Diabetes

Diabetes foot

Last Updated December 20th, 2021

Overview of diabetes

Old age is associated with numerous pathological complications and diseases that disrupt the normal functioning of the body. Most of these diseases are apparently chronic and can be regulated through expert medications and diet recommendations. In recent years, Diabetes has been identified as the primary cause of digestive complications within the body. It not only affects an individual’s overall health but also poses a socio-economic threat. The prevalence of diabetic disorders can be traced back to 2004 when more than 220 million people worldwide were reported with Diabetes. WHO has also projected the doubling of diabetes rates between 2005 to 2030. Global standards of healthcare must be raised to address the impending issues related to Diabetic conditions.

What is Diabetes?

Diabetes blood testDiabetes refers to a group of pathological conditions in which the concentration of blood glucose increases due to shortage of insulin within the body due to pancreatic dysfunctions. In this condition, the body cannot convert glucose from food into energy, leading to excess accumulation of unused glucose within the body. According to recent findings by WHO, death due to diabetic diseases occurs mostly under the age of 70. Although Diabetes is usually a disease of old age, children in their growing years have also been diagnosed with diabetes in some cases.

What are the main causes of Diabetes?

Diabetes is more prominent in low and middle income countries and might arise due to multiple factors. The primary cause of Diabetes is the scarcity of insulin within the body that absorbs blood glucose and utilizes it to produce energy. This occurs under two circumstances:

  • The pancreas cannot produce enough insulin to control blood glucose level
  • The insulin produced cannot be efficiently utilized to regulate blood glucose

Both these conditions are attributed to functional abnormalities of the pancreas.

What are the causes of Type 1 Diabetes?

These causes mainly belong to the category of genetic factors or past infections:

  • Auto-immune destruction of beta cells of pancreas (responsible for storage and release of insulin)
  • Presence of antibodies to islet cells (responsible for insulin production) in the blood
  • Gradual decline in the secretion of insulin

What are the causes of Type 2 Diabetes?

Diabetes sugarThese causes are mainly related to factors such as :

  • Obesity
  • Age (increased insulin resistance)
  • Insufficient physical activities
  • Heredity
  • Ethnicity (African Americans, Native Americans, Hispanics)
  • Polycystic Ovary conditions

The above factors combine to give rise to the following conditions :

  • Insulin resistance in the liver and skeletal muscles occurs, causing increased glucose production from the liver.
  • Excessive generation of free fatty acids by fat cells leading to insulin deficiency
  • Beta cell damage causes reduced insulin production

What are the main warning signs and symptoms?

The symptoms of diabetes vary according to the type of Diabetes. The generalized symptoms are stated below:

  • Excessive thirst and urination
  • Extreme fatigue and headache
  • Delayed recovery from injuries
  • Abnormal weight loss/gain
  • Pain in limbs
  • Unclear vision
  • Itchy and reddish skin (at times with rashes)
  • Abnormal loss/increase of appetite
  • Irritability and frequent mood swings

What are the different types of diabetic diseases?

Two major categories are Diabetes has been studied so far, that cause 80% of death in low and middle-income countries. These are – Diabetes Mellitus and Diabetes Insipidus. These are discussed below:

Diabetes Mellitus (DM): It refers to a group of metabolic conditions that lead to hyperglycemia (abnormal increase in blood glucose level). This condition is caused by insufficient production or utilization of insulin. It can be further classified into two types: (a) Type 1 Diabetes and (b) Type 2 Diabetes

  • Type 1: It occurs due to insufficient insulin production. It is also called Juvenile Onset Diabetes and contributes to 5-10 % of diabetes cases (according to CDC reports). In this case, the pancreas cannot generate sufficient insulin needed to control blood glucose level due to destruction of beta cells. Patients belonging to this category undergo artificial intake of insulin to make up for insulin deficiency in the body.
  • Type 2: It is also called Adult-onset Diabetes and occurs due toan insufficient utilization of insulin. WHO reports claim that Type 2 Diabetes affects more than 90% of Diabetic patients worldwide. The primary risk factors of this type of Diabetes are excessive body weight, and limited physical activities.

