Zifi 200

Bronchitis nebulization

Therapeutic Indications for Zifi 200

Zifi 200 mg Tablet can effectively tackle bacterial infections. A broad-spectrum antibiotic, Zifi exerts this effect by controlling the growth of bacteria and destroying it.This medicine comes under the class of drugs called ‘Cephalosporin anti-bacterials.

Zifi 200  is an oral third-generation drug   This anti-bacterial medicine destroys bacteria by targeting the way bacteria build their cell walls, thus controlling their growth. Zifi 200 is ineffective against viral infections, for instance, flu and the common cold.

Zifi 200 treats

  • Lung infection such as bronchitis (effective even in worsening cases of bronchitis)
  • Urinary tract infections
  • Sexually transmitted infections like Gonorrhoea affecting rectum and urethra
  • Ear infection
  • Bacterial Meningitis
  • Throat infection like tonsillitis and pharyngitis
  • Bacterial Septicaemia
  • Pneumonia
  • Bone and joint infection
  • Skin infection

 This medication comes in the form of chewable tablets, capsules and oral suspension

Do I need a prescription?

Zifi 200 mg is available in most of the drug stores and pharmacies. You need a prescription from a qualified healthcare professional to purchase Zifi 200 mg.


Zifi 200 mg tablet

  • Tablet , capsule and chewable tablets are  available in strengths of 100 mg, 150 mg, 200 mg, 400 mg
  • Oral suspension is available in strengths  of  100mg/5 ml, 200 mg/5 ml, 500 mg/5 ml
  • You can take this drug without/with food
  • Follow the dosage to the detail. Refrain from taking smaller or larger quantities than recommended
  • Do not abruptly stop taking the medicine before the treatment course is over
  • Always store Zifi 200 in an airtight container at room temperature. Make sure to keep in a safe place away from children.
  • Healthcare professionals always consider age, weight, health conditions, health of liver, as well as medicines/supplements taken by the patient before fixing the dosage for Zifi.

Adult dosage

Urinary Tract Infection:  Zifi 200 mg oral intake. Repeat the dose every 12 hours

Ear infection: 200 mg oral intake, 12 hourly dosages

Tonsillitis/Pharyngitis:  Zifi200 mg orally every 12 hours

Chewable tablets: 400 mg oral intake once a day

Bronchitis:  400 mg orally once a day or split as 200 mg 12 hourly

Gonococcal Infection : 200 mg oral intake as a single dose

Child dosage Zifi 200mg (6 months and older)

  • Zifi 200 is not permitted for children below 6 months of age.
  • To ascertain precise dosage for your child, use the weight based dose calculator to know the correct dosage based on your child’s weight

Severe  bronchitis :Children (6 months or older): 8 mg per kg/3.6 mg per lb. of body weight daily for oral suspension. Children (children over 12 years or weighing more than 50 kg): 400 mg daily

Sexually Transmitted DiseasesUrinary tract infection: Children (6 months or older): 8 mg per kg/3.6 mg per lb. of body weight daily for oral suspension. Children (children over 12 years or weighing more than 50 kg): 400 mg/day

Pharyngitis or tonsillitis: Children (6 months or older):8 mg per kg/3.6 mg per lb. of body weight daily for oral suspension. Children (children over 12 years or weighing more than 50 kg): 400 mg daily

Middle ear infections: Children (6 months or older):8 mg per kg/3.6 mg per lb. of body weight daily for oral suspension. Children over 12 years: Recommended: 400 mg daily

Sexually transmitted infections (gonorrhea)Children (6 months or older):  8 mg per kg/3.6 mg per lb. of body weight daily for oral suspension.Children (children over 12 years or weighing more than 50 kg): 400 mg/day

Chemical composition

The active ingredient in Zifi 200 is Cefixime

Mechanism of Action

The key ingredient Cefixime in Zifi 200 works interfering in the formation of cells of the bacteria. Zifi takes the role of a bactericidal; it latches on to the penicillin binding proteins and hampers fusion with the cell wall. Zifi 200 is at its peak performance within 3-4 hours of taking the drug. The effect usually lasts for about 20-36 hours.


Zifi 200 can cause adverse reaction in the presence of certain health conditions, or with other medication, vitamins and herbs. It is imperative to let your doctor know about your medical history including the medicines and supplements you are taking to avert a potential interaction with this drug.

Adverse reactions

Hemophilia bleedingBleeding disorders: Victims of bleeding disorders need to be extremely careful, as there is an enhanced risk of excessive bleeding. Healthcare professionals advice closer watch on clotting time and necessary dose iteration in the event of side- effects. In worst cases, alternative medicine may be better to avert any potentially life-threatening situation.

Colitis: Victims of colitis or other forms of gastrointestinal problems should tread carefully with intake of Zifi 200.  Such patients have reported exacerbation of symptoms, for instance- severe pain, blood in stools, and diarrhoea

Seizure disorders: Victims of any seizure disorder need to exercise caution with intake of Zifi200

Paediatric Use:  Use this medicine with extreme caution in children below 12 years of age. Usually doctors do not prescribe tablets. Only chewable tablets or oral suspension can be used for children this age group.

