Fanconi anemia

Premature birth oximeter

Last Updated December 20th, 2021

What is Fanconi anemia ?

Fanconi anemia is a serious blood disorder that is characterized by the inability of the bone marrow to make enough new blood cells.  More than 50% of the people diagnosed with this disease get it before the age of 10. This disease is more common in people who have birth defects such as brachydactyly, skin pigmentation defects, microcephaly, microphthalmia and abnormal kidney structures.

This condition often results in the progressive deficiency of red blood cells, white blood cells, and platelets. People with this condition are also at an increased risk of developing bone marrow cancer. Fanconi anemia is equally prevalent in both men and women and in all ethnic groups.

Causes

MYELODYSPLASTIC SYNDROMES bloodFanconi anemia is a genetic disorder that is inherited. If there are mutations in at least 18 genes, the occurrence of this condition is high. The chromosomes of people affected by this condition are not able to repair the damaged DNA. Hence they break and rearrange easily leading to chromosome instability.

The majority of the Fanconi anemia cases happen due to mutations in one of these genes, FANCA, FANCC, and FANCG. These genes are responsible for providing instructions for the production of blood cells. Sometimes, the mutation of these genes may also lead to uncontrolled cell growth, which results in cancer.

Autosomal Recessive

This condition is mostly inherited in an autosomal recessive manner. If a person only has one abnormal gene of Fanconi anemia, he/she becomes a carrier, with no apparent symptoms. However, if a person gets 2 abnormal genes, one from each parent, then he/she gets affected by this condition.

If both the parents have the mutated gene related to this condition, the risk of it being passed on to their child (both male and female) is 25%. The risk of the child becoming a carrier is 50%. Lastly, the chance of the child not getting the disorder at all is 25%.  If the parents are consanguineous (close relatives), there is a higher chance of their child having and a recessive genetic disorder like Fanconi anemia.

This disorder can also be inherited if there are mutations in the following genes, BRCA2, BRIP1, FANCB, FANCD2, FANCE, FANCF, FANCI, ERCC4, FANCL, FANCM, PALB2, RAD51C, SLX4, and UBE2T.

The mutation of the FANCB gene mostly affects males as it is located in the X chromosome. Females with X-linked recessive trait are usually carriers as they have two X chromosomes. Males have only 1 one X chromosome that is inherited from the mother (fathers pass on the Y genes to males). If the male receives the X chromosome with the altered gene, he will develop this disorder.

Female and male carriers of the disease

Genetic Disorder_sickle cellFemale carriers of an X-linked disorder have a 25% chance (with each pregnancy) of producing a carrier daughter, 25% chance of producing a non-carrier daughter, 25% chance of producing a son who will be affected by the disease and 25% chance of producing an unaffected son.

Meanwhile, if a male with an X-linked disorder reproduces, he will pass on the abnormal gene to all his daughters. He will not be able to pass on the disorder to his son as males only pass on the X chromosome to their daughters.

Lastly, this condition can also be inherited in an autosomal dominant manner. This happens when there are mutations in the RAD51 gene. In dominant genetic disorders, only a single abnormal gene is necessary to cause a particular disease. The abnormal gene can be inherited from either parent or result from a new mutation in the patient. The risk of passing the mutated gene from parent to offspring is 50% in both males and females. People who develop FA due to a mutated RAD51 gene usually have a mutation that occurs in the egg or the sperm. In this instance, FA is not inherited from the parents.

Symptoms

The symptoms of Fanconi anemia are different from person to person. However, it is often characterized by a variety of physical abnormalities, which reveal themselves in early childhood. Some of the symptoms of Fanconi anemia are

  • Low birth weight
  • Gastrointestinal difficulties
  • Skin pigmentation
  • Small reproductive organs in males
  • Short stature
  • Kidney structural problems
  • Thumb and arm anomalies
  • Defects in tissues separating chambers of the heart
  • Small head
  • Small, crossed, or widely spaced eyes

Blood problems start once the individual reaches 6-8 years and they may start experiencing

  • Anemia
  • Tiredness
  • Sleepiness
  • Weakness
  • Lightheadedness
  • Dizziness
  • Irritability
  • Headaches
  • Pale skin color
  • Difficulty breathing
  • Cardiac symptoms

The more serious symptoms of this disorder are bone marrow failure and an increased risk of developing cancer.

Bone Marrow Failure

Bone marrow is a semi-solid tissue that is found inside the spongy portions of long bones. The main function of the bone marrow is to produce hematopoietic stem cells that eventually become platelets, erythrocytes (red blood cells) and leukocytes (white blood cells).

