Plague


Last Updated October 31st, 2019

What is the plague?

Plague, also referred to as the black plague, is a zoonotic disease that is caused by Yersinia pesti, a type of bacteria. This disease affects humans as well as other animals. Rodent fleas – which are found in rats

mice, squirrels, rabbits, prairie dogs, chipmunks, voles – are normally the vectors that transmit this disease from animals to humans. However, humans also contract this disease when handling an infected animal.

Plague is one of the oldest diseases known to man. During the middle ages in Europe, the plague was responsible for the deaths of millions of people. Today, plague can be treated effectively by antibiotics, although it can still be life-threatening in the absence of prompt treatment.  Many cases of plague are still prevalent in parts of Asia and Africa.

A brief history

The first recorded plague pandemic was known as the Justinian Plague. It happened in the 6th century and was named after Byzantine emperor Justinian I. It killed over 25 million people over a period of two hundred years (541 C.E to 741 C.E)

The second pandemic – the infamous “Black Death” or the Great Plague – originated in China in 1334 C.E. It then spread to Constantinople (modern Istanbul) before reaching Europe, where it killed 60% of the population.

The third pandemic – also known as the Modern Plague – again in China in the 1860s and appeared in Hong Kong by 1894. It then spread to port cities around the world by rats on ships. It caused approximately 10 million deaths. However, during the third pandemic, scientists were also to determine that plague was caused by a bacterium and was transmitted via flea bites.

After antibiotics were introduced in the 1940s, the mortality rates of plague dramatically went down. Today, less than 200 people die from the plague, which is still prevalent in rural areas of Africa.

Types of plagues

They are three types of plagues

Bubonic plague

This is the most common type that affects a person’s lymphatic system. It gets in name owing to the fact that it causes buboes, swollen and painful lymph nodes under the arms, in the neck, or in the groin. This type is usually transmitted when a person is bitten by an infected rodent or a flea. In some rare cases, a person may get this disease when he/she comes in contact with an infected person. The bacteria spread to other parts of the body if left untreated.

The most common form of plague is the bubonic plague. It’s usually contracted when an infected rodent or flea bites you. In very rare cases, you can get the bacteria from material that has come into contact with an infected person.

Septicemic plague

This type is more dangerous compared to the bubonic plague. Septicemic plague happens when the bacteria move into a person’s bloodstream. The most common symptoms include

  • Bleeding from mouth, nose, bottom, under the skin
  • Blackened skin
  • Stomach ache
  • Diarrhea
  • Vomiting

Pneumonic plague

This is the rarest type and is caused when the bacteria reach a person’s lungs. This type is very contagious as it is spread when the infected person coughs or sneezes. Some symptoms of this disease include

  • Persistent coughing
  • Breathing problems
  • Nausea and vomiting

Causes

Plague is more prevalent in areas with overcrowding, poor sanitation and large populations of rodents (especially rats). It

Yersinia pesti can be transmitted to humans in the following ways

Flea bites

This disease is usually transmitted to people when they are bitten by an infected flea. This happens when a plague outbreak among animals results in the death of many rodents (which are the fleas’ primary host). This prompts the fleas to look at alternate sources of blood. A person or an animal that visits places, where rodents have recently died, are at a high risk of being bitten and infected by fleas.

Contact with contaminated meat

If a person comes in contact with a plague-infected animal, he/she may get the plague. This usually happens when a person comes in direct with an infected animal’s tissue or fluids. For example, a butcher skinning an infected animal without using proper precautions could become infected with the plague.

Contact with infected animals

Cats are very susceptible to plague due to their tendency to hunt and consume rodents. An infected cat can transmit plague via to their owners via droplets. In USA, cats are responsible for many cases of plagues

Droplet infection

This happens when a person breathes in air contaminated with cough or sneeze droplets from an infected person. This, however, only happens when a person comes in direct contact with an infected person. This type of transmission is usually rare in developed countries but is still prevalent in developing countries.

Symptoms

After an incubation period of 2-6 days, most infected people develop flu-like symptoms. The other symptoms of plague are varied depending on the type of infection.

