Anemia

Anaemia woman

Last Updated October 23rd, 2019

Overview of Anemia 

The prevalence of anemia is the highest in India. At present nearly 50% of India’s population suffers from some form of anemia. A recent survey by the National Institute of Health has revealed that nearly 74% of the pregnant women in India suffer from the disease.

On a regular basis, we come across people who are apparently strong and healthy but are medically not fit. These people suffer from multiple deficiencies like pale skin, breathlessness, muscle cramps, fatigue, frequent palpitation, and sluggishness. These are inevitable symptoms of a hemoglobin deficiency disease namely “anemia”. Due to less severity of the disease at a primary stage, people usually neglect diagnosis and treatment. But when the disease persists for a prolonged period of time, the damages caused to the body are irreparable. According to the records of Center for Disease Control and Prevention (CDC), nearly 48 % of infants, 25 % of school children and 42% of pregnant women are victims of this disease worldwide.

What is anemia?

Anemia is the pathological condition in which the red blood cell (RBC) count drops in blood. This, in turn, leads to hemoglobin deficiency and subsequent lack of oxygen supply to blood.

What causes anemia?

Anaemia nailsThere are numerous etiological factors behind anemia. Listed below are few clinical conditions that predispose the body to the disease –

  • Iron deficiency: Shortage of iron in the body occurs mainly due to lack of iron (Fe) containing nutrients in the regular diet. Presence of permanent ulcers or cancerous cells within the body is a prime contributor behind Fe deficiency. Individuals suffering from Celiac disease have damaged intestinal walls (inner lining of the small intestine) which lead to acute “iron absorption” failure by the small intestine. This causes a deficiency of iron in the body. In women, monthly loss of blood due to menstruation causes iron deficiency at puberty. Shortage of iron in the body impedes hemoglobin formation by the bone marrow, which leads to a reduced percentage of Red Blood Cells (RBC) in blood.
  • Vitamin B12 deficiency: Vitamin B12 is essential for the formation of Red Blood Cells. Deficiency of either Vitamin B12 or Folate compounds in regular diet can equally contribute towards anaemic symptoms. 

What are the major warning signs ?

Anaemic symptoms are often overlooked due to lack of knowledge or attention. The following symptoms are critical indicators of the disease at different stages-

  • The skin turns pale or a sick yellow
  • Frequent muscle cramps
  • Breathlessness after slight physical activities
  • Extreme exhaustion
  • Profuse sweating and increased thirst
  • Frequent headaches
  • Lethargy throughout the day
  • Irregular heart rate (palpitation)
  • Frequent mood swings and irritability
  • Nausea

What are the different categories?

Anaemia womanAlthough iron-deficiency induced anaemia is the most common form, there are three other types of anaemia people need to be aware of. All categories have been elaborated below:

Iron deficiency Anaemia: During certain clinical conditions the body needs more iron than usual to synthesize hemoglobin that supports the RBC. On various occasions, low intake of iron in daily food items, excessive drainage of iron from the body due to menstruation or pregnancy causes an increased demand for iron in the body. When this demand is not met, acute iron deficiency occurs resulting in anemic conditions.

Vulnerable groups

    • Women in their adolescence or during pregnancy period
    • Children lacking proper diet
    • People affected with Crohn’s symptoms, Celiac disease or renal failure
  • Patients having internal injury and hemorrhage

Pernicious Anemia: This disease occurs due to the deficiency of either Vitamin B12 or Folic acid derivatives in the body. This condition arises when the body lacks a particular protein called Intrinsic Factor (IF) which helps to extract Vitamin B12 from the nutrients in the daily diet. 

Vulnerable group: People lacking meat, egg and dairy products in their regular diet

Aplastic Anaemia: This is a relatively critical form of anemia which encompasses three distinct conditions –

    • A drastic drop in the count of RBC (anaemia)
    • Reduced platelet count (thrombocytopenia)
    • Drop in White Blood Cells count(Leukopenia)
  • These three conditions are collectively called pancytopenia.