Progressive bone marrow failure usually happens before the age of 10. It is characterized by low platelet levels or low white blood cells.

Cancer

People who have Fanconi anemia are at an increased risk of developing certain cancers (acute myeloid leukemia and specific solid tumors)as compared to the general population. Fanconi anemia mainly causes cancer that affects the head and neck region, gastrointestinal tract, esophagus or gynecologic regions.

Who should be tested?

Premature birth oximeterAny infant born with the thumb and arm abnormalities should be tested for FA. Any person who develops aplastic anemia (a conditionwhich results in your body not producing enough new blood cells) at any age should also be tested for FA. People (especially those without a history of tobacco or alcohol use), who develop squamous cell carcinoma of the head neck, gastrointestinal or gynecologic system should also be tested. This is because chemotherapy and radiation may have an adverse effect on FA patients.

Diagnosis

This condition is usually diagnosed by a combination of methods that may include

Clinical evaluation

Although Fanconi anemia patients can be identified with certain physical abnormalities such as small head, deformed thumb, skin pigmentation, the doctors may order the following test to be certain

  • Ultrasonography of the kidneys and urinary tract
  • Hearing test
  • Developmental assessment (especially for toddlers and school-age children)
  • Evaluation by a hematologist
  • Full blood typing
  • HLA typing of the affected individual, siblings, and parents for consideration of hematopoietic stem cell transplantation
  • Blood chemistries
  • Bone marrow aspiration

Specialized tests

Chromosome breakage test

The widely used test for diagnosing FA is called a chromosome breakage test, which involves treating some of the patient’s blood cells in a test tube with a chemical that crosslinks DNA. DEB (diepoxybutane) and MMC (mitomycin C) are the two chemicals that are commonly used for this test. When the cells come in contact with these chemicals, the DNA breaks up. Normal cells are able to correct most of the damage but cells affected with FA display chromosome breakage. These tests can also be performed prenatally by obtaining cells from the amniotic fluid or the chorionic villi.

Molecular genetic testing

Molecular genetic testing can be done for all 18 genes that are related to FA. Firstly, a complementation test is done to identify why the gene is mutated. Once identified, sequence analysis of the gene is done to determine the specific mutation in that particular gene. If the mutation is not identified, deletion/duplication analysis has to be done for the genes associated with FA.

Treatment

The treatment of FA is done depending on the symptoms of the condition in each patient. Treatment plans usually require coordinated efforts by pediatricians, surgeons, cardiologists, kidney specialists (nephrologists), urologists, gastroenterologists, etc. These are some of the most common treatment methods for FA patients

Androgen administration

The administration of androgens (male hormones) is known to improve the blood count in approximately half of the patients diagnosed with FA. The first signs of this treatment plan will see the increase in hemoglobin, generally after a couple of months following treatment. The red blood cells count also improves. However, it takes time for the white blood cells and platelet count to improve. Also, the body builds resistance to this treatment after a while.

Hematopoietic growth factors

This therapy involves the administration of glycoprotein, a compound that stimulates the bone marrow to produce more granulocytes and stem cells. This improves the white blood cells (mainly neutrophil) count in some individuals. This therapy’s main side effect is that the patient may develop a skin condition called Sweet’s syndrome.

Hematopoietic stem cell transplantation

This therapy involves the transplantation of donor stem cells (preferably from a close relative) obtained from bone marrow, peripheral blood, or cord blood. The stem cells automatically increase the blood count in patients. HSCT remains the only curative treatment for patients with Fanconi anemia.

Surgery

Surgery is sometimes needed to correct the skeletal malformations associated with this disease.

Prevention

This condition cannot be prevented but people with a family history of this disease can undergo genetic counseling before planning to have a baby to understand the risks better. Pregnant women, who have a family history of this disease, should also do a genetic test to determine whether the baby has FA. This can be done via two procedures

Amniocentesis: In this procedure, the doctor uses a needle to remove some amniotic fluid, which is then tested for FA genes.

Chorionic villus sampling: This is done by inserting a tube through the vagina to take tissue samples of the placenta. The samples are then tested for FA genes.

If the baby is tested positive, the doctor will run more tests to determine the severity of the disease. If the disease is too severe, the couple may opt to undergo an abortion.

