Becosules

Therapeutic indications

Becosules is used as a multivitamin that is indicated for various conditions that include acne, hair loss, anemia muscle cramps, and diarrhea. It is also used to treat Vitamin B12 deficiency and high cholesterol and triglyceride in the blood. The drug is also used to treat conditions where for dietary deficiencies where one is unable to obtain sufficient food intakes. Specific conditions for which this drug is prescribed include the following:

• Oral ulcers
• Hepatobiliary tract disease
• Glossitis
• Stomatitis
• Cheilosis
• Alopecia
• Acne
• Conditions that cause poor dietary intakes such as alcoholism, diabetes, obesity and aged people
• Metabolic conditions that cause an increase in dietary requirements such as febrile illness, fever, chronic infections, post-surgery, burns, and fractures
• Poor nutrient absorption and assimilation due to diarrhea, malnutrition or rapid weight loss.
• Anemia that can be caused by Vitamin B12 deficiency, nutrition deficiency, pregnancy or infancy or lack of adequate folic acid in the body
• General deficiency of several vitamins such as B12, B3, folate, biotin, A or C.
• Heart diseases
• Hypophosphatemia and hypocalcemia
• Mental disorders
• Osteoarthritis
• Arthritis
• Alzheimer’s
• Weak nails
• Skin and hair growth
• Migraines
• High cholesterol
• Alopecia
• Muscle cramps
• Scurvy
• Seborrheic dermatitis
• Folate deficiency
• Uremic osteodystrophy
• Congenital
• Loss of hair
• Greying of hair
• Supplements
• ADHD
• Salicyclate toxicity
• Clogging of arteries
• Catarrhal respiratory disorders
• Congenital hypothyroidism
• Streptomycin neurotoxicity
• Mental disorders or cognitive disorders
• Seborrheic dermatitis
• CVD
• Diabetes
• Hypophosphatemia
• Corns

There are possibly other indications for which this drug used and which may not be included in the list above. It is also used for:

• Promotion of growth of red blood cells
• Improvement of the health of cells
• Improves the health of the brain
• The increase in energy levels
• Promotion of eyesight
• Promotion of healthy appetite
• Improvement of good digestion
• Proper maintenance of cholesterol production in the body
• Improvement of nerve functions
• Promotion of cardiovascular health
• Boosting of immunity
• Repairing body tissues (Vitamin C is used for this purpose).

Becosules is prescribed for a variety of symptoms. It is crucial to identify the underlying cause to get that treated. There are various blood tests and scans available to check your health paramaters. These will help you make an informed decision about your course of treatment. This will also let your doctor advise you what other medications need to be taken along with Becosules.

Some tests that are recommended to be carried out are CBC blood test to check your complete blood count panel, vitamin B12 blood test to check if you have vitamin B12 deficiency, lipid profile blood test to check your cholesterol levels, TSH blood test to check your levels of TSH (thyroid-stimulating hormone), and bone density test to check for osteoarthritis.

Do I need a prescription?

Becosules is prescribed for different conditions for different patients. Only a doctor can examine and prescribe the right dosage for diagnosed condition and depending on the medical history of a patient. Do not take over the counter without a medical prescription.

Chemical composition

The drug has the following active ingredients:

Other active ingredients include the Ascorbic acid, Riboflavin, Thiamine and Vitamin 12.

Mechanism of Action (MOA)

The drug is designed to trigger megaloblastic to produce megaloblastic bone marrow which in turn treats vitamin B12 deficiency in the body, lowers blood cholesterol level in the body as well as triglyceride levels, which is results from prevention of synthesis of low-density proteins.

This action of production of normoblastic marrow also results in the prevention of damage of cells from peroxidation due to high levels glutathione. It also modifies electrical nerve activity, which reduced the activity of heart muscles and provision of ascorbic acid in the body which are used in doing a reversible reaction of oxidizing dehydroascorbic acid.

Becosules is also used in reducing production of prostaglandin that is useful in the prevention of blood thinning, hence preventing clotting of blood in the body; the relaxation action of nerve signals in the brain is also one of the actions of this drug in the body. It is taken to treat and prevent a lack of sufficient biotin in the body.

Becosules is used to restore metabolic reaction in the body to normal. Different vitamins in the drug act for different functions. The drug helps the body to metabolize carbohydrates and alcohol better. Folic acid is used to help synthesize nucleoprotein synthesis and normal erythropoiesis.

Vitamin C, a constituent in Becosules is used for oxidation and reduction reactions in the body and in the synthesis of lipids and for better functioning of carbohydrates and blood vessels.

