Androstenedione Test

dhea adrenal

Last Updated December 20th, 2021

What is Androstenedione?

Androstenedione is a hormone belonging to the androgen group which is one of the most integral male sex hormones.  Even though it is a male hormone, it is also found in females especially the premenopausal women.

Androstenedione is a precursor androgen which is converted by the body into a more potent or active form like testosterone in males and estrogen in females. The production of the Androstenedione happens in the ovaries in females and in the testes for the males.

The production of the Adestenedione in the ovaries and testes is regulated by the pituitary hormone called LH(Luteinizing Hormone). The ACTH(AdrenoCorticotropic Hormone) is responsible for the regulation of the secretion of the Androstenedione by the adrenal glands.

What is the Androstenedione test?

Androstenedione test is used to measure and monitor the levels of the Androstenedione in the blood. The levels of the Androstenedione is variable diurnally as well as during the menstrual cycle of a woman.

Why did my doctor recommend me the Androstenedione test?

The Androstenedione test can be used for the diagnosis of various conditions. If your doctor has recommended you to undergo the Androstenedione test, for the following reasons as listed below.

– Since the Androstenedione hormone is produced by the adrenal gland, the test of the levels of the Androstenedione helps in the evaluation of the functioning of the adrenal gland. Your doctor might suggest you undergo the Androstenedione test for assessing the functioning of the adrenal glands.

– The Androstenedione acts as the tumor marker for the adrenal gland. Your doctor might recommend the Androstenedione test if he wants to diagnose any malignancy in the adrenal glands.

– If your doctor wants to diagnose the reasons for the early puberty, he might suggest you undergo the Androstenedione test.

– The reasons for the development of the male characteristics in females(virilization) like facial hair etc are also diagnosed using the Androstenedione test. Your doctor might recommend the Androstenedione test for the same.

– Your healthcare practitioner might need to evaluate the functioning of your testes and ovaries. Hence, you have been recommended to undergo the Androstenedione test.

– To diagnose the Congenital Adrenal Hyperplasia(CAH) or to evaluate if your body is responding to the CAH treatment, your doctor can suggest you undergo the Androstenedione test.

When should I go for the Androstenedione test?

There are various symptoms related to the abnormal levels of the Androstenedione. If you have been experiencing such symptoms, it is always suggested to undergo the Androstenedione test. Some of the common symptoms are as follows:

– Excessive body hair and facial hair growth in females(Hirsutism).
– Missing menstrual periods every month(Amenorrhea).
– Getting lesser than 6-8 menstrual cycle per year (Oligomenorrhea).
– Infertility
– Early or late puberty in both males and females.

If you are experiencing various symptoms of CAH(Congenital Adrenal Hyperplasia), it is significant to undergo the Adrenostenedione test. The common symptoms of the CAH are:

– Dehydration
– A sudden shift of appetite
-Diarrhea
-Frequent vomiting and nausea
-An irregular rhythm of the heartbeat
-Low blood pressure
– Very low blood sodium levels
– Having very low blood glucose levels.
-Acid toxicity in the blood (metabolic acidosis)
– Abrupt weight loss
– Difficulty in concentration
 

What are the preparations required for the Androstenedione test?

There are no specific preparations required for the Androstenedione test.

– Fasting is not required.
– No new medications are included.
– All the old medications can be continued. Consult with your doctor and tell him about all the medicines that you had been taking. He might suggest you stop certain hormonal medications which can affect the results.
– The specimen is collected generally in the morning.
– In the case of menstruating women, the specimen of blood is collected 1 week before or after the menstrual cycle.

What is the procedure of the Androstenedione test?

The  Androstenedione test is conducted by the blood sample collection. The blood sample is collected by the procedure of venipuncture. The process of venipuncture is done by the following ways elaborated in the steps below:

– A tourniquet or a tight elastic band is wrapped around the upper arm of an individual. This makes the veins more prominent making it easier to locate the vein to withdraw the blood sample from.

– A syringe or a needle is injected into the vein from which the blood sample is withdrawn.

– The blood sample is collected in the tube of the syringe. The tourniquet is unwrapped and an antiseptic is applied on the spot of the puncture. The spot of the puncture is dabbed with a cotton swab or a bandage is put. This helps in stopping any further bleeding.

– The collected blood sample is then sent to the laboratory for the Androstenedione test.
 

Is the Androstenedione test painful?

The Androstenedione test is conducted by the collection of the blood sample. The blood sample collection is done in the safest way called venipuncture. This procedure of the blood collection might involve a pinpricking sensation when the needle gets injected. This feeling fades away in a few hours or a day maximum.
 

