Lyme Disease

LYME DISEASE ticks

Last Updated December 20th, 2021

Overview

Humans acquire certain infectious diseases from animals. This process may occur through direct contact with infected animals or it may be mediated by vectors such as insects. Such diseases are known as zoonoses. Lyme disease is an example of a zoonosis.

It is usually transmitted to humans by certain hard-bodied ticks that feed on rodents infected with the bacterial pathogen responsible for the disease. If diagnosed in time, Lyme disease can be treated effectively. Otherwise, the patient may continue to suffer some debilitating symptoms in the long term. When allowed to go untreated, Lyme disease progresses to the heart and the central nervous system, in which case it can be fatal.

 

What is Lyme Disease?

LYME DISEASE ticksLyme disease is an infectious disease, usually caused by a bacterium known as Borrelia. Hence, it is also referred to as Lyme borreliosis. The pathogen is transferred to humans by means of a bite from ixodid ticks such as the black-legged tick or castor bean tick. These ticks acquire the bacteria from infected rodents.

Since they are only the vectors of the disease, the ticks themselves are not directly affected by the pathogen which breeds in their digestive tracts. Lyme disease is characterized by flu-like symptoms and often presents with a skin rash known as erythema migrans. In later stages, it can cause facial paralysis, inflammation of heart tissues and even cardiac failure.

 

What Causes It?

Lyme disease occurs as a result of a bite from a tick carrying certain bacteria belonging to the genus Borrelia, acquired from infected rodents. These ticks usually thrive in forested environments that are home to rodents and deer which are their preferred hosts. They are encountered among shrubs and low-lying vegetation, latching onto humans as they brush past. The bacteria are transferred into the human body via the saliva of the tick as it feeds on blood.

In the USA, Lyme disease is primarily associated with the Borrelia species B. burgdorferi and B. mayonii. Other species such as B. afzelii and B. garinii may also be implicated, especially in certain parts of Europe and Asia. Each species can produce a slightly different range of symptoms.

 

What are the Signs and Symptoms?

LYME DISEASEInitial onset is characterized by symptoms resembling those of the flu. Within a few days to a month of being bitten, a rash appears at the site of the tick bite. It begins as a small, red bump on the skin and subsequently enlarges. This may cause some itching or pain although the rash is more likely to be asymptomatic. Often, it takes a ringed form as it grows larger, resembling a bulls-eye sign. Rashes may also appear in other parts of the body. However, as many as 30% of patients may not develop rashes at all. A fuller list of associated symptoms follows below.

  • Fever.
  • Chills.
  • Swollen lymph nodes.
  • Profuse sweating at night.
  • Muscle pain.
  • Joint pain.
  • A skin rash, often showing a distinctive ringed shape resembling a bulls-eye sign.
  • Severe headaches.
  • Diarrhea.
  • Sleep disturbance.
  • Irritability and mood swings.
  • Stiff neck.
  • Back pain.
  • Facial paralysis.
  • Numbness or tingling sensation in the hands or feet.
  • Feeling short of breath.
  • Dizziness.

 

What are the Possible Complications?

In advanced stages, Lyme disease can produce severe joint pain and swelling. This is known as Lyme arthritis. Inflammation of the liver, or hepatitis, also occurs in some instances. Lyme carditis is another possible complication. This involves a disturbance in the electrical impulses responsible for regulating heart rhythm and can be fatal.

When the bacteria invade the central nervous system, they can produce numbness and facial paralysis. Another possible outcome is meningitis.
Advanced Lyme borreliosis also produces a skin condition known as acrodermatitis chronic atrophicans (ACA). The main agent responsible for this is B. afzelii. Hence, ACA is rarely seen in North American patients of Lyme disease and has been diagnosed more commonly in Europe.

 

Diagnosing Lyme Disease

LYME DISEASE rashA bulls-eye shaped rash also appears in connection with another tick-borne disease known as ‘southern tick-associated rash illness’ (STARI). This is caused by a bite from the lone star tick although the identity of the pathogen itself is as yet unknown. The habitats of the tick vectors implicated in both diseases can overlap. Therefore, diagnosis of Lyme disease cannot be made based solely upon the presence of the bulls-eye shaped rash.

A variety of rashes can appear in association with Lyme disease and these may even mimic rash produced by other insect bites or parasitic infections. The ticks that transmit Lyme disease are also known to spread other diseases like human babesiosis and human granulocytic anaplasmosis. Therefore, some patients with Lyme disease may also develop these conditions, further complicating the diagnosis.

Since initial symptoms are usually nonspecific, it is helpful if the patient themselves recalls being bitten by a tick or visiting an area known to be infested by the ticks responsible for transmitting Lyme disease. An enzyme-linked immunosorbent assay (ELISA) is used to detect antibodies produced by the immune system to combat the bacterial pathogen. If the result is positive, the diagnosis of Lyme disease is confirmed by means of a Western Blot test.

 

Treatment & Prevention

Lyme disease can be effectively treated with antibiotics if it is detected early. The antibiotic course takes 2-3 weeks to complete.  Most commonly prescribed antibiotics for Lyme disease are Doxycycline ( adults and kids above 8 years) and amoxicillin ( for younger kids and breastfeeding women). Lyme disease can be prevented by :

  • Covering your body completely when going camping or for similar outdoor activities.
  • Eliminate all possible elements that are conducive to tick growth. Clear wooded areas, regularly cut grasses and bushes, and don’t let waste accumulate.
  • Use insect repellents regularly and always check your pets for ticks.