Diabetes Insipidus (DI): It is characterized by excessive thirst and production of large volumes of urine. In extreme cases, it might result in frequent bedwetting or dehydration. Children suffering from Diabetes Insipidus exhibit symptoms nausea, irritability, disturbed sleep and diarrhoea. Diabetes Insipidus has the following subtypes-

  • Central DI: It is caused due to damage of pituitary gland (due to head injuries, genetic disorders or neurosurgery) resulting in disturbed storage and release of ADH (Antidiuretic hormone).
  • Nephrogenic DI: This disease is caused due to the impaired response of the kidney to ADH due to certain medications or chronic diseases (Polycystic Kidney).
  • Dipsogenic DI: This type of diabetic disease occurs due to the damage of the thirst center located at the hypothalamus. It causes excessive thirst and urination, leading to sodium imbalance in body fluids.
  • Gestational DI: Gestational diabetic condition is observed in 2-5 % of women during the pre-natal stage, but it does not persist after the pregnancy period. It is caused due to the destruction of ADH in mother by an enzyme produced by the placenta.

Are there some long-term systemic complications?

Diabetic diseases in any form might leave long-lasting detrimental impacts on the patient’s body. The important ones are listed below-

  • Permanent renal failure
  • Cardio-vascular diseases
  • Foot ulcers
  • Diabetic retinopathy

Treatment & Prevention

Diabetes footThe treatment chiefly depends on the type of diabetes. However, certain measures such as intake of a healthy diet, maintaining a healthy weight, a regular physical activity can help in managing the condition well.

Type 1 – Regular blood sugar checks, calorie counting and use of insulin injections or pumps are required.

Type 2 – Diabetes medication and/or insulin are administered in this case. Regular monitoring and the evaluation of the blood sugar levels are required. Certain lifestyle changes can help in controlling the spike in the blood sugar levels.

  • Blood sugar level monitoring: Based on the treatment plan, the blood sugar level is usually checked 1 to 4 times in a day. The A1C levels are usually checked in order to evaluate the average blood sugar levels in the past 2 to 3 months. As compared to the regular blood sugar level tests, the A1C test is considered as better indicators of the effect of the diabetes management plan. An elevated A1C level indicates changes should be made in the oral medications, insulin dose, diet etc.
  • Insulin therapy: Insulin is essential for survival for individuals with type 1 diabetes. However, insulin administration may also be required in cases of type 2 diabetes or gestational diabetes.
  • Medications: Medications prescribed for diabetes have a different mechanism of action. They can help to stimulate the pancreas to produce more insulin; they can block the intestinal or stomach enzymes that metabolize carbohydrates or make tissues more sensitive to insulin. For instance, oral medication metformin is prescribed in cases of type 2 diabetes.

A pancreas transplant is performed in some cases as an alternative to insulin therapy. Transplants are not successful in all the cases and have grave risks involved. Bariatric surgery is an option considered for patients with type 2 diabetes having a body mass index (BMI) higher than 35. Gestational diabetes and prediabetes are managed by lifestyle changes and by keeping the blood sugar levels under check. In some cases, medications or insulin might be prescribed.

Management of weight, intake of appropriate diet, and regular physical activities are methods to reverse prediabetes and prevent the occurrence of type 2 diabetes.


TL;DR?

Facts

  • As per the American Diabetes Association, in general, the A1C levels below 7% are optimum in most of the cases of diabetes.
  • Insulin is not administered orally as its effect is hampered by the stomach enzymes.

Facts

  • You can delay the occurrence of type 2 diabetes by a moderate physical activity of least 150 minutes in a week and by losing 7 percent of your body weight.
  • The prevalence of diabetes in the year 2013 was found to be in around 382 million individuals.

Facts

  • It is estimated that 1.25 million individuals in the United States have type 1 diabetes and the newly diagnosed cases will be nearly 40,000 each year.

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Dos and Don'ts

Dos
  • Seek medical attention.Do not ignore symptoms such as blurred vision, fatigue, increased thirst, dry mouth etc. Maintain a healthy body weight so as to prevent the ill effects of obesity on health.
  • Maintain a healthy lifestyle. A healthy lifestyle and a balanced diet are essential for controlling blood sugar levels. The diet should be low on saturated fats and carbohydrates and high on fiber.
  • Follow an exercise routine. Regular physical activity is essential for keeping the blood pressure under control and maintaining a healthy body weight.
Don'ts
  • Involve in smoking. Smoking can augment the ill effects on the body that are caused as a result of diabetes.
  • Miss the dose of insulin. Consult your doctor in case you are planning to fast. Taking a regular dose of insulin when you fast, might cause hypoglycemia (low blood sugar levels), which is life-threatening.