What are the risks associated with the Androstenedione test?

There are no risks associated with the Androstenedione test. The procedure of the blood collection involves some minute risks.

– One can experience pain due to so many punctures. This pain wears off in some time.

– Some people might feel lightheaded and dizzy after the collection of the blood sample.

– There’s a chance of Haematoma(clotting of blood under the skin forming lumps).

– Bruising and bleeding are the most common risks associated with the Venipuncture procedure.
 

What is the price of the Androstenedione test?

The price range of the Androstenedione test in India starts from Rs 1800 It might vary depending on the location of the diagnostic center i.e. the city or the state the diagnostic center is located in.
 

When will I get my results for the Androstenedione test?

You will get your results for the Androstenedione within 24 hours to 36 hours of the test.

How to understand my results for the Androstenedione test?

Age (male) Clinical reference(in nmol/L)
18 – 30 years 175-768
31 – 50 years 140-663 
51 – 60 years 175-768


Menstrual Stages (females) Clinical reference(in nmol/L)
Follicular  122-873
Mid-cycle  209-995
Luteal  105-820
Postmenopausal 70-262


Age (children) Clinical reference(in nmol/L)
1-12 months 21-272
1-4 years 17-178
5-9 years 21-401 
10-13 years  42-771
14-17 years  77-785

What does it mean if I have higher levels of the Androstenedione?

If you  are a female and you have a higher level of Androstenedione in your blood, it indicates the following conditions:

– Excess growth of body hair (hirsutism)
– An abnormal pattern of menstrual periods or irregular menstrual periods.
– Early puberty
– PCOS(PolyCystic Ovarian Syndrome)
– Virilization(development of  male characteristics)
– Amenorrhea(missing out monthly periods or getting lesser than 4-6 menstrual periods throughout the year) 
– Adrenal tumors 
– CAH(Congenital Adrenal hyperplasia)

If you are a male, the signs and symptoms of the increased level of the Androstenedione are not noticeable. The most common things indicated by the higher levels of the Androstenedione in males are:
– Adrenal tumors 
– Adrenal glands failing to work properly
– CAH(Congenital Adrenal Hyperplasia)

What does it mean if I have lower levels of the Androstenedione?

If you are a female with the levels of Androstenedione lower than the clinical range according to your age and phase, it can indicate the following conditions:

– The incapability of the adrenal glands to work the way that it should.
– Previous surgical removal of the ovaries in a female.
– Hypopituitarism(the condition in which the pituitary gland does not produce the hormones required in the correct amount).
– Early menopause
 
If you are a male with the levels of the Androstenedione lower than that of the clinical range according to the age, it indicates the following conditions:

– Addison’s disease or primary adrenal insufficiency in which the adrenal glands stop functioning the way it is required to work.
– In the case of late puberty, the levels of the Androstenedione is very low.
– CAH(Congenital Adrenal Hyperplasia)
– Dysfunction of the pituitary gland because of the tumors.
– Kallman syndrome (this condition signifies the abnormal development of the hypothalamus which is a hormone controlling gland in the brain).
– The incapability of testes to produce enough Androstenedione.
 

Is the Androstenedione test recommended during pregnancy?

Androgens play a very pivotal role during the gestational period. The abnormal levels of the Androgens have adverse health effects on the fetus. Hence, it is very important for pregnant women to undergo the tests for androgens. You need to undergo the test for the Androstenedione which is a type of androgen hormone along with the other androgen tests if your doctor recommends it according to your other health conditions.   

Is the Androstenedione test recommended for my newborn?

There are various effects of the abnormal levels of the Androstenedione on the kid. It is highly recommended for your newborn to undergo the Androstenedione test if a condition of ambiguous external genitalia is noticed. Under this condition, the higher levels of the androstenedione and other androgens lead to the newborn to have sex organs which not clearly male or female.

When should I take my kid for the Androstenedione test?