Vulnerable group: Cancer patients undergoing chemotherapy or radiotherapy

Haemolytic Anemia: This is the rarest form of the disease where normal RBCs die much before their usual lifespan (120 days), but the body cannot instantly cover up for those RBCs by forming new RBCs. Hemolytic Anemia is further subdivided into two types: Acquired Hemolytic Anaemia and Inherited Hemolytic Anaemia.

Vulnerable Groups: Any person can develop this disease depending on their environment and genetic pattern.

What are the long-term systemic effects?

Long-term effects of Anemia, especially the one caused by iron deficiency is perceived at a much later stage and are usually irreversible in nature. Following are the long-term and permanent effects experienced by chronic anemic patients:

  • Cognitive disorders in the form of disturbed behavioral and physical growth patterns are observed in growing children
  • A permanently damaged immune system is evident in all age groups exposed to anaemia for a considerable period of time
  • Deterioration in muscle activities takes place which eventually leads to decreased productivity
  • Prenatal risks are increased manifold
  • Infant mortality rates might be escalated

Is there any hereditary factor?

Flemming et al of the Harvard Medical School research team has discovered a particular mutated gene called TMPRSS6 that triggers iron deficiency causing different degrees of anemia. Again, deficiency of TMPRSS6 protein spurs the formation of excess hepcidin hormone that prevents effective iron absorption by the intestine. Hence it is clear that gene has a distinct role in this case.

Treatment and prevention

Anaemia foodTreatment options for anemia include:

  • Iron tablets and supplements which can be taken at empty stomach (if they don’t cause any digestive disorders). These are generally taken over a period of several months.
  • Improve dietary habits and include iron and folate-rich foods in your diet such as spinach, kale, broccoli, dry fruits and nuts, and liver.
  • Consume citrus fruits and juices that contain vitamin C, along with iron supplements to aid better iron absorption.

Preventing anemia involves:

  • Consuming an iron and folate-rich diet especially for pregnant women.
  • Breastfeeding women should also keep their hemoglobin level on a check. Infants should be breastfed properly and/or given iron-fortified milk formula.
  • Menstruating women and frequent blood donors should also monitor their hemoglobin level and keep consuming iron-rich foods.

Facts

  • Iron is not the only essential nutrient whose deficiency can cause anemia. Vitamin B12 deficiency or folate deficiency can also result in anemia.
  • Due to a lack of EPO of erythropoietin, people on dialysis often tend to become anemic. EPO is produced by healthy kidneys.

Facts

  • Young women are at the highest risk of getting anemia. This is majorly because of monthly menstrual cycles. People who are frequent blood donors are also at risk.
  • In a healthy human body, RBCs live for up to 120 days after which they are systematically replaced by bone marrow, spleen, and the liver.

Facts

  • Infants who are born pre-term and/or have low birth weight also have reduced RBC count. C-section babies are also anemic during the neonatal stage.

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Dos and Don'ts

Dos
  • Consume a diet rich in iron and vitamin B12. These are abundantly available in spinach, liver, legumes, shellfish, and quinoa.
  • Get an adequate amount of vitamin C from your diet as well. Vitamin C aids in iron absorption.
  • Maintain proper hygiene and sanitation to protect yourself from infections as anemia directly reduces one’s immunity.
Don'ts
  • Consume tea, coffee, or aerated cola drinks with meals as these tend to decrease iron absorption in the body.
  • Eat calcium-rich foods/ calcium supplements along with iron supplements as these tend to reduce iron absorption.
  • Worry if your stools appear slightly darker when taking iron supplements. But do consult doctor if constipation occurs and persists.