Contraindications

These are the unintended effects of the drug. They may occur as a reaction after taking Becosules. Adequate attention is needed.

• Allergic reactions
• Intolerance to drugs
• Heightened mast cells
• Leber’s disease
• Hypersensitivity or allergic reactions

Side effects

Less serious and common side effects include:

• Headaches
• Mild and momentary diarrhea
• Cramps
• Itching
• Hives
• Bitter or bad tastes in the mouth
• Sore throat
• Unexplained tiredness
• Eczema
• Disturbed sleep
• Interrupted sleeping patterns
• Dizziness
• Weakening of muscles
• Entire body swelling
• Nausea
• Gas
• Irritability
• Confusion
• Seizures
• Temporary faintness
• Dryness of mouth
• Constipation
• Leg pains
• Hives
• Lungs may swell
• Chest pains bloating
• Allergic reactions
• Bloating

Serious side effects that are less common include:

These side effects are rare but can be deadly. It is recommended to seek medical assistance as soon as possible and more especially if these symptoms persist.

• Congenital heart problems
• Frequent feeling of need for urination
• Dry hair
• Dizziness
• Skin rash
• Allergic reactions
• Diarrhea
• Excessive thirst
• Change of urine color
• Cephalgia
• Poor focus
• Stomach distention
• Anorexia
• Ulcers
• Overactivity
• Nausea
• Flatulence
• Poor concentration
• Fretfulness
• Swelling of lips and tongue
• Breathing difficulties
• Liver toxicity
• Face stiffness
• Unexplained increase in weight
• Impaired judgment
• Swelling
• Heartburn
• Dyspnea
• Heart failure
• Pruritus
• Cyanosis
• Pain or swelling at the site of injection
• Fibrosis, which may cause blood vessels to block
• Restlessness
• Numbness due to dysfunction of nerves
• Declined vitamin B12 in serum
• Reduced or failure of bile secretion in small intestines
• Urge to vomit

Drug Interactions

These are food, conditions or drug substances that may react or interfere with expected or normal therapeutic effects of the drug in the body. These include the following:

• Alcohol
• Anti-diabetic drugs
• Aminophylline
• Allopurinol
• Arsenic trioxide
• Abacavir
• Allopurinol
• Atropine
• Barbiturates
• Bishydroxycoumarin
• Atorvastatin
• Bishydroxycoumarin
• Carbamazepine
• Chloramphenicol
• Chlorothiazide
• Chlorpromazine
• Chlorthalidone
• Cholestyramine
• Clonidine
• Clozapine
• Desogestrel
• Digoxin
• Diphenylhydantoin
• Dolutegravir
• Doxorubicin
• Erythromycin
• Ethinyl Estradiol
• Fluvoxamine
• Folic acid
• Furosemide
• Gabapentin
• Glycopyrrolate
• Haloperidol
• Hydrochlorothiazide
• Hydrocortisone
• Imipramine
• Iron Salts
• Isoniazid
• Lamivudine
• Levodopa
• Levonorgestrel
• Levothyroxine
• Lisinopril
• Mestranol
• Methotrexate
• Methylamphetamine
• Mexiletine
• Nafcillin
• Nitrofurantoin
• Olanzapine
• Oral contraceptives
• Paracetamol
• Penicillamine
• Pentazocine
• Phenobarbital
• Phenothiazine
• Phenytoin
• Primidone
• Probenecid
• Propranolol
• Pyrimethamine
• Raw egg white
• Rutin Vitamin P
• Scopolamine
• Sodium Bicarbonate
• Sodium Succinate
• Sulfinpyrazone
• Sulphadiazine
• Tacrine
• Tetracycline
• Tetracyclines
• Theophylline
• Tricyclic antidepressants
• Valproic acid
• Zileuton
• Zolmitriptan

What to Do If You Skip a Dose

Ensure to take the usual dose as advised by an informed doctor aware of your condition. If you forget, take the missed dose as soon as you remember. However, you should avoid taking this dose if it about time to your next dose. Never take an additional dose. Frequent misses might make the drug ineffective.

Dosage

Typical dosage is one tablet or capsule daily, taken with or after food but this varies with patient’s condition. Any change of this dosage can only be done after consulting with a doctor depending on the assessed condition of a patient.

There is no single mass of the capsule or tablet. They vary and have been packed in the following categories:

• Becosule 100mcg
• Becosule 15mcg
• Becosule 1.5mg
• Becosule 3mg
• Becosule 10mg
• Becosule50mg
• Becosule 100 mg
• Becosule 150mg

As indicated in the variations above, there is no single dosage of the drug; they are prescribed depending on the condition of a patient. These forms are prescribed for different conditions.