If your kid is experiencing early or late puberty, it’s highly recommended for your kid to undergo the Androstenedione test. 
In the case of experiencing the symptoms of CAH(Congenital Adrenal Hyperplasia), your kid is suggested to take the Androstenedione test. Some of the common symptoms of the CAH(Congenital Adrenal Hyperplasia) are listed below-

In the case of a female child, the common symptoms of CAH might be as follows:

– A deep and husky voice like males
– Excess growth of hair on the face and body
– Missing out monthly menstrual periods or irregular periods
– Changes related to early puberty such as hair in the armpits and pubic area
– Severe acne and pimples problem.
– Male-pattern baldness (loss of hair near the temples)
 
In the case of a male child, the symptoms of the CAH might be as follows:

– Development of muscles at an early age
– Early puberty with the early growth of armpit hair and pubic hair.
– Enlargement of the penis during childhood
– Deepening of the voice earlier than the age of normal puberty
– Early growth of beard
– Smaller testicles than normal
– Severe acne and pimples

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antinuclear antibody test
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8 hidden causes of obesity you probably didn’t know! Did you know that around 2 billion people worldwide are either overweight or obese? Are…
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11 unbelievable health benefits of thyme you didn’t know! Thyme is a herb that has been used in alternative medicine.It is a well known…
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Exercises or diet? Find out the healthiest way to gain weight Tired of being called skinny all the time? Looking for healthy ways to beef up?…
Pulmonary Function Tests Pulmonary function tests (PFT’s) are non-invasive breathing tests employed for diagnosing and monitoring lung diseases…
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Coconut Oil: How one oil dominates the kitchen and the medicine kit too Coconut oil has been a favorite in many Asian kitchens. But more than a cooking…
Epley maneuver: Why is this the best protection from the symptoms of vertigo? Epley maneuver is an exercise that can treat the symptoms of benign paroxysmal positional vertigo…
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Blood Sodium Test A blood sodium test measures the amount of sodium (an important electrolyte) in your body.…
CT-scan-machine
CT – Computed Tomography Scan CT scan or computed tomography scan is an diagnostic imaging technique where cross-sectional images of…
dance health benefits
5 unbelievable effects of dance on your overall health! You enjoy dancing, but did you know what else it does to your body? Dancing…
Coconut sugar: What is it and is it healthier than table sugar? In the long list of things that the wonderful coconut gives us, coconut sugar is…
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Troubled with IBS? Here’s a complete roadmap to the low FODMAP diet Leaky & inflammatory gut troubling you? No medicine bringing you relief from the pain? Why…
Gynecomastia breast reduction surgery
Breast Reduction Surgery Breast reduction or reduction mammoplasty is a reconstructive procedure to reduce the size of large…
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Minimally Invasive Total Knee Replacement Unlike traditional knee replacement, a minimally invasive total knee replacement uses a shorter incision to…
Cordyceps: How the Caterpillar fungus works as a proven cancer-shield Strange as it may sound, but cordyceps or "caterpillar fungus", a fungus variety native to…
Sciatica pain relief: Get rid of the pain with these easy daily tips Researchers have claimed that not only heat but icing the area too helps relieve sciatica…
Yerba Mate: Could the national drink of Argentina successfully replace coffee? Yerba Mate is used for making tea-like beverage which contains caffeine. It is a herb…
Anti-Inflammatory foods: 18 foods to a disease-free you Anti-inflammatory foods are the foods which are known to reduce the inflammation as well as…
kefir bottle
Kefir: Top reasons why this probiotic drink should be consumed by you Yet another remarkable fermented food, kefir is a much healthier version of yogurt. These chewy…
canola oil cooking
Canola oil: How safe is it to consume this popular cooking oil? Extracted from rapeseeds, Canola oil derives its name from Canadian Oil. Did you know that…
Legumes: Little pods of infinite nutrition you should consume daily The fruits and seeds of Fabaceae type of plants are called legumes.The most commonly used…
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What does hypoglycemia look like when you don’t have diabetes? Hypoglycemia is not just a disease that co-occurs with diabetes. Non-diabetics could also become hypoglycemic.…
Vitamin K2: 8 reasons why you need this bone-building & cancer-fighting nutrient Vitamin K2 is claimed to be essential for your bone health, for reducing the risk…
How can Kegels help you overcome weak pelvic muscles & incontinence? Kegel exercises are pelvic floor strengthening exercises that can help you overcome incontinence issues that…
Jicama: A fiber-rich tuber for your weight loss goals Pronouced as HEE-kah-ma, Jicama is the "new kid on the block" that has taken the…
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Free thyroxine test (FT4) The FT4 or free thyroxine test is used to detect the level of free thyroxine…
Anhedonia: Does the chronic inability to feel joy affect you too? How often do you feel dragged down by an invisible force? Do you feel an…
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Burpees: World’s most challenging fitness routine now made simple for you The majority of the fitness regimens mainly concentrate on a particular muscle group whereas Burpees…
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FSH (Follicle Stimulating Hormone) Test The FSH or follicle stimulating hormone test is an important diagnostic tool used to determine…
alpha feto protein test
