Infertility

Infertility woman

Last Updated December 20th, 2021

Overview of infertility

Reproduction is a very important stage in the life of a human being. It not only completes the biological cycle of life, but also contributes to the development of a family and the society. In the recent years, there have been marked evidence of incontinence in both males and females worldwide which has led to the increased number of “infertility” cases. According to the global statistics of the World Health Organization, nearly 60-80 million couples in the world are infertile. Various environmental, physiological and psychological factors can lead to these conditions. Infertility is not only a problem of an individual but is also a social crisis, since it directly affects the rate of childbirth in a given population.

 

What is infertility?

Infertility manInfertility is medically defined as the inability to reproduce even after one year of unprotected sexual intercourse.

In some cases, it refers to the condition in which a woman is capable of conception, but is unable to continue the pregnancy.

Women who are 35 or older should consider infertility if they are incapable of conception after 6 months.

All these cases need adequate medical attention.

 

The common misconceptions

The traditional myth indicates that a woman is entirely responsible for the absence of childbirth. While that is possible in some cases, in one-third of the cases men are fully responsible for the lack of conception. Women also contribute to infertility in one-third cases. In the remaining one-third cases, infertility is caused by a number of extrinsic and intrinsic factors. In the following section, the causes of infertility in men and women will be discussed separately.

 

What causes infertility in women?

Infertility womanInfertility in women is caused by the following factors-

  • An inadequate or complete absence of ovulation, which inhibits the generation of eggs that need to be fertilized
  • Irregular menstrual cycles with heavy bleeding
  • Polycystic Ovarian Syndrome, which leads to ovarian insufficiency
  • Hormonal imbalance (fluctuation in the level of estrogen)
  • Early menopause
  • Increased age (above 40) which causes reduced reproductive capacity of the woman (Eg: Deterioration of uterine lining)
  • Production of insufficient eggs due to existing medical conditions or past surgeries
  • Obstruction of the fallopian tubes due to pelvic inflammatory disease, endometriosis or past surgeries
  • A history of ectopic pregnancy, miscarriage or septic abortion
  • Anatomical defects of the uterus (causes reduced capacity of the uterus to hold the foetus till birth)
  • Absence or deficiency of cervical mucus that helps in sperm motility
  • Presence of aggregated muscles and tissues (uterine fibroids) on the walls of the uterus (inner lining of the abdominal organs)
  • Infections of the reproductive tract caused due to genital mutilation
  • Presence of adhesions (scar tissues) on the peritoneum
  • Production of poor quality, unhealthy and insufficient eggs
  • The occurrence of sexually transmitted diseases like AIDS, Gonorrhoea etc
  • Pathological diseases like Tuberculosis, Sickle cell disease or Malaria
  • Weight problems (obesity or underweight conditions)
  • Emotional and physical stress on a regular basis
  • Poor dietary habits (deficiency of essential vitamins and micronutrients)
  • Addictive habits like alcoholism and smoking
  • Rigorous athletic training
  • Poor sexual hygiene, having multiple sexual partners or engaging in sexual activities from a very young age.

 

What causes infertility in men?

Male infertility is caused by a number of factors described below-

  • Erectile dysfunctions
  • An acute medical condition known as Variocele, wherein the testicle gets heated up due to the presence of extremely large veins on it (affects the quality and quantity of the sperms)
  • Generation of insufficient sperms
  • Problems in sperm motility caused by abnormal sperm shape or obstruction of the sperm
  • Medical conditions like cystic fibrosis
  • Anatomical defects of the testicles (Eg: Cryptorchidism, Hypoplasic testes) and other parts of the reproductive tract
  • Obstruction of sperm movement due to enlarged prostate or vasectomy
  • Damage of testicular nerves
  • Degeneration of the sperms with age
  • Existing medical illnesses like Diabetes, kidney diseases, Pubertal Mumps, Filariasis or some hormonal problems
  • Insufficient production of testosterone
  • Hormonal disturbances caused due to pituitary tumours or excess intake of steroids
  • Autoimmune disorders which lead to the formation of sperm antibodies
  • Genetic diseases such as Down syndrome or Klinefelter’s syndrome
  • Surgical procedures such as vasectomy
  • Direct exposure to toxic chemicals like lead, asbestos etc due to an occupational requirement
  • A high intake of a few over-the-counter medications (Eg: Cyclophosphamide used for the treatment of kidney diseases)
  • Unprotected exposure to ionizing radiations in the course of the treatment of some other disease (Eg: Cancer)
  • Excess intake of alcohol and tobacco