Bubonic plague

Bubonic plague is always characterized by painful, swollen lymph glands, called buboes, which appear in the groin, armpits, neck. Other symptoms may include

  • Fever and chills
  • Headache
  • Muscle pain
  • General weakness
  • Seizures

Septicemic plague

The symptom of septicemic plague usually starts after the onset of the Bubonic plague. Sometimes, the septicemic plague may be fatal even before the symptoms appear. These symptoms can include

  • Abdominal pain
  • Diarrhea
  • Nausea and vomiting
  • Fever and chills
  • Extreme weakness
  • Bleeding (blood may not be able to clot)
  • Shock
  • Blackening of skin

Pneumonic plague symptoms

Pneumonic plague symptoms usually appear very quickly, sometimes even a day after infection. Some of the symptoms may include

  • Trouble breathing
  • Chest pain
  • Cough
  • Fever
  • Headache
  • Overall weakness
  • Blood in sputum

Complications

Plague may cause the following complications

Death: Although the mortality rate of plague has drastically reduced since the development of antibiotics, people who do not receive prompt medical treatment die.

Gangrene: Gangrene is a condition where tissues of the body die due to lack of blood supply. This often happens in the hands and feet. Plague causes blood clots in the tiny blood vessels of the hands and feet. This results in tissue blackening. Tissues affected with gangrene generally need to be amputated.

Meningitis: This is a serious condition which is characterized by the inflammation of the membranes (meninges) surrounding your brain and spinal cord. Although rare, plague causes meningitis.

Diagnosis

Plague can be diagnosed in the following ways

  • Blood test: The doctor will take a blood sample from the suspected patient and analyze it for the presence of Yersinia pesti.
  • Analysis of lymph node fluids: The doctor may also take insert a needle into one of the infected patient’s lymph nodes and analyze it to determine the presence of Yersinia pesti.
  • Bronchoscopy: This is a procedure that lets doctors look at the patient’s lungs and air passages for any signs of pneumonic plague infection.

Treatment

Plague is a life-threatening disease that requires immediate medical care. With no proper treatment, bubonic plague can turn into septicemic plague and pneumonic plague very quickly. A person can die within 24 hours after the appearance of the first symptom. Treatment includes

Antibiotics: Plague is primarily treated by the administration of strong antibiotics such as gentamicin or ciprofloxacin.  With antibiotics, most people get better within a week or two. However, the course needs to be continued for several weeks even after the symptoms resolve.

Quarantine: People with plague (especially the pneumonic plague) should be isolated from other patients.

Prevention

Plague can be prevented by following these measures.

Controlling the rodent population

Rodents are the main vectors of fleas, which may carry the plague bacteria. You can use poisons or traps but doing so may only prove to be a temporary solution. If you want to get rid of a rodent problem once and for all, you’ll need to seal all potential entry points. You should also always dispose waste properly so rodents are not attracted.

Taking the right measures while handling the meat of potentially infected animals

You should always wear gloves while skinning an animal, especially rabbits or some small game. You may contract plague if your bare skin comes in contact with tissues or blood.

Using insect repellents while going camping or hiking

You should always apply insect repellents on the exposed areas of your skin while doing an outdoor activity like hiking, trekking or camping.

Treating your pets for fleas

As fleas are the vectors of plague, you should treat your pets for fleas as soon as possible. If your pet has the habit of roaming freely, it is more susceptible to getting infected fleas. Such pets should not be allowed to sleep on your bed or couch.

Do dead bodies spread plague?

The body of a recently deceased plague victim can infect people who come in close contact with the body. Hence, care should be taken by the people who prepare the body for burial or cremation. The bacterium will mostly be concentrated in the body fluids.

Facts

  • The plague killed an estimated 100 million people (about one-quarter of the population) during the Middle Ages.
  • In 2003, more than 2,100 human plague cases and 180 deaths were recorded

Facts

  • There are fears that plague bacteria possibly could be used as a bioweapon by terrorists.
  • The last plague epidemic in the urban US was in Los Angeles in 1924/1925

Facts

  • The plague has been described in the Old Testament
  • Mass graves of plague victims were recently discovered in an area of Venice called “Quarantine Island.”