Alpha Feto Protein (AFP) Test AFP or alpha feto protein is a specific protein which is formed only in the…
18 instant steps to make your jogging routine more powerful Jogging is a form of Aerobic Endurance training which includes running at a slow pace.…
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10 Common signs you need to see a mental health counselor now Read to know if you have any of these 10 sure-signs that say you need…
Nootropics: How safe are these drugs that make you smarter? Nootropics is a group of cognition-enhancing substances that facilitate better learning, memory, and other executive…
Top Natural Repellents for Mosquitoes with negligible side-effects What are the best ways to keep mosquitos away from you? Try these natural and…
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Top natural diuretics: The instant benefits you can get from nature’s water pills Since diuretic drugs are known to cause side effects, it is better to choose a…
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Easy steps on how to do the plank for the perfect abs The plank exercise helps in several ways like strengthening your abs, shoulders, back and glutes.…
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MCT Oil : The kind of fats you should be eating MCT oil or Medium Chain Triglycerides is the new buzzword in the fitness industry. What…
From treating insomnia to joint aches, discover how eucalyptus extract can help you The oil of eucalyptus with its wide array of benefits has been on the herbal…
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Lung Transplant Lung transplant is a procedure to replace one or both lungs that are diseased with…
These are the top foods to increase your hemoglobin count It is important to add iron-rich foods into your diet in order to increase hemoglobin. Deficiency…
Jackfruit: Slice your way into higher immunity, better digestion, & more… Native to the South East Asia, the jackfruit is a fruit brimming with thousands of…
Tomato: All you need to know about this juicy vegetable (or a berry?) Do you know why tomato is scientifically categorized as a berry? Or why do cardiologists…
Inversion Therapy: The anti-gravity way of healing chronic back pain Inversion therapy involves suspending a person upside dow using different types of equipment. This works…
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Carrageenan: How a simple seaweed extract could better your gut health & immunity Eat more ice cream to prevent cold and flu? –With carrageenan you get one simple…
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Anti-Hepatitis B Core Antigen (AHBc) Total Anti-hepatitis B core antigen (AHBC ) is a blood examination and the only serological marker…
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Varicose veins Varicose veins are swollen, twisted blood vessels. They can cause immense pain and discomfort. Some…
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Iron Deficiency Profile An iron deficiency profile is a battery of blood tests which are performed in order…
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BCAA: Now get more out of your workouts with this miracle protein BCAAs are counted as one of the best supplements for increasing your physical endurance. Find…
Chromium Picolinate: An essential mineral supplement for faster weight loss Did you know that about 1.6 million deaths were directly linked to diabetes globally? How…
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Ureteroscopy Ureteroscopy is the diagnostic procedure which is used for the detection of the kidney stones…
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6 arguments in favour of glucosamine and where can you find it Studies have shown that glucosamine works by preventing the breakdown of cartilage of the joints.…
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Anti Ds-DNA antibody Test The  Anti Ds-DNA antibody test is used to diagnose the disease called lupus or more…
What to eat, what not to eat in the South Beach Diet? The South Beach Diet is one among the most popular weight loss programs that have…
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Lauric Acid: 8 health benefits you can derive from coconuts Appropriate use of saturated fats containing lauric acid can provide you numerous health benefits. This…
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Apple cider vinegar: Weight loss, shinier hair, and more! Did you know that apple cider vinegar, produced by the simple fermentation of apple juice,…
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Bulletproof Coffee – Breakfast of champions or yet another health fad? Can this special ketogenic coffee really make your body race as fast as a bullet?
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Avocado: 15 reasons why this fruit should be a staple in your diet Did you know that the word avocado literally means "testicles". Don't get grossed out as…
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GM Diet: The fastest way to lose weight or yet another hoax diet? General Motors started this trend of extreme dieting for 7 straight days to ensure its…
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The features of an Optavia diet The Optavia diet endorses pre-packaged meals and snacks called "fuelings" that are tasty, low in…
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Beware: Ignoring these tell-tale signs of stroke could cost a life The signs and symptoms of a stroke differ depending on which part of the brain…
Sushi: health benefits and recipes Sushi is a traditional Japanese dish prepared with vinegared rice served with fish (often raw),…
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Testosterone test Testosterone is the primary sex hormone in males; produced in the testes and adrenal glands.…
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Paleo Diet: Is eating like the Caveman the right way to go? Paleo diet is the world's oldest diet; dating back to 2.5 million years ago. Why…
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