 

 

 

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The features of an Optavia diet The Optavia diet endorses pre-packaged meals and snacks called "fuelings" that are tasty, low in calorie, and incorporates…
GM Diet: The fastest way to lose weight or yet another hoax diet? General Motors started this trend of extreme dieting for 7 straight days to ensure its employees were able…
Kava: Is it the healthy substitute for alcohol you have been waiting for? Native to the beautiful South Pacific islands, Kava is a famous beverage rooted in the local culture. It…
Love tea, hate tannins? Rooibos tea is just what you need The market is brimming with a multitude of herbal teas. But what makes rooibos tea (or red bush)…
How seitan proved to be a blessing in disguise for vegans worldwide Can only meat-eaters enjoy delicious juicy steaks and burgers? With seitan, the best meat substitute available today,even vegans…
How can berberine supplements help you live longer and healthier? Berberine is a turmeric look-alike herbal extract that is credited with numerous health benefits ranging from diabetes cure…
How accurate is the hair follicle drug test? Hair follicle drug test is one of the best ways to identify drug use in professional circles. But…
Bubble Tea: Bubbling with nutrition or a hidden sugar mine? The tapioca pearls present in the tea looks like bubbles and hence the name bubble tea became popular.…
Balneotherapy jacuzzi
5 things you didn’t know about balneotherapy and how you can do it at home Sauna baths have been popular since a long time. But how much more beneficial can balneotherapy be as…
CT-scan-machine
CT – Computed Tomography Scan CT scan or computed tomography scan is an diagnostic imaging technique where cross-sectional images of body are obtained…
blood elements analysis
Blood Element Analysis Test A blood element analysis is a blood test performed to measure the level of toxic elements such as…
antihepatitis core antigent
Anti-Hepatitis B Core Antigen (AHBc) Total Anti-hepatitis B core antigen (AHBC ) is a blood examination and the only serological marker of infectious blood…
antiHEV IgM test
Anti hepatitis E virus (Anti HEV) IgM Test Anti HEV IgM test determines the level of the IgM antibodies in the blood, The disease is often…
complement c4 test
Anemia Profile Anemia Profile test (Basic) is a blood screening test that measures the levels of important components of the…
Squid-ink-spaghetti
Squid Ink: A unique food coloring and flavoring agent Want to add a unique black color to your pasta, noodles and ice-creams? How can you use squid…
Squid-ink-spaghetti
Squid Ink: A unique food coloring and flavoring agent Want to add a unique black color to your pasta, noodles and ice-creams? How can you use squid…
Squid-ink-spaghetti
Squid Ink: A unique food coloring and flavoring agent Want to add a unique black color to your pasta, noodles and ice-creams? How can you use squid…
acne removal tips
Anatomy of acne: 7 instant steps to kiss those zits goodbye Blackheads, whiteheads, or pimples-call them what you may. Acne is never good news.Did you know some of the…
improve digestion weight loss
Power up your gut: 8 proven steps on how to improve your digestion Did you know you have a colony of bacteria in your gut that help you in digesting food?…
Horny Goat Weed: Can it improve libido in human beings too? This plant got its name as Horny Goat Weed when one of the goats feeding on the plant…
Rick Simpson’s Oil: The truths and controversies of this cannabis product Rick Simpson's Oil is an extract from the much-controversial plant, Cannabis. What is the actual truth behind the…
Erythritol: A healthy sugar substitute or yet another marketing ploy? Erythritol is a popular choice of a healthy alternative sweetening agent in foods. But how healthy can a…
Oxalates: How healthy greens can sometimes be bad news for your kidneys Oxalates are compounds present in a majority of healthy foods. However, at times an overconsumption of these could…
sodium blood test
Blood Sodium Test A blood sodium test measures the amount of sodium (an important electrolyte) in your body. It is also…
pilonidal sinus
Pilonidal sinus Pilonidal sinus is more common in young men than women. Learn about treatment options, surgical management, risks, and…
hidden benefits walking
9 benefits of walking we bet you didn’t know! Did you know walking can be the miracle pill for eternal youth? Everyone knows walking is good for…
aspartame or sugar
Aspartame – Hidden truths about this storm in a teacup Aspartame, the artificial sweetener, has gone under the scanner on several occasions for allegedly doing more harm than…
gallbladder diet tomato
Gallbladder surgery :Tips on post-operative care and diet What to eat post a gallbladder surgery? What are the key things to avoid if you had a…