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Dos and Don'ts

Dos
  • Always take your full antibiotics course as recommended by the doctor. Do not stop even after the symptoms get better.
  • Always close your mouth or nose while sneezing or coughing to reduce the risk of spreading it to others.
  • Gets pets regularly checked for fleas
Don'ts
  • Panic as the plague is full treatable disease.
  • Go to plague-infested areas without taking proper precautionary measures.
  • Let pets sleep with you if they have fleas

 

 

 

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Find all the instant ways to get rid of blackheads Blackheads - Not only are they aesthetically unappealing but if left untreated these can cause bacterial overgrowth on…
How to correctly perform nasal irrigation using a Neti Pot? Neti pot has been a part of Ayurveda since centuries. This ancient tool is extremely effective in treating…
11 unbelievable health benefits of thyme you didn’t know! Thyme is a herb that has been used in alternative medicine.It is a well known seasoning in the…
Barium-enema
Barium Enema Barium enema is also known as colon x-ray. Here, the patient is asked to consume small amount of…
hepatitis B envelope antigen
Hepatitis B Envelope Antigen (HBeAg) The HBeAg or hepatitis B envelope antigen test is a screening test used to diagnose the onset of…
L-theanine attention
L-Theanine: Better sleep, higher focus, and many other benefits Did you know that L-theanine found in green tea can make you sleep better and be focused at…
kefir bottle
Kefir: Top reasons why this probiotic drink should be consumed by you Yet another remarkable fermented food, kefir is a much healthier version of yogurt. These chewy white grains can…
Agave nectar: The bitter truth about this sweetener revealed Agave nectar is considered to be sweeter than the normal table sugar and even contains higher amounts of…
Bromelain: 11 reasons why you should start adding pineapple to your pizza! If you didn't love pineapples already, here are some of the top health benefits that bromelain can bring…
Tattoo Aftercare: The best practices to follow once you get inked Planning getting permanently inked? Make sure you follow these critical tattoo aftercare techniques to avoid infectious agents attacking…
How accurate is the hair follicle drug test? Hair follicle drug test is one of the best ways to identify drug use in professional circles. But…
Inversion Therapy: The anti-gravity way of healing chronic back pain Inversion therapy involves suspending a person upside dow using different types of equipment. This works by taking the…
thyroid_scan
Thyroid Scan Thyroid scan is a diagnostic procedure that aims to view the thyroid gland and detect any growths or…
lp-pla2
LP-PLA2 Test The LP-PLA2 test is a test which is carried out to assess the levels of Lipoprotein-Associated Phospholipase A2…
complement c4 test
Anemia Profile Anemia Profile test (Basic) is a blood screening test that measures the levels of important components of the…
immunoglobulin M
Immunoglobulin M Test Immunoglobulin M is the largest and the first produced antibody which helps in the prevention or fighting of…
macadamia nuts in food
Proven health benefits and nutrition of macadamia nuts Know all about scientific, amazing health benefits of macadamia nuts, its nutrition, recipes, how to consume, price and…
macadamia nuts in food
Proven health benefits and nutrition of macadamia nuts Know all about scientific, amazing health benefits of macadamia nuts, its nutrition, recipes, how to consume, price and…
fitness routine fun
10 fantastic ways to make your fitness routine more fun! Are you too bored to exercise? Do you avoid gym cause it's too monotonous? Looking for fun and…
sleep deprivation
Don’t let your sleep deficit grow into memory loss or heart attack Why is sleep important for us? How could sleep deprivation harm you? We bet you didn't know about…
The complete “what to eat” guide for gluten intolerance Does eating breads and pastas often makes you nauseous? Gluten intolerance is a common reason why you might…
Pescatarian Diet 101: What are the inherent health advantages of this diet? People opt to become a pescatarian in order to enrich their bodies with the essential health benefits that…
Oxidative Stress: Understanding the most lethal phenomenon happening in your body right now Free radicals cause damage to the body, which is known as oxidation.  The amount of oxidation caused by…
Tamarind: The top health benefits of this staple Asian ingredient Did you know this sweet and sour pulpy fruit does more than just add a tangy flavor to…
Oxalates: How healthy greens can sometimes be bad news for your kidneys Oxalates are compounds present in a majority of healthy foods. However, at times an overconsumption of these could…
SIBO Diet: The important dos and don’ts of this gut-healing diet A SIBO diet is a diet that works by eliminating certain sugars from your diet and adding fibers…
Internal bleeding brain
Beware: Ignoring these tell-tale signs of stroke could cost a life The signs and symptoms of a stroke differ depending on which part of the brain has been affected.…
Bubble Tea: Bubbling with nutrition or a hidden sugar mine? The tapioca pearls present in the tea looks like bubbles and hence the name bubble tea became popular.…
GGt test
GGT – Gamma-Glutamyl Transferase Test GGT or gammaglutamyl transferase test is a liver function test that is used to detect the extent of…