 

What are the main symptoms?

The common symptoms of infertility in men are as follows-

  • Production of less semen
  • Reduced sexual desire
  • Inability to maintain an erection
  • Unexplained tiredness during sexual intercourse

Below is a list of female infertility symptoms

  • Painful sexual intercourse
  • Irregular and heavy menstrual bleeding
  • Lower abdominal pain

 

What are the different types of infertility?

Classification of infertility depends mainly on the time of infertility. The major subtypes of infertility are as follows-

  • Primary infertility: Primary infertility is the inability to reproduce in the entire lifetime. It usually results from structural defects of the reproductive organs or some chronic diseases.
  • Secondary infertility: Secondary infertility is the inability to give birth for a second or third time. In this case, the women experience and sustain pregnancy in the past. But reproduction does not take place in the later stages due to aging or chronic diseases. In some cases, women who have a history of miscarriage or ectopic pregnancy experience difficulty getting pregnant during the second or third time.

 

What are the common diagnostic tests?

The exact cause of infertility is difficult to detect. These two laboratory examinations can help detect the root causes-

  • Hysterosalpingography and Laparoscopy (for women)
  • Semen analysis, Karyotype test (for men)

 

Treatment & Prevention

Infertility IVFThe treatment modality depends on factors such as the cause of infertility, the duration of being infertile, the age of both the sexual partners, personal preferences etc. In some cases, the cause of infertility cannot be rectified.

Treatment for Males

The treatment modalities for males involve therapy for the lack of healthy sperm or for general sexual problems. Some methods are as follows:

  • Lifestyle and behavioral changes- Some changes can be increasing the frequency and the timing of intercourse, eliminating harmful factors, stopping certain medications, exercising regularly and taking care of factors that may otherwise affect fertility.
  • Medication– Certain medications augment testicular function, sperm production, and quality. This improves the sperm count for achieving a successful pregnancy.
  • Surgical intervention: In some cases, surgeries are performed in order to undo a sperm blockage and restore fertility. However, some cases involve the surgical correction of a varicocele in order to perk up the overall probability for pregnancy.
  • Sperm retrieval– These techniques are usually employed in problematic ejaculation or in absence of sperm in the ejaculated fluid.

Treatment for Females

The different kinds of therapies for females are as follows:

  • Stimulating ovulation with fertility drugs- These medications help in inducing or regulating ovulation. This type of medication is the treatment of choice for females infertile due to ovulation disorders.
  • Intrauterine insemination (IUI) – In this technique, a healthy sperm is positioned in the uterus around the time of ovulation. The timing of IUI is coordinated with the normal cycle or the fertility medications taken by the female.
  • Hysteroscopic surgery– These surgeries are performed with the aim to rectify uterine conditions such as a uterine septum, endometrial polyps or an intrauterine scar tissue.

Assisted reproductive technology (ART) and other techniques such as intracytoplasmic sperm injection (ICSI), assisted hatching, gestational carrier method etc. are employed depending on the case.

Infertility can be prevented in many cases by adopting a healthy lifestyle, managing stress and treating the underlying conditions.

