Last Updated December 20th, 2021

Therapeutic indications

Bifilac is a capsule that contains live micro-organisms that are good bacteria that replenish the gut microflora. It is a probiotic and used as a dietary supplement. It is used for the management, control, and treatment of the following conditions, symptoms, and diseases:

  • Diarrhea due to antibiotic use
  • GERD stomach burn
    Gastrointestinal disorders such as gastroenteritis, colitis
  • Diarrhea
  • Constipation
  • Indigestion
  • Lactose intolerance
  • Lowering serum cholesterol levels
  • Irritable bowel syndrome and inflammatory bowel syndrome
  • Building immunity
  • Travelers diarrhea
  • Rotaviral diarrhea
  • Bacterial infections
  • Vaginal infections such as yeast infections, bacterial vaginosis
  • Acne
  • Aphthous ulcer
  • Gastric disorders
  • Bloating
  • Dry, scaly skin( mild to severe forms)

While Bifilac helps restore the gut microbiome, it is advisable to get a health checkup done to determine the cause of your health problems. For example, vitamin B12 deficiency can lead to problems like bloating, gas, constipation or diarrhea.

A simple blood test done at home can check your vitamin B12 levels and help your doctor determine the cause and follow the most effective course of treatment. We have outlined the complete procedure and how to prepare for a vitamin B12 blood test and for a CBC blood test, a very commonly prescribed test to check your complete blood panel.

Since Bifilac is also taken to manage cholesterol levels, it is advisable to do a lipid profile blood test to get a detailed cholesterol analysis of your blood.

Do I Need a Prescription?

Bifilac can be bought from pharmacies close to you and online drug stores. It is an over the counter medication and does not require a prescription to be purchased.


The dosage for Bifilac is depended on the severity of the condition being treated and age. The recommended dosage for Bifilac is one tablet or two tablets in a day. The tablets should be taken with food to avoid stomach upset. If you are taking more than one tablet, they should be spaced evenly during the day.

Chemical composition of bifilac

Bifilac is a probiotic and the active ingredients are live bacteria that include:

  • 50 million spores of Lactobacillus sporagenes
  • 30 million spores of Streptococcus feacalis
  • 2 million spores of Clostridium butyricum
  • 1 million spores of Bacillus mesentercus

Mechanism of Action (MOA) of bifilac

Bifilac contains live micro-organisms that when taken replenish the good microorganisms that are killed by taking antibiotics. Having healthy organisms in your gastrointestinal tract prevents one from contracting some diseases. When there is an imbalance in the microflora, one contracts some diseases. Taking antibiotics to treat bacterial infections kills both the pathogens and the good microorganism creating an imbalance. Bifilac has good bacteria that are pure and have been isolated. Thus when taken it causes their repopulation leading to a healthy microflora. Increase in the number of good bacteria also causes competition with the pathogenic bacteria resulting in their death. This results in disease prevention and building if the immune system to prevent future infections.

Facts on Bifilac

  • Bifilac is at times prescribed together with antibiotics to prevent and control the effects of the antibiotics like ulcers and diarrhea
  • Bifilac should not be used together with medications that suppress your immune system working.
  • Bifilac may also enhance the absorption of nutrients from the gastrointestinal tract.
  • Although Bifilac is an over the counter medication, consult your, doctor, before you can begin using it, thus should be used with medical supervision.
  • Bifilac does not cause drug dependency in patients.
  • The effects of Bifilac should be experienced either on the same day or during the first few days of your treatment.


The use of Bifilac is not advised if you have some medical conditions. Taking this medication with the conditions may worsen the condition you are treating or cause toxicity resulting in adverse reactions. Inform your doctor of all medical conditions you are suffering from or have had before to as it might affect the prescription from your doctor. The following medical conditions are contraindicated:

  • Allergic reaction: Do not take Bifilac if you are allergic to any of the active ingredients.
  • Any kind of hepatic impairment
  • Any kind of renal disease
  • Pregnant women. Bifilac should only be used if the benefits outweigh the risks to the growing fetus
  • Breastfeeding mothers. It should not be used unless the benefits outweigh the risks to the nursing baby
  • Intolerant to the medication
  • Diarrhea accompanied by a high fever
  • Weakened immune due to HIV infection or chemotherapy

Side effects

Medications can cause side effects apart from the intended good effects. Bifilac also causes some side effects. The side effects do not occur in everyone as they depend on the dosage and individual reaction to the medication. Some of the side effects go away on their own on the course of therapy. The side effects that occur can be minor and common while others can be major and rare. Report any side effects you experience to your doctor to get medical advice on how to manage them. The following are the side effects of Bifilac that have reported:

  • Redness of skin
  • Redness of mucous membranes
  • Stinging on application
  • Irritation
  • Burning
  • Gas
  • Stomach pain
  • Diarrhea
  • Dizziness
  • Colic pain
  • A headache
  • Constipation
  • Flatulence
  • When used vaginally it can cause vaginal irritation
  • Nausea
  • Vomiting
  • Acute toxicity
  • Skin Rashes

If you suffer an allergic reaction to Bifilac, discontinue its use and report it to your doctor or immediately seek medical attention. Allergic reactions when left unattended could turn fatal. Signs of an allergic reaction to Bifilac include:

  • Swelling of the lips, face, throat, and tongue
  • Difficulty breathing and swallowing
  • Rashes
  • Itching

If you accidentally take an overdose of Bifilac, inform your doctor or rush into the emergency center of the nearest hospital carrying the medication package with you for identification. Taking of an overdose could cause toxicity resulting is a bad reaction to the medication. An overdose may cause difficulty breathing, fever, itching swelling of the throat, lips, and face, itching and seizures.