 

Dos and Don'ts

Dos
  • You should be careful not to injure yourself
  • You should get your blood count tests done regularly
  • You should undergo a genetic counseling session if you are planning to have a baby
Don'ts
  • Drink or smoke cigarettes. Nicotine and alcohol may increase the risk of chromosomal breakage in individuals with FA.
  • Feel low if you have FA. Improvements in blood and bone marrow stem cell transplants have greatly involved the survival rates of people living with this condition.
  • Play contact sports as you may get injured. People with FA should not risk injury as their blood might not clot due to low platelet count.

 

 

 

Related Conditions

Trending Topics

rubella IgG test
Rubella IgG Test The rubella IgG test is a blood test that checks for the rubella virus IgG antibodies present in…
random blood sugar test
Random Blood Sugar Test The random blood sugar or RBS test is prescribed mainly to check the level of sugar or glucose…
The real reason why you shouldn’t be eating ramen noodles Instant ramen noodles might be your go-to snack for your hunger pangs. But with each spoonful you are…
lipid-profile
Lipid Profile Lipid profile is a blood test that provides complete information on how much cholesterol is present in the…
Congestive Heart Failure ekg
EKG – Electrocardiogram An electrocardiogram, abbreviated as an ECG or an EKG, measures the electrical activity in the heart and used…
thyroglobulin test
Thyroglobulin (TG) Test Thyroglobulin test helps in measuring and monitoring the concentration of thyroglobulin. This test can be used as a…
anti-thyroglobulin antibody
Anti-Thyroglobulin Antibody test Anti-thyrogloubin antibody test measures the level of antibodies that attack the thyroid gland cells and are hence indicative…
diabetes symptoms in women
FBS Test – Fasting Blood Sugar FBS or fasting blood sugar test is a blood test that is used to determine the level of…
Ferritin blood test
Ferritin Test Ferritin test is a blood test that provides vital information on the level of RBCs and iron in…
RHEUMATOID_FACTOR_(RF)
Rheumatoid Factor (RF) Rheumatoid factor or RF is a blood test used to diagnose painful joint conditions such as rheumatoid arthritis…
Lectin: The common link of proteins between peas and people Lectins are a type of protein that are found majorly in legumes. Most people are find it easy…
TPAB test
Treponema Pallidum Antibody(TPAB) test Treponema pallidum bacteria a gram-negative bacteria that has helically coiled, corkscrew-shaped cells, responsible for STDs such as syphilis.
serum electrolyte test
Serum Electrolyte If there is an electrolyte imbalance in the body, a serum electrolyte test will help to find out…
Eustachian Tube : Functions and top home remedies to prevent its infection Pressure equalization, mucus drainage and protecting the middle ear from bacteria and viruses are the three important functions…
HELICOBACTER_PYLORI---IgG
Helicobacter Pylori – IgG Test Helicobacter pylori IgG test is a blood, saliva, and urine test performed to determine if the patien is…
cardiolipin antibody igm
Cardiolipin Antibody (ACL) –IgM Test This particular test measures the level of IgM type antibodies in the blood by using the ELISHA test…
serum zinc test
Serum Zinc Test The serum zinc test is a blood test performed to assess the zinc level in the blood (serum)…
EMA antibodies
Endomysial Antibodies (EMA) Test EMA test is an investigative blood examination to locate the presence of certain antibodies, called Endomysial antibodies or…
dengue-test
Dengue NS1 test Dengue NS1 is a blood test used to determine the onset of dengue fever. Dengue fever is transmitted…
Atkins diet weight loss
Atkins Diet: The right steps to carb control that can help you lose those pounds fast The Atkins diet is a high fat, low-carb diet with proven weight loss benefits that is flexible enough…
hsv igg test
Herpes Simplex Virus I (HSV)-IgG Test Herpes Simplex Virus I (HSV)-IgG is used to detect the presence of the herpes virus so that the…
passion fruit juice
Passion fruit: How one exotic fruit can help you fight infections and cancer! Passion fruit: Why does this exotic fruit have such an enticing name? And how can it protect you…
Pulmonary Function Tests Pulmonary function tests (PFT’s) are non-invasive breathing tests employed for diagnosing and monitoring lung diseases such as bronchitis
IGE test
IgE test – Immunoglobulin E IgE or immunoglobulin E test is a test that measures the level of IgE in the blood and…
TBHQ: A carcinogen lingering in your child’s favorite snacks TBHQ - Why you should shun the practice of eating instant noodles or microwave popcorn to get rid…
bilirubin-test-result
Bilirubin Test Bilirubin is a substance produced in the body as a result of red blood cell breakdown. A bilirubin…
beta 2 glycoprotein 1 IgG
