detox with Master Cleanse? Master cleanse is a diet consisting of a lemonade based beverage, a salt water drink and a herbal…
Vitamin b12
Vitamin B12 Test Vitamin b12 is an essential nutrient required for healthy functioning of the nervous system and also development of…
LFT-test
Liver Function Test – LFT LFT or Liver Function Test is a blood test used to determine the levels of hepatic enzymes which…
Hysteroscopy_procedure
Hysteroscopy Hysteroscopy is a minimally invasive tool to help specialists view the uterus to diagnose and even treat several…
C-Reactive Protein Test A CRP or c-reactive protein blood test is an important diagnostic tool used to determine the risk of…
Strep throat pain
Anti-Streptolysin-O Test The ASO or Anti-Streptolysin-O is a blood test designed to check for the presence of streptococcus bacterial infection…
myelogram
Myelography Myelography is an important diagnostic tool that is used to investigate and identify abnormalities in the spine and…
hidden causes obesity
8 hidden causes of obesity you probably didn’t know! Did you know that around 2 billion people worldwide are either overweight or obese? Are you too a…
about mediterranean diet
Why you should be adopting a Mediterranean style of diet today Ever wondered why the Mediterranean diet is so healthy? One simple solution to lowering risk of several deadliest…
Jicama: A fiber-rich tuber for your weight loss goals Pronouced as HEE-kah-ma, Jicama is the "new kid on the block" that has taken the world by the…
sugar toxic health
Sugar: 7 new shocking truths revealed about the sweet poison Can drinking soda bring you closer to death? Is sugar slowly poisoning you and your family? You would…
kefir bottle
Kefir: Top reasons why this probiotic drink should be consumed by you Yet another remarkable fermented food, kefir is a much healthier version of yogurt. These chewy white grains can…
Cayenne: The remarkable benefits of these red hot chili peppers These may make you rush for a glass of water, but cayenne pepper is actually a healthy additive…
Epley maneuver: Why is this the best protection from the symptoms of vertigo? Epley maneuver is an exercise that can treat the symptoms of benign paroxysmal positional vertigo (BPPV).  It was…