Drug interactions


Taking more than one drug at the same time is likely to cause drug interactions. Drug interactions may change the working if your medication of the other drugs, it may affect the absorption from the gastrointestinal tract and elimination of your medication from your body that may cause adverse reactions to occur. To avoid drug interactions from occurring, inform your doctor of all medications you are using including both prescription medications and over the counter drugs, dietary supplements, and herbal products. The following drugs and products are known to interact with Bifilac:

  • Antibiotics
  • Cyclosporine
  • Azathioprine
  • Basiliximab
  • Immunosuppressant
  • Alcohol
  • Antifungals

What to Do IF You Skip a Dose

If you skip a dose, take it as soon as you realize it. If it is close to the time for your next dose, you can skip it and take your next dose then continue with your regular schedule. However, do not double the dose to compensate for the skipped dose as it could result in toxicity due to the high dose. Frequent missing of doses makes your medication less effective in treating your condition. To avoid missing of doses, set the alarm or have a family member remind you when it is time for your next treatment.


Some precautions should be considered before and while using Bifilac. The precautions include:

  • Hypersensitive reactions: Do not use Bifilac if you are allergic to any of active ingredients.
  • Inform your doctor of all medications you are using or have been using previously to avoid drug interactions.
  • Inform your doctor of all medical conditions you have including those you have a history.
  • Avoid the use of antibiotics while you use probiotics as Bifilac contains bacteria that might be killed by the antibiotics.
  • Avoid the use of alcohol while you are using Bifilac, it could increase drowsiness.
  • Diabetics should use Bilifac with cautions, more so the chewable tablets or powders as they may have sugar or aspartame.
  • Bifilac should be used in pregnancy with caution when the benefits outweigh the risks.
  • Bifilac is not known to cross into breastmilk but should be used with caution in breastfeeding mothers.
  • In the case that you experience dizziness while using Bifilac, do not take part in activities that require mental alertness such as driving and operation of heavy machinery.
  • Bifilac should be stored at room temperature away from sunlight and heat. Also, it should be stored away from pets and children.
  • Do not take Bifilac that is expired. Expired medication may not be effective in treating your condition. Always check your medication for the expiry date during purchasing.
  • Do not stop taking your medication when you get a relieve from your symptoms. Take the medication for the duration prescribed to prevent the symptoms from recurring.
  • Bifilac should be used with caution in individuals with liver diseases and renal diseases.
  • If used by infants, do it with the strict observation from your pediatrician.
  • Do not take Bifilac for longer than the duration recommended by your doctor. If you do not experience an improvement in your symptoms or they get worse consult your doctor immediately for re-evaluation.
  • Bifilac should be taken with food or immediately after a meal to avoid stomach upset.
  • Take the tablets or capsule as a whole, without crushing or chewing.

Brand Names and Manufacturing Companies of the Drug

Bifilac is manufactured by Tablets India Limited. It comes in different forms that include tablets, lozenges, sachets, and syrup. Tablets India also manufactures the following products:

  • Bifilac capsule/ 0.5 sachet that contains 50 million spores of Lactobacillus
  • Bifilac Dry 50 ml syrup that contains 1 million cells Bacillus mesentericus, 2 million cells Clostridium butyricum, 50 million cells Lactobacillus sporogenes and 30 million cells Streptococcus thermophilus
  • Bifilac lozenge that contains 1 million spores Bacillus mesentericus, 2 million spores Clostridium butyricum, 50 million spores Lactobacillus sporogenes and 30 million spores Streptococcus thermophilus
  • Bifilac Hp capsule that contains 100 million spores Lactobacillus
  • Bifilac Zn 1 gm sachet that contains 1 million spores Bacillus mesenterics, 2 million spores Clostridium butyricum, 7 mg elemental zinc, 50 mg L-glutamic acid, 50 million spores Lactobacillus, 30 million spores Streptococcus thermophiles
  • Bifilac Lozenges 15S tablet that contains 1 million spores Bacillus mesentericus, 2 million spores Clostridium butyricum, 50 million spores Lactobacillus, 30 million spores Streptocccus thermophilus

Substitutes if the Drug

Alternatives that can be used in place of Bifilac with the same composition and strength include:

  • Bio 4 – Tablets India Limited
  • Becelac PB – Dr. Reddy’s Laboratories Ltd
  • Vi-Gut – Lifeon Pediatrics Limited
  • Gutpro Powder – JB Chemicals & Pharmaceuticals Limited
  • Cyfolac capsule – Karnataka Antibiotics & Pharmaceuticals Limited
  • Rexflora capsule – Kontest Chemicals Limited
  • Vizylac capsule – Unichem Laboratories Ltd
  • Becelac Fortz capsule – Dr.Reddy’s Laboratories Ltd
  • Darolac capsule – Aristo Pharmaceuticals
  • Cadbios capsule – Cadila Pharmaceuticals
  • Pro Wel capsule – Alkem Laboratories

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