Situational Precaution

Driving: Some patients have reported dizziness after taking Zifi 200. It is better to avoid driving at least during the course of treatment.

Working with machinery:  Operating machinery while on this drug can turn risky in the event of dizziness.

Facts on Zifi 200

  • Zifi O is a combination of drug doctors prescribe to treat typhoid and urinary tract infection in adults.
  • Zifi CV 200 Tablet is a combination medicine containing Cefixime (200 mg) + Clavulanic Acid (125 mg)that combats bacterial infections effectively
  • Zifi 200 may lower platelet count, therefore bruising and injury is a risky affair
  • This medicine may reduce platelet count, avoid injury or bruising.
  • Zifi 200 MG Tablet fights osteomyelitis and septic arthritis. It also treats cutaneous abscess and skin/structure infection, for instance, cellulitis.
  • Zifi 200 is thrown out of the body through feces and urine
  • This drug has been approved for use on Japan, India And United States
  • Zifi 200 is not an addictive or habit-forming  drug

Drug interactions

The following drugs can trigger severe reaction with Zifi 200 intake.  It is better to ascertain the safety of this drug if you are on any of these medications. In addition, if you are allergic to any of the ingredients in Zifi 200, it is better to avoid this drug.

  • Ethanyl Estradiol
  • Chloramphenicol and Amikacin
  • Allergy to beta-lactam antibiotics like Penicillins and Cephalosporins
  • Furosemide
  • Nifedipine
  • Allergy to Cefixime
  • Warfarin
  • Lidocaine ( used as solvent for intravenous injections)
  • Stay away from vaccinations during the course of the treatment.

Special precautions

Pregnancy: Unless necessary, pregnant women must avoid Zifi 200 

Breast-feeding: This medicine can be conveyed through breast milk to the baby. Breast feeding mothers shoulddiscuss the risks and benefits of this drug with their healthcare professional

Side effects

There could be major and minor side effects of Zifi 200. The major ones need immediate attention. If the minor side effects continue to persist, it is advisable to consult with your healthcare provider.

Major side effects

  • Dizziness
  • Sore throat
  • Fever
  • Difficulty or painful urination
  • Severe Acidity
  • Black or tarry stools
  • Diarrhoea
  • Chest pain
  • Abdominal pain
  • Swelling of lips, hands, tongue, face, eyelids, feet  

Minor side effects

  • Flatulence, bloating and gastric issues
  • Alteration in taste

Further, when you take Zifi 200 it can alter the normal condition of the colon. This results in bacterial overgrowth in the intestine, which may trigger diarrhoea. 

What to do if you skip a dose

Take the skipped dose as soon as you remember provided it is not too close to the timing of the next scheduled dose.It is better to skip the dose in that case.


Overdose isserious and a medical emergency especially if accompanied with symptoms such as dizziness, chest pain, and abdominal pain.

Generic and brand name of Zifi 200

Generic: Cefixime

Brand name: Zifi 200mg 

Different manufacturing companies of Zifi 200

FDC Limited (Spectra) manufactures Zifi 200

Substitutes for the drug

Below is the list of medicines, which have the same composition, strength and form as Zifi 200 MG Tablet, and hence can be used as its substitute.

  • Mefix                                                              OysterLabs Limited
  • Cefix 200 MG Tablet                                    Cipla Ltd
  • Brutacef 200 MG Tablet                             MankindPharmaceuticals Ltd
  • Cefinar 200 MG Tablet                                ZydusCadila
  • Lyceft O 200 MG Tablet                              Hetero HealthcareLtd
  • Cefrax 200 MG Tablet                                 Cipla Ltd.
  • Fiximark 200 MG Tablet                             GlenmarkPharmaceuticals Ltd
  • Cefmost 200 MG Tablet                              TorrentPharmaceuticals Ltd.
  • Ocexim                                                             sho Pharma Pvt. Ltd
  • Scortax-200                                                   Scortis Labs (P)Ltd.
  • Mytxim O 200 MG Tablet                           MankindPharmaceuticals Ltd.
  • AIM-200                                                         Hinglaj Laboratories of India
  •  Xiotac DT                                                      Pharmatech Healthcare
  •  Cefi                                                               D S  Laboratories Pvt. Ltd.
  •  Claforan O 200 MG Tablet                        Sanofi India Ltd.
  •   Penixime                                                     Safe Pharmaceuticals
  •   Cemax                                                         Aan Pharma Pvt Ltd
  •   Saver Kid                                                      Alpic Remedies Ltd.
  •  Zeph                                                             Melody Healthcare Pvt. Ltd

  1. https://medlineplus.gov/druginfo/meds/a690007.html
  2. https://pubchem.ncbi.nlm.nih.gov/compound/azithromycin
  3. https://www.webmd.com/drugs/2/drug-3778-7011/cefixime-oral/cefixime-oral/details
  4. https://www.ncbi.nlm.nih.gov/pubmed/2663735




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