 

Facts

  • 1 out of every 4 patients with Lyme disease in the USA is a child. Except for Antarctica, incidents of Lyme disease have been reported in every continent.
  • This infection is called the “great imitator” as the symptoms closely resemble other illnesses such as Lupus, Bell’s Palsy, Fibromyalgia, Arthritis, and Chronic Fatigue Syndrome.

Facts

  • It cannot be transferred from an infected person to a healthy individual. Also, not all ticks will give you Lyme disease.
  • The characteristic symptom of Lyme disease is a skin rash that looks like a bull’s eye though not every infected individual will show such a symptom.

Facts

  • Prior to 2002, there was a vaccine for Lyme disease but it was discontinued due to a scarcity of supply and also due to the fact that the potency of the vaccine decreased over time.

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Dos and Don'ts

Dos
  • Wear light-coloured clothes when going to marshy areas or forests so that if ticks attach to your body they remain clearly visible.
  • Always carry bug-repellent sprays when visiting such areas.
  • Keep your body fully covered, including your head when visiting areas with high tick density. Check the groin area, armpits, and thigh regions for ticks regularly.
Don'ts
  • Try to suffocate the tick by pouring hot wax or rubbing alcohol on the affected area.
  • Delay in seeking medical attention if you contract high fever and body ache just after returning from a camping trip.
  • Leave the treatment of Lyme disease midway as this could result in severe neurological conditions later.

 

 

 

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Anti-Streptolysin-O Test The ASO or Anti-Streptolysin-O is a blood test designed to check for the presence of streptococcus bacterial infection…
Unbelievable health benefits of gooseberries (and a few tasty recipes) Gooseberries are antioxidant-rich tasty fruits that can be easily added in daily diet to improve overall health and…
liver detox facts
7 liver detox facts and why ignoring these could kill you! Are you taking care of this organ that handles over 500 different vital functions in your body? Your…
L-theanine attention
L-Theanine: Better sleep, higher focus, and many other benefits Did you know that L-theanine found in green tea can make you sleep better and be focused at…
Oil of Oregano: The one-stop essential oil you’ve been looking for Are you plagued by a weak immune system? High body inflammation accompanied by pain and infections? Why not…
Valerian Root: The best way to achieve tranquil sleep every night Valerian root is probably one of the oldest and safest way to cure your insomnia. Find out how…
Did you know drinking alkaline water could be the healthier choice for you? Ever wondered how safe is your drinking water in terms of pH? Recent studies have revealed that Alkaline…
Kava: Is it the healthy substitute for alcohol you have been waiting for? Native to the beautiful South Pacific islands, Kava is a famous beverage rooted in the local culture. It…
Goji berry: A traditional Chinese berry that packs the best of antioxidants Goji berry is an ancient berry that is considered to be power-packed with nutrients and antioxidants. Which means…
The Cabbage Soup Diet: The healthiest way to instant weight loss Cabbage soup diet rapid weight loss diet for those who want to shed those extra pounds in less…
shakeology woman
Meal replacement or protein drink? Learn all about Shakeology and its claims Shakeology from Beachbody claims to be the most suitable shake that can aid in weight loss, regulate blood…
GGt test
GGT – Gamma-Glutamyl Transferase Test GGT or gammaglutamyl transferase test is a liver function test that is used to detect the extent of…
C-Reactive Protein Test A CRP or c-reactive protein blood test is an important diagnostic tool used to determine the risk of…
free psa test
Free PSA Test The free PSA test is used to detect the level or percentage of free PSA in the body…
Thyroid disorders
Thyroid Profile Thyroid profile is a panel of blood tests performed to check if an individual is suffering from any…
shiitake mushrooms healthy
What are Shiitake Mushrooms and why should you eat them? Shiitake Mushrooms are well known for their smoky and robust taste. However, did you know they are replete…
DHEA wrinkles
DHEA: Now get unbelievable age defiance with this wonder hormone! DHEA is known popularly as the age-defying hormone. This supplement is widely used to slow down aging and…
How seitan proved to be a blessing in disguise for vegans worldwide Can only meat-eaters enjoy delicious juicy steaks and burgers? With seitan, the best meat substitute available today,even vegans…
Surgery or home-remedy; what is the right way to treat a burn The treatment of a burn injury depends on its severity. You can save a life by offering the…
phenytoin test
Phenytoin test Phenytoin is a drug that is administered mainly to epilepsy patients. The phenytoin blood test measures the level…
asab antisperm antibody test
Antisperm Antibody Test The ASAB or anti-sperm antibody test is a blood/semen test that analyzes the level of sperm-killing antibody protein…
AHBC Igm
Anti-Hepatitis B Core Antigen (AHBc) IgM Anti-hepatitis B core antigen (AHBC) IgM is an investigative procedure to detect the presence of IgM antibodies in…
hidden causes obesity
8 hidden causes of obesity you probably didn’t know! Did you know that around 2 billion people worldwide are either overweight or obese? Are you too a…
lose weight fast
12 easy and instant steps to successful weight loss Do you want to lose weight without losing your mind? Does weight loss always mean saying goodbye to…