Beta 2 Glycoprotein 1 IgG Beta 2 glycoprotein 1 antibody test involves detecting and measuring the presence of the IgG class of beta…
Free T3 test
Free Triiodothyronine (FT3) Test The free triiodothyronine or FT3 test is an important blood test that is used to detect the level…
erythropoetin test
Erythropoietin (EPO) Test Erythropoietin stimulates the production of RBCs in bone marrow. An erythropoietin test is done to diagnose blood disorders…
abdominal-CT-scan- image
Abdominal CT scan Abdominal CT scan is a diagnostic imaging technique that provides a clear picture of the state of internal…
carrageenan seaweed
Carrageenan: How a simple seaweed extract could better your gut health & immunity Eat more ice cream to prevent cold and flu? –With carrageenan you get one simple seaweed extract that…
11 unbelievable health benefits of thyme you didn’t know! Thyme is a herb that has been used in alternative medicine.It is a well known seasoning in the…
EEG
Electroencephalogram – EEG EEG or electroencephalogram is a diagnostic tool used to access the functioning of neurons and brain activity to…
lifestyle diseases
The Big 5 lifestyle diseases: How your everyday living might be killing you You'd be shocked to know how unhealthy and potentially fatal your everyday routine could be. Has the modern…
Panera bread steak arugula
Panera Bread: The truth behind this “healthy” restaurant chain What to order and what to avoid when dining at Panera Bread ? Know more about this popular…
Piaget stages: Do they accurately describe the way the human brain develops?  A common assumption was that children are less competent thinkers as compared to adults, but this was refuted…
hepatitis B envelope antigen
Hepatitis B Envelope Antigen (HBeAg) The HBeAg or hepatitis B envelope antigen test is a screening test used to diagnose the onset of…
Squid-ink-spaghetti
Squid Ink: A unique food coloring and flavoring agent Want to add a unique black color to your pasta, noodles and ice-creams? How can you use squid…
Squid-ink-spaghetti
Squid Ink: A unique food coloring and flavoring agent Want to add a unique black color to your pasta, noodles and ice-creams? How can you use squid…
Squid-ink-spaghetti
Squid Ink: A unique food coloring and flavoring agent Want to add a unique black color to your pasta, noodles and ice-creams? How can you use squid…
eating disorder anorexia
Eating Disorders: Lifestyle choice or a psychological condition? Is eating disorder just a harmless bad habit? Or does it represent grim psychological disorders? Do you want…
free psa test
Free PSA Test The free PSA test is used to detect the level or percentage of free PSA in the body…
POSTPRANDIAL-BLOOD-SUGAR
Post-Prandial Blood Sugar Postprandial blood sugar test is an important diabetes diagnosing tool. This simple blood test measure the level of…
hidden causes obesity
8 hidden causes of obesity you probably didn’t know! Did you know that around 2 billion people worldwide are either overweight or obese? Are you too a…
Maltitol: Things you must know about this artificial sweetener Sugar alcohols are produced by fruits and vegetables. Maltitol is an artificially produced sugar alcohol and is used…
Hydroquinone: Is it the best topical treatment for hyperpigmentation? Darkening of the skin due to high melanin levels is called hyperpigmentation.  Hydroquinone interferes with melanin production thus treating…
Tachycardia heart
Cardiac Profile Cardiac profile is panel of blood tests performed to check cholesterol level and other heart disease markers to…
lipoprotein A
Lipoprotein (A) Test Lipoprotein (A) test is used to measure and monitor the levels of LDL(Low-Density Lipoprotein) in the bloodstream in…
sugar toxic health
Sugar: 7 new shocking truths revealed about the sweet poison Can drinking soda bring you closer to death? Is sugar slowly poisoning you and your family? You would…
hlab27 test
HLA-B27 test The HLA-B27 is a blood test that is used to determine the level of a particular protein called…
How do neutrophils protect you from fatal bacterial attacks? During an infection, certain enzymes alert the mature neutrophils.  Neutrophils then travel through the bloodstream to the affected…
Milk Thistle skin
Milk Thistle: Find possible cures for fatal diseases in these purple blooms Milk thistle is well-known for treating liver conditions. However, did you know that it comes with a plethora…
CT-scan-machine
CT – Computed Tomography Scan CT scan or computed tomography scan is an diagnostic imaging technique where cross-sectional images of body are obtained…
Anti-CCP Test – Anti-Cyclic Citrullinated Peptide Anti-ccp or ACCP test is a blood test that is primarily employed to diagnose the onset of rheumatoid…
Surgery or home-remedy; what is the right way to treat a burn The treatment of a burn injury depends on its severity. You can save a life by offering the…