Precautions

• Pregnant or breastfeeding women should consult a doctor before taking this drug unless advised so by a doctor. Folic acid and Thiamine (vitamin B12) can be taken but consult a doctor). Do not take these before seeking medical advice: niacinamide, riboflavin, ascorbic acid, pyridoxine, biotin, and calcium pantothenate.
• You should inform if you are taking any vitamin or herbal supplements that are bought over the counter
• You should inform a doctor if you are having other medical problems that may interfere with the medication or causing other known side effects
• Take the dosage as per the instructions of the doctor. Don’t overdose, under-dose or change time allocated by the doctor
• Do not take Vitamin 12 through Becosules capsules for pernicious anemia or any other megaloblastic anemias where vitamin B12 is deficient
• Take caution if you are undergoing anticoagulant therapy
• Do not take alcohol while undergoing this therapy. It is especially critical if you are having alcoholic cirrhosis. Alcohol also causes increases in drowsiness side effects.
• When taking niacin, avoid taking alcohol
• Inform your doctor if you are breastfeeding
• Inform your doctor if you have diabetes
• Do not take this medicine on an empty stomach
• Becosules can cause false lab tests. Known cases are of glucose tests
• Take care to not expose drugs to excessive sunlight
• Do not take this drug with steroids
• Inform your doctor immediately if you have numbness or tingling sensation
• When administering via IV, ensure this process is not hurried.
• You may operate machinery and drive after taking Becosules but you should stop immediately if you experience any symptoms of dizziness. headaches or drowsiness
• Consult a doctor if this medicine can be tapered or if they can be stopped immediately. This depends on side effects, interactions and nature of the patient’s condition.
• Ensure to take foods to nourish and replenish food with essential vitamins. Vitamins alone are not enough
• Do not take more than the recommended dose for this drug. Overdose for any reason of this drug and any other iron-containing products can fatally poison children under 6. A noted or suspected case should be reported to a doctor immediately
• Ensure to take the drug orally and not in any other way as instructed by a doctor
• Check the expiry date of the drug before taking this drug. Do not take expired drugs
• Becosules are water soluble and in case of an overdose, they do not cause excessive effect as they can be excreted by kidneys. However, in the case of kidney disease, this excretion can fail and can accumulate in the kidney.
• Aged or elderly people are not advised to take this medicine without first consulting a doctor
• People with kidney problems should inform a doctor first
• If you are allergic to cobalt, do not take this drug without consulting with a doctor first

There are other precautions that are taken due to individual constituents of Becosules. Each of them may have individual precautions are included below:

For Ascorbic acid:

• Inform a doctor if you experience kidney stones
• Diabetics are also advised to seek medical advice before taking the drug. They may need to take a urine test for sugar before taking the drug
• Breastfeeding is not recommended before seeking medical advice

For Vitamin B9 or folic acid, do not use if you are diagnosed with megaloblastic, pernicious or ablastic anemia.

Substitutes of the Drug

Several products of the same strength and form are manufactured by different companies. Some of these include the following:

• Optisulin Cap
• Becosules Syrup 60ml
• Sioneouron Forte Tab
• Becosules Syrup 120ml
• Becosules Syrup 120ml
• Nutrolin B Ped Tabs 10s
• Cobadex Forte Cap 15s
• Cobadex Forte Cap 15s
• Cadbe Drops 15ml
• Riconia Drops
• Cecure Cap
• Vitamin Z Tab 10s
• Visyneral Oral Drop 15ml

There are many other substitute drugs for Becosules that are not listed above. Availability depends on the location of the manufacturer.

Facts and recommendations

Statistics from people that bought this drug from one source used it for various conditions as indicated below:

• Acne 23%, Hair loss 15%, Vitamin B12 Deficiency 10%, Hair fall 10%. The rest had less than 10% and they included Supplements 6%, Gray hair 5% Muscle cramps 5%, Vitamin deficiency, Alopecia, Diarrhea, and high cholesterol all had a rating of 4%.
• For various conditions, users that rated it as effective were 76% while 24% noted otherwise.
• Most people used it after meals and the least took it for before food.
• The medicine can be given to children although medical supervision is recommended
• There are no reports on the effects of pregnant or breastfeeding mothers although it is safer to seek doctor’s opinion
• The drug is available over the counter (OTC) but as indicated, a doctor’s opinion for a diagnosed condition is preferred.

References

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