 

Dos and Don'ts

Dos
  • Adopt a healthy lifestyle. Be physically active and chose healthy eating options. An optimum amount of rest and sleep are essential to de-stress the brain and perk up your overall health.
  • Manage the emotional stress. Not achieving pregnancy or having a miscarriage can be stressful. Talk to your partner, family, and friends regarding your emotions.
  • Consult your gynecologist regarding the complications ART can cause. Complications such as bleeding, infection, multiple pregnancies might occur.
Don'ts
  • Indulge in smoking. Smoking substantially reduces the fertility in males and females.
  • Have alcohol consumption. Alcohol (even in small quantities) affects the chances of conceiving.
  • Neglect obesity. Obesity increases the chances of infertility in males and females.

 

 

 

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Jack in the box fast food
Jack In the Box : The perils of surging fast food culture in the USA Jack in the Box - How a culture of fast-food can clog your arteries, weaken your heart, fatten…
Love tea, hate tannins? Rooibos tea is just what you need The market is brimming with a multitude of herbal teas. But what makes rooibos tea (or red bush)…
Is bronchitis contagious? And how to prevent this infection? It is acute bronchitis that is contagious which means you can contract it from another person or you…
cytomegalovirus iGG
Cytomegalovirus (CMV)- IgG Test The cytomegalovirus IgG is the immunoglobulin protein produced by our immune system when the body is infected by…
woman with abdominal pain holding ovulation calendar
Ovulation – facts to know about ovulation Learn how and when ovulation occurs, demystify common misconceptions, identify symptoms, methods of detection and right period for…
phenytoin test
Phenytoin test Phenytoin is a drug that is administered mainly to epilepsy patients. The phenytoin blood test measures the level…
Tissue Transglutaminase Antibody (tTG) Test Transglutaminase is an enzyme present in our body and is involved in protein metabolism. A tTg test is…
Chlorella: Therapeutic powers of the billion-year-old algae now within your reach Chlorella - A billion year old nutrient-rich algae that can potentially ward off cancers and high cholesterol; the…
Okra: How can this nutrient-dense vegetable help you fight diabetes? Okra is a food which is rich in nutrients and minerals which are extremely essential for a healthy…
tonometry
Tonometry Tonometry uses a device called tonometer to measure the pressure inside the eye. This pressure is depends upon…
dhea adrenal
Androstenedione Test Androstenedione is produced by the adrenal gland, the test of the levels of Androstenedione helps in the evaluation…
GM Diet: The fastest way to lose weight or yet another hoax diet? General Motors started this trend of extreme dieting for 7 straight days to ensure its employees were able…
How can Kegels help you overcome weak pelvic muscles & incontinence? Kegel exercises are pelvic floor strengthening exercises that can help you overcome incontinence issues that rise out of…
rosacea-treatment--before-_-after
The best and safest ways to treat rosacea Rosacea is a skin disease that is characterized by reddish hives and rashes on the face. Read more…
about mediterranean diet
Why you should be adopting a Mediterranean style of diet today Ever wondered why the Mediterranean diet is so healthy? One simple solution to lowering risk of several deadliest…
CERULOPLASMIN- triple marker
Triple Marker Test A triple marker test is an important prenatal test that is performed to detect the presence of chromosomal…
working mom with kids
Practical Motherhood Tips for Working Women Check out these effective tips for working mothers to manage motherhood and work life. Raise your children easily…
kidney stones
Kidney stones Kidney stones are solid substances made up of crystals. They can be of various sizes. Treatment depend on…
Bubble Tea: Bubbling with nutrition or a hidden sugar mine? The tapioca pearls present in the tea looks like bubbles and hence the name bubble tea became popular.…
shakeology woman
Meal replacement or protein drink? Learn all about Shakeology and its claims Shakeology from Beachbody claims to be the most suitable shake that can aid in weight loss, regulate blood…
BRAT Diet: What is the right way to follow this diarrhea-relieving diet? BRAT diet, a simple diet consisting of just bananas, rice, applesauce, and toast, can help you combat the…
Coffee Enema: Turn your favorite morning beverage into a powerful colon cleanser The wonders of coffee are not just limited to waking you up every morning. You can now use…

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