Silicon Dioxide: How can a component of sand be essential to your wellbeing? Silicon is one of the most abundant elements in the nature. Find out how silicon dioxide can prove…
smelling-salts-benefits
The actual science behind smelling salts and how it helps in injury recovery Most smelling salts are a mixture of ammonium carbonate and some perfumes which are sniffed by an individual…
BRAT Diet: What is the right way to follow this diarrhea-relieving diet? BRAT diet, a simple diet consisting of just bananas, rice, applesauce, and toast, can help you combat the…
blood ketone test
Blood Ketone (D3HB) Test The Blood Ketone Test measures and monitors the levels of ketone in the blood which is usually performed…
copper serum test
Copper Serum Test Copper serum test checks for abnormal levels of copper in the body. Both high and low levels of…
C-Reactive Protein Test A CRP or c-reactive protein blood test is an important diagnostic tool used to determine the risk of…
Cystoscopy Cystoscopy is intended to look at the abnormalities in the ureters, bladder, and urethra, to assist surgeries performed…
AUTOIMMUNE HEPATITIS liver
Hepatitis Profile A hepatitis profile or a hepatitis panel is a blood test that checks for markers of hepatitis infection…
beautiful smiling woman enjoying high fiber energy bar with roughage
The importance of roughage in diet Eat these high fiber foods to increase your dietary roughage. Quick tips to boost daily roughage consumption. Check…
rosacea-treatment--before-_-after
The best and safest ways to treat rosacea Rosacea is a skin disease that is characterized by reddish hives and rashes on the face. Read more…
beta 2 glycoprotein 1 igm
Beta 2 Glycoprotein 1 IgM The Beta 2 glycoprotein 1 IgM test detects IgM class of antibodies in the blood.The presence of beta-2…
GM Diet: The fastest way to lose weight or yet another hoax diet? General Motors started this trend of extreme dieting for 7 straight days to ensure its employees were able…
autoimmune diseases facts
Autoimmune Diseases: Find out if your body is attacking you right now Did you know your body can harm itself? What are autoimmune diseases and why does it harm some…
urinary microalbumin test
Urinary Microalbumin Test The urine microalbumin test is a urine test that measures the level of microalbumin or protein in the…
DHEA wrinkles
DHEA: Now get unbelievable age defiance with this wonder hormone! DHEA is known popularly as the age-defying hormone. This supplement is widely used to slow down aging and…
CBC blood test
CBC (Hemogram 6-part diff) blood test CBC (Hemogram 6-part diff) blood test refers to the test that measures the number of RBCs, WBCs, etc…
Top 6 remedies to treat a razor burn at home Symptoms of razor burn include bumps on the skin, redness, and irritation of the skin. Find easy and…
immunoglobulin M
Immunoglobulin M Test Immunoglobulin M is the largest and the first produced antibody which helps in the prevention or fighting of…
Goji berry: A traditional Chinese berry that packs the best of antioxidants Goji berry is an ancient berry that is considered to be power-packed with nutrients and antioxidants. Which means…
How accurate is the hair follicle drug test? Hair follicle drug test is one of the best ways to identify drug use in professional circles. But…
Sputum test Sputum test is a commonly used diagnostic tool that is used to examine the presence of pathogens in…
low fodmap plan
Troubled with IBS? Here’s a complete roadmap to the low FODMAP diet Leaky & inflammatory gut troubling you? No medicine bringing you relief from the pain? Why not try the…
lp-pla2
LP-PLA2 Test The LP-PLA2 test is a test which is carried out to assess the levels of Lipoprotein-Associated Phospholipase A2…
thyroid_scan
Thyroid Scan Thyroid scan is a diagnostic procedure that aims to view the thyroid gland and detect any growths or…
How to correctly perform nasal irrigation using a Neti Pot? Neti pot has been a part of Ayurveda since centuries. This ancient tool is extremely effective in treating…
antinuclear antibody test
Antinuclear Antibody Test – (ANA) Antinuclear antibody or ANA test is a blood test that measures the level of ANA antibodies that are…
Green, brown, & bitter: The instant advantages of including fenugreek in your diet Did you know the earliest usage of fenugreek can be traced back to the Egyptian civilization? Find out…
chloride test
Chloride Test A chloride test of the blood checks the level of chloride in body, an important factor governing the…
Juice Plus: Can you really replace actual fruits with pills?  Juice Plus supplements intend to fill nutritional gaps present in our daily diet. But how successful have they…
kshar sutra
Kshar sutra treatment for piles, fissures and fistula Read to know the benefits and side effects of kshar sutra to treat anal piles, fissures, and fistula…