 

 

 

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Beware of these common foods that cause high bodily inflammation! Maybe its the long list of inflammatory foods in your diet that is making you frequently sick. Find…
Find all the instant ways to get rid of blackheads Blackheads - Not only are they aesthetically unappealing but if left untreated these can cause bacterial overgrowth on…
How to correctly perform nasal irrigation using a Neti Pot? Neti pot has been a part of Ayurveda since centuries. This ancient tool is extremely effective in treating…
Oxalates: How healthy greens can sometimes be bad news for your kidneys Oxalates are compounds present in a majority of healthy foods. However, at times an overconsumption of these could…
SIBO Diet: The important dos and don’ts of this gut-healing diet A SIBO diet is a diet that works by eliminating certain sugars from your diet and adding fibers…
11 unbelievable health benefits of thyme you didn’t know! Thyme is a herb that has been used in alternative medicine.It is a well known seasoning in the…
Coffee Enema: Turn your favorite morning beverage into a powerful colon cleanser The wonders of coffee are not just limited to waking you up every morning. You can now use…
reflexology massage
Top reasons why you should go for a reflexology massage today Reflexology involves the application of pressure to your feet and hands to encourage self-healing. Could this be beneficial…
GGt test
GGT – Gamma-Glutamyl Transferase Test GGT or gammaglutamyl transferase test is a liver function test that is used to detect the extent of…
iron deficiency profile
Iron Deficiency Profile An iron deficiency profile is a battery of blood tests which are performed in order to determine the…
ureteroscopy
Ureteroscopy Ureteroscopy is the diagnostic procedure which is used for the detection of the kidney stones in addition to…
quinoa salad
Quinoa : A prodigious superfood you need to include in your diet today! Quinoa - what is so special about this native South American grain that has taken the world by…
L-theanine attention
L-Theanine: Better sleep, higher focus, and many other benefits Did you know that L-theanine found in green tea can make you sleep better and be focused at…
improve digestion weight loss
Power up your gut: 8 proven steps on how to improve your digestion Did you know you have a colony of bacteria in your gut that help you in digesting food?…
avocado benefits
Avocado: 15 reasons why this fruit should be a staple in your diet Did you know that the word avocado literally means "testicles". Don't get grossed out as this power-packed fruit…
bananas exercise
10 health reasons why you should go “bananas” over bananas! Bananas:The world's most popular fruit comes with a host of unbelievable health benefits. Find out how you can…
ashwagandha brain
Ashwagandha: The best-kept secret of Ayurveda now revealed! Ashwagandha literally means "smell of horse". Don't get bogged down by that one tiny detail because this ayurveduic…
Coconut sugar: What is it and is it healthier than table sugar? In the long list of things that the wonderful coconut gives us, coconut sugar is another remarkable addition.…
The right way to prepare Alfalfa sprouts at home Alfalfa or lusan ghas is not just a nutritious animal fodder. This flavonoid-rich herb has some amazing health…
Pescatarian Diet 101: What are the inherent health advantages of this diet? People opt to become a pescatarian in order to enrich their bodies with the essential health benefits that…
How to scrub away stress and fatigue with an Epsom salt bath? Epsom salt is a popular home remedy for many skin ailments. Though there is a lack of scientific…
thyroid_scan
Thyroid Scan Thyroid scan is a diagnostic procedure that aims to view the thyroid gland and detect any growths or…
vdrl test syphilis
VDRL Test The VDRL test is a blood test that is used to diagnose sexually transmitted or venereal diseases, primarily…
lp-pla2
LP-PLA2 Test The LP-PLA2 test is a test which is carried out to assess the levels of Lipoprotein-Associated Phospholipase A2…
complement c4 test
Anemia Profile Anemia Profile test (Basic) is a blood screening test that measures the levels of important components of the…
shoudler exercises
Keep your shoulders pain-free with these shoulder exercises Shoulder exercises are important in order to prevent chronic back and neck pain. Learn more about how you…
sugar toxic health
Sugar: 7 new shocking truths revealed about the sweet poison Can drinking soda bring you closer to death? Is sugar slowly poisoning you and your family? You would…