Jackfruit: Slice your way into higher immunity, better digestion, & more… Native to the South East Asia, the jackfruit is a fruit brimming with thousands of health benefits. Discover…
CLA: A breakthrough weight loss supplement with minimal side effects Tried every weight loss supplement in the market with no substantial gain? Why not try CLA supplements, derived…
17 OH Progesterone test The 17 OH progesterone test is a simple blood test that is mainly used to diagnose the cause…
Chest X-Ray A chest x-ray is a diagnostic test that uses x-rays to visualize the structures inside your chest. It…
ANTI-MICROSOMAL-ANTIBODY-(AMA)
Anti-Microsomal Antibody AMA Test AMA or anti-microsomal antibody test is a blood test that measures the activity of AMA in the body…
sodium blood test
Blood Sodium Test A blood sodium test measures the amount of sodium (an important electrolyte) in your body. It is also…
dance health benefits
5 unbelievable effects of dance on your overall health! You enjoy dancing, but did you know what else it does to your body? Dancing is not only…
Love tea, hate tannins? Rooibos tea is just what you need The market is brimming with a multitude of herbal teas. But what makes rooibos tea (or red bush)…
Trisodium Phosphate: How a paint thinner made its way into your breakfast Ever thought how toxic chemicals find their way into our foods? How can they harm our body? And…
ASTtest-liver
AST- Aspartate Aminotransferase Test AST test is a blood test that is used to measure the level of a particular liver enzyme…
occupational hazards types
Occupational Hazards: How to vouch for your health at your workplace Occupational hazards affect millions worldwide. Chemical spills, faulty wires, deadly pathogen, and work-stress can happen anytime. Follow these…
DHEAS test
DHEA Sulfate (DHEAS) Test DHEAS or DHEA Sulfate test is prescribed if an individual shows symptoms of abnormal adrenal actvity such as…
Jack in the box fast food
Jack In the Box : The perils of surging fast food culture in the USA Jack in the Box - How a culture of fast-food can clog your arteries, weaken your heart, fatten…
Jicama: A fiber-rich tuber for your weight loss goals Pronouced as HEE-kah-ma, Jicama is the "new kid on the block" that has taken the world by the…
Helicobacter pylori IGA
Helicobacter Pylori – IgA Test The H.pylori IgA test is a blood test used to identify the level of IgA antigen in the…
biotin for hair
Biotin: One-stop-shop for shiny hair and an active body! What is common to bananas, eggs, sweet potatoes, and liver? These are delicious and rich in biotin ;…
myelogram
Myelography Myelography is an important diagnostic tool that is used to investigate and identify abnormalities in the spine and…
glucose-tolerance
Oral Glucose Tolerance Test – GTT Glucose tolerance test (or Oral GTT) is used to detect the onset of diabetes or prediabetes conditions. It…
iron deficiency profile
Iron Deficiency Profile An iron deficiency profile is a battery of blood tests which are performed in order to determine the…
tonometry
Tonometry Tonometry uses a device called tonometer to measure the pressure inside the eye. This pressure is depends upon…
waterchestnut
Water Chestnuts: The tastiest ways to include this healthy tuber in your diet Water chestnut is not a nut after all. It is a tuber (much like the potatoes) growing close…
Rubella IgM test
Rubella IgM Test The Rubella IgM test is a blood test that is performed to diagnose the presence of the rubella…
arterial-blood-gas
Arterial Blood Gas Analysis Arterial blood gas analysis is a diagnostic procedure used to determine the volume of oxygen and carbon dioxide…
xylitol gum
Xylitol : Is this the right sugar substitute for you? Discovered during World War 2 owing to sugar shortage, xylitol has become a common name in pharamaceutical industry.…
Hysteroscopy_procedure
Hysteroscopy Hysteroscopy is a minimally invasive tool to help specialists view the uterus to diagnose and even treat several…
Poop chart: Top things you didn’t you your poop could reveal about you Bristol poop chart was designed during the 1990s in order to help doctors identify various types of poops…
Inversion Therapy: The anti-gravity way of healing chronic back pain Inversion therapy involves suspending a person upside dow using different types of equipment. This works by taking the…
Stye : The best natural home remedies to ease the pain Styes developing inside the eyelid tend to be more painful whereas external styes are less painful and ooze…
sodium chloride
Halotherapy: How inhaling salt can work wonders for your body Halotherapy is quickly gaining popularity amongst those with respiratory diseases. It has shown promise in its treatment.
kidney stones
Kidney stones Kidney stones are solid substances made up of crystals. They can be of various sizes. Treatment depend on…
Ovarian cyst diagnosis and treatment
Ovarian cysts Know everything about ovarian cysts, its causes, types, diagnosis and treatment options such as home remedies and surgical…
Ovarian cyst diagnosis and treatment
Ovarian cysts Know everything about ovarian cysts, its causes, types, diagnosis and treatment options such as home remedies and surgical…
shiitake mushrooms healthy
What are Shiitake Mushrooms and why should you eat them? Shiitake Mushrooms are well known for their smoky and robust taste. However, did you know they are replete…
dhea adrenal
Androstenedione Test Androstenedione is produced by the adrenal gland, the test of the levels of Androstenedione helps in the evaluation…
The science behind daith piercing: Can it really cure migraine? Since the ear has several pressure points, it is believed that daith piercing activates the vagus nerve and…
vital organ diseases
Common diseases that could cripple your vital organs Brain, heart, kidney, lungs, and liver - these vital organs are indeed vital for your survival. However, these…
Balneotherapy jacuzzi
5 things you didn’t know about balneotherapy and how you can do it at home Sauna baths have been popular since a long time. But how much more beneficial can balneotherapy be as…
Threatened abortion
A few facts about threatened abortion A threatened miscarriage indicates an early pregnancy loss. Look out for symptoms like bleeding, vaginal discharge, and pain.
Coconut sugar: What is it and is it healthier than table sugar? In the long list of things that the wonderful coconut gives us, coconut sugar is another remarkable addition.…
woman with abdominal pain holding ovulation calendar
Ovulation – facts to know about ovulation Learn how and when ovulation occurs, demystify common misconceptions, identify symptoms, methods of detection and right period for…
improve digestion weight loss
Power up your gut: 8 proven steps on how to improve your digestion Did you know you have a colony of bacteria in your gut that help you in digesting food?…
hidden benefits walking
9 benefits of walking we bet you didn’t know! Did you know walking can be the miracle pill for eternal youth? Everyone knows walking is good for…
Optavia diet
The features of an Optavia diet The Optavia diet endorses pre-packaged meals and snacks called "fuelings" that are tasty, low in calorie, and incorporates…
L-theanine attention
L-Theanine: Better sleep, higher focus, and many other benefits Did you know that L-theanine found in green tea can make you sleep better and be focused at…
Bloodtestalbumin
Albumin Test Albumin test or blood serum test is a liver function test that measures the amount of the protein…
These are the top foods to increase your hemoglobin count It is important to add iron-rich foods into your diet in order to increase hemoglobin. Deficiency of hemoglobin could…
blood elements analysis
Vitamin Profile Your doctor will recommend you undergo the vitamin profile test if you are showing signs of either vitamin…
Hemp Seeds: The actual science behind this controversial crop Inspite of being credited as a superfood, hemp seeds are still shrouded with layers of controversies. Are these…
dandelion weight loss
Caralluma Fimbriata: How to eat this cactus to lose weight Caralluma fimbriata is a miracle cactus that can be safely consumed by most for losing weight and boosting…
Experts reveal the safest ways to perform an enema at home The idea of pushing some up your rectal area might make you queasy but an enema could actually…
maltodextrin sugar
Maltodextrin: What are the hidden health benefits of this food additive? Maltodextrin is one of the few food additives that has been relatively deemed safe. Many experts now have…
anti ds dna test
Anti Ds-DNA antibody Test The  Anti Ds-DNA antibody test is used to diagnose the disease called lupus or more aptly the SLE(Systematic…
Is bronchitis contagious? And how to prevent this infection? It is acute bronchitis that is contagious which means you can contract it from another person or you…
Vitamin K2: 8 reasons why you need this bone-building & cancer-fighting nutrient Vitamin K2 is claimed to be essential for your bone health, for reducing the risk of cancer, and…
Kava: Is it the healthy substitute for alcohol you have been waiting for? Native to the beautiful South Pacific islands, Kava is a famous beverage rooted in the local culture. It…
Crossfit with rope
CrossFit: Now get the perfectly sculpted body with this explosive gym routine CrossFit is a fitness regimen that makes use of high-intensity exercises in a shorter period to achieve muscle…
free thyroxine ft4
Free thyroxine test (FT4) The FT4 or free thyroxine test is used to detect the level of free thyroxine of FT4 thyroid…
leptospira Igm test
Leptospira-IgM Test A Leptospira-IgM test is a blood test which is carried out to detect anti-Leptospira IgM antibody. Leptospirosis is…
cytomegalovirus iGG
Cytomegalovirus (CMV)- IgG Test The cytomegalovirus IgG is the immunoglobulin protein produced by our immune system when the body is infected by…
Hepatitis A virus infected liver
Hepatitis A Virus (HAV) Total Blood test to look for IgM antibodies to know if you are infected with Hepatitis A virus (HAV),…
low carb diet meal
Low carb diet : Go high on fats and low on carbs for a leaner body! Did you know that sugar is the new fat? Going low on carbs and high on fats &…
PROLACTIN-(PRL)
Prolactin Test (PRL) Prolactin or PRL is a lactogenic hormone produced to induce milk production in lactating mothers. PRL test measures…
How can berberine supplements help you live longer and healthier? Berberine is a turmeric look-alike herbal extract that is credited with numerous health benefits ranging from diabetes cure…
sleep deprivation
Don’t let your sleep deficit grow into memory loss or heart attack Why is sleep important for us? How could sleep deprivation harm you? We bet you didn't know about…
Exercises or diet? Find out the healthiest way to gain weight Tired of being called skinny all the time? Looking for healthy ways to beef up? Why not try…
Bubble Tea: Bubbling with nutrition or a hidden sugar mine? The tapioca pearls present in the tea looks like bubbles and hence the name bubble tea became popular.…
Okra: How can this nutrient-dense vegetable help you fight diabetes? Okra is a food which is rich in nutrients and minerals which are extremely essential for a healthy…
black seed oil benefits
Black Seed Oil: What secret benefits could it bestow on your health? Black seeds or nigella seeds are tiny packets of health brimming with amazing benefits. Find out why should…
Quinine: How gin and tonic came to be known as a potent health elixir The discovery of quinine-containing tree bark is sometimes considered the most serendipitous medical discovery of the 17th century.
Barium-enema
Barium Enema Barium enema is also known as colon x-ray. Here, the patient is asked to consume small amount of…
lipase test
Lipase Test A lipase test is a blood test performed to quantitatively measure the level of the enzyme lipase in…
Tissue Transglutaminase Antibody (tTG) Test Transglutaminase is an enzyme present in our body and is involved in protein metabolism. A tTg test is…
Ca 19.9 test
CA19.9 Test CA 19.9 is a cancer antigen that exists on the surface of cancer-causing cells. The levels of CA…
The Shepherd's diet
Facts about the Shepherd’s diet Kristina Wilds promoted Shepherd's diet, a Christian-based diet that highlights Jesus Christ's diet as mentioned in the Bible.
vdrl test syphilis
VDRL Test The VDRL test is a blood test that is used to diagnose sexually transmitted or venereal diseases, primarily…
antiHEV IgM test
Anti hepatitis E virus (Anti HEV) IgM Test Anti HEV IgM test determines the level of the IgM antibodies in the blood, The disease is often…
carbamazepine
Carbamazepine / Tegretol test The carbamazepine is a drug that is used to treat epilepsy and the carbamazepine test is performed to…
diverticulitis diet
Diverticulitis diet: The right way to eat if you suffer from the disease Are you suffering from diverticultis but clueless about your diet ? Read this complete plan for diverticulitis diet…
HSV-IgM test
Herpes Simplex Virus (HSV)-IgM Test The HSV-IgM class antibody is produced by the body a few days after an initial HSV infection and…
Astaxanthin: Why experts believe it could be 550x more potent than vitamin E! What is astaxanthin and why is this new supplement on the block touted as the most powerful antioxidant…
diabetic foot ulcer remedy
Diabetic foot ulcer Read to know everything about diabetic foot ulcer,causes,symptoms,diagnosis,treatment prevention and outcome for patients
Hymenoplasty
Hymenoplasty Read on to find out all about hymenoplasty, the procedure, post-surgery care, the risks, and the benefits.

Related Conditions

Want to live a healthy lifestyle?

Subscribe to free FactDr newsletters.

REVAMP YOUR

LIFE

HEALTH

WELLNESS

If you're enjoying our website, we promise you'll absolutely love our new posts. Be the first one to get a copy!

Get factually correct, actionable tips delivered straight to your inbox once a week.

I want the latest scoop on :

We hate spam too. We will never share your email address with anyone. If you change your mind later, you can unsubscribe with just one click

By clicking Subscribe, I agree to the FactDr Terms & Conditions & Privacy Policy and understand that I may opt out of FactDr subscriptions at any time.

Worried about your health?
Don't worry. Just consult a doctor now to get quick answers to your questions